Preventing tumor escape by targeting a post-proteasomal trimming independent epitope. (Q37346707)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27697836 AND SRC:MED&resulttype=core&format=json

24 March 2020

title

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope (English)

1 reference

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24 March 2020

2

1 reference

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24 March 2020

Peter-Michael Kloetzel

3

1 reference

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24 March 2020

Bianca Weißbrich

4

1 reference

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24 March 2020

Cynthia Perez

5

1 reference

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24 March 2020

Ton Schumacher

10

1 reference

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24 March 2020

Dirk H Busch

12

1 reference

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24 March 2020

8

John Sidney

1 reference

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24 March 2020

9

Alessandro Sette

1 reference

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24 March 2020

11

Christin Keller

1 reference

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24 March 2020

1

Ana Textor

1 reference

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24 March 2020

6

Jehad Charo

1 reference

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24 March 2020

7

Kathleen Anders

1 reference

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24 March 2020

13

Ulrike Seifert

1 reference

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24 March 2020

14

Thomas Blankenstein

1 reference

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24 March 2020

language of work or name

English

0 references

publication date

3 October 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27697836 AND SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

24 March 2020

published in

1 reference

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24 March 2020

volume

213

1 reference

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24 March 2020

issue

11

1 reference

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24 March 2020

page(s)

2333-2348

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Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation

24 March 2020

cites work

1 reference

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Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer.

6 September 2017

1 reference

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TCR-ligand koff rate correlates with the protective capacity of antigen-specific CD8 T cells for adoptive transfer

6 September 2017

1 reference

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Induction of protective antitumor immunity through attenuation of ERAAP function

6 September 2017

1 reference

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Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity

6 September 2017

1 reference

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Fas expression by tumor stroma is required for cancer eradication

6 September 2017

1 reference

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Molecular pathways: comparing the effects of drugs and T cells to effectively target oncogenes

6 September 2017

1 reference

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Peptidases trimming MHC class I ligands

6 September 2017

1 reference

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The role of classical and non-classical HLA class I antigens in human tumors

6 September 2017

1 reference

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MHC class I molecules act as tumor suppressor genes regulating the cell cycle gene expression, invasion and intrinsic tumorigenicity of melanoma cells.

6 September 2017

1 reference

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Oncogene-Targeting T Cells Reject Large Tumors while Oncogene Inactivation Selects Escape Variants in Mouse Models of Cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Human cytomegalovirus microRNA miR-US4-1 inhibits CD8( ) T cell responses by targeting the aminopeptidase ERAP1

6 September 2017

1 reference

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Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Association of IFN-gamma signal transduction defects with impaired HLA class I antigen processing in melanoma cell lines

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Quantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Immune selective pressure and HLA class I antigen defects in malignant lesions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

The role of stroma in immune recognition and destruction of well-established solid tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Proteasome and peptidase function in MHC-class-I-mediated antigen presentation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Adoptive T cell therapy using antigen-specific CD8 T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

CD4( ) T cells eliminate MHC class II-negative cancer cells in vivo by indirect effects of IFN-gamma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Natural variation of the expression of HLA and endogenous antigen modulates CTL recognition in an in vitro melanoma model

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

The Sequence Alteration Associated with a Mutational Hotspot in p53 Protects Cells From Lysis by Cytotoxic T Lymphocytes Specific for a Flanking Peptide Epitope

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice

6 September 2017

1 reference

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Protective Immunity Does Not Correlate with the Hierarchy of Virus-specific Cytotoxic T Cell Responses to Naturally Processed Peptides

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Targeting p53 as a general tumor antigen

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Loss of functional beta 2-microglobulin in metastatic melanomas from five patients receiving immunotherapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Interaction of MHC class I molecules with the transporter associated with antigen processing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

In vivo imaging of an inducible oncogenic tumor antigen visualizes tumor progression and predicts CTL tolerance

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Measurement of MHC/peptide interactions by gel filtration

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Cellular senescence bypass screen identifies new putative tumor suppressor genes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Phase I study of adoptive T-cell therapy using antigen-specific CD8 T cells for the treatment of patients with metastatic melanoma.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

IFN unresponsiveness in LNCaP cells due to the lack of JAK1 gene expression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Unresponsiveness to interferon associated with STAT1 protein deficiency in a gastric adenocarcinoma cell line.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Blockade of TGF-β signaling greatly enhances the efficacy of TCR gene therapy of cancer

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Depot formation of doxycycline impairs Tet-regulated gene expression in vivo.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Visualizing the dynamic of adoptively transferred T cells during the rejection of large established tumors.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Anti-CD40 conditioning enhances the T(CD8) response to a highly tolerogenic epitope and subsequent immunotherapy of simian virus 40 T antigen-induced pancreatic tumors

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

CpG motifs as proinflammatory factors render autochthonous tumors permissive for infiltration and destruction

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Bystander elimination of antigen loss variants in established tumors

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

In vivo ligation of CD40 enhances priming against the endogenous tumor antigen and promotes CD8 T cell effector function in SV40 T antigen transgenic mice

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Complete loss of HLA class I antigen expression on melanoma cells: a result of successive mutational events.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

CD4 T cell--mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoietic cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

Two complementary methods for predicting peptides binding major histocompatibility complex molecules

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5068242

The Fate of Low Affinity Tumor-Specific CD8 T Cells in Tumor-Bearing Mice

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27697836

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Quantitation of CD8( ) T-lymphocyte responses to multiple epitopes from simian virus 40 (SV40) large T antigen in C57BL/6 mice immunized with SV40, SV40 T-antigen-transformed cells, or vaccinia virus recombinants expressing full-length T antigen or

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27697836

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

HLA class I expression and chromosomal deletions at 6p and 15q in head and neck squamous cell carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27697836

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20160636

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27697836 AND SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27697836 AND SRC:MED&resulttype=core&format=json

24 March 2020

PubMed publication ID

27697836

1 reference