Defining features of the hair cell mechanoelectrical transducer channel (Q37350537)

19 August 2017

8 references

12 September 2019

11 October 2019

12 October 2019

28 November 2019

15 December 2019

10 August 2020

31 January 2021

25 January 2024

Defining features of the hair cell mechanoelectrical transducer channel (English)

1 reference

19 August 2017

1 reference

12 September 2019

sensory nervous system

1 reference

11 October 2019

1 reference

12 October 2019

1 reference

28 November 2019

1 reference

15 December 2019

2 references

10 August 2020

31 January 2021

1

Robert Fettiplace

1 reference

19 August 2017

28 May 2009

1 reference

PMC publication ID

2745616

19 August 2017

1 October 2009

8 references

12 September 2019

11 October 2019

12 October 2019

28 November 2019

15 December 2019

10 August 2020

31 January 2021

25 January 2024

9 references

19 August 2017

12 September 2019

11 October 2019

12 October 2019

28 November 2019

15 December 2019

10 August 2020

31 January 2021

25 January 2024

458

1 reference

19 August 2017

6

1 reference

19 August 2017

1115-1123

1 reference

Creative Commons Attribution-NonCommercial 4.0 International

19 August 2017

1 reference

Fast adaptation and Ca2 sensitivity of the mechanotransducer require myosin-XVa in inner but not outer cochlear hair cells

25 January 2024

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Localization of inner hair cell mechanotransducer channels using high-speed calcium imaging.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Cochlear amplification, outer hair cells and prestin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

TRPP2 and TRPV4 form a polymodal sensory channel complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

The varitint-waddler (Va) deafness mutation in TRPML3 generates constitutive, inward rectifying currents and causes cell degeneration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

TRP channels in mechanosensation: direct or indirect activation?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

TRP channels as candidates for hearing and balance abnormalities in vertebrates.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

The cells and logic for mammalian sour taste detection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Permeation and selectivity of TRP channels

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Ca2 changes the force sensitivity of the hair-cell transduction channel

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Probing the geometry of the inner vestibule of BK channels with sugars

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Lighting up the senses: FM1-43 loading of sensory cells through nonselective ion channels.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Polycystin-2 is an intracellular calcium release channel

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2 -permeable nonselective cation channel

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

High-resolution structure of hair-cell tip links

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Polycystin-L is a calcium-regulated cation channel permeable to calcium ions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Mechanisms of hair cell tuning

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Calcium imaging of single stereocilia in hair cells: localization of transduction channels at both ends of tip links

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Detection of Ca2 entry through mechanosensitive channels localizes the site of mechanoelectrical transduction in hair cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

The permeability of the endplate channel to organic cations in frog muscle

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Mechano-electrical transduction currents in isolated vestibular hair cells of the chick

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Voltage dependence of adaptation and active bundle movement in bullfrog saccular hair cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Ionic basis of the receptor potential in a vertebrate hair cell

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Regulation of the murine TRPP3 channel by voltage, pH, and changes in cell volume

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Linker-gating ring complex as passive spring and Ca(2 )-dependent machine for a voltage- and Ca(2 )-activated potassium channel

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Probing the pore of the auditory hair cell mechanotransducer channel in turtle

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Myosin and Adaptation by Hair Cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Mechanically and ATP-induced currents of mouse outer hair cells are independent and differentially blocked by d-tubocurarine

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Ca selectivity of the transduction channels in the hair cells of the frog sacculus

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Kinetics of the receptor current in bullfrog saccular hair cells.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog's saccular hair cell

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

The actions of calcium on the mechano-electrical transducer current of turtle hair cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Mechano-electrical transducer currents in hair cells of the cultured neonatal mouse cochlea

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

TRPML3 mutations cause impaired mechano-electrical transduction and depolarization by an inward-rectifier cation current in auditory hair cells of varitint-waddler mice

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Inhibition of TRPP3 channel by amiloride and analogs

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Permeation and inhibition of polycystin-L channel by monovalent organic cations

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

The transduction channel filter in auditory hair cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

The aminoglycoside antibiotic dihydrostreptomycin rapidly enters mouse outer hair cells through the mechano-electrical transducer channels

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

The remarkable mechanical strength of polycystin-1 supports a direct role in mechanotransduction

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Polycystin-2 accelerates Ca2 release from intracellular stores in Caenorhabditis elegans

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

A polycystin-2-like large conductance cation channel in rat left ventricular myocytes

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Differences in mechano-transducer channel kinetics underlie tonotopic distribution of fast adaptation in auditory hair cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

A quantitative comparison of mechanoelectrical transduction in vestibular and auditory hair cells of neonatal mice.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

The permeability of the cGMP‐activated channel to organic cations in retinal rods of the tiger salamander

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Block by amiloride and its derivatives of mechano-electrical transduction in outer hair cells of mouse cochlear cultures

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Activation and adaptation of transducer currents in turtle hair cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Amiloride blocks the mechano-electrical transduction channel of hair cells of the chick.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2745616

Two components of transducer adaptation in auditory hair cells

2 September 2018

1 reference

12 December 2020

Blockage of the transduction channels of hair cells in the bullfrog's sacculus by aminoglycoside antibiotics

1 reference

12 December 2020

Insights into the pore of the hair cell transducer channel from experiments with permeant blockers

1 reference

12 December 2020

Gadolinium blocks mechano-electric transducer current in chick cochlear hair cells

1 reference

12 December 2020

Mechanoelectrical transduction of adult outer hair cells studied in a gerbil hemicochlea

1 reference

12 December 2020

Calcium permeation of the turtle hair cell mechanotransducer channel and its relation to the composition of endolymph

1 reference

12 December 2020

Gating of the polycystin ion channel signaling complex in neurons and kidney cells

1 reference

12 December 2020

Tonotopic variation in the conductance of the hair cell mechanotransducer channel

1 reference

12 December 2020

Submembraneous microtubule cytoskeleton: interaction of TRPP2 with the cell cytoskeleton

1 reference

12 December 2020

Intracellular calcium suppresses mechano-electrical transduction current in chick cochlear hair cells

1 reference

12 December 2020

A large-conductance calcium-selective mechanotransducer channel in mammalian cochlear hair cells

1 reference

12 December 2020

The dimensions and structural attachments of tip links in mammalian cochlear hair cells and the effects of exposure to different levels of extracellular calcium

1 reference

12 December 2020

10.1007/S00424-009-0683-X

Identifiers

DOI

1 reference

19 August 2017

1 reference

PMC publication ID

2745616

19 August 2017

PubMed publication ID

19475417

1 reference

PMC publication ID

2745616