Understanding the effect of API properties on bioavailability through absorption modeling (Q37323446)

19 August 2017

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title

Understanding the effect of API properties on bioavailability through absorption modeling (English)

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19 August 2017

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Filippos Kesisoglou

1

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19 August 2017

Yunhui Wu

series ordinal

2

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19 August 2017

language of work or name

English

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publication date

6 November 2008

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19 August 2017

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19 August 2017

10

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19 August 2017

4

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19 August 2017

516-525

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Salt formation to improve drug solubility

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A strategy for preclinical formulation development using GastroPlus as pharmacokinetic simulation tool and a statistical screening design applied to a dog study

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Classification of orally administered drugs on the World Health Organization Model list of Essential Medicines according to the biopharmaceutics classification system

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Predicting the impact of physiological and biochemical processes on oral drug bioavailability

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1 reference

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6 September 2017

1 reference

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Improving drug solubility for oral delivery using solid dispersions

6 September 2017

1 reference

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Application of gastrointestinal simulation for extensions for biowaivers of highly permeable compounds

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1 reference

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An integrated model for determining causes of poor oral drug absorption.

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1 reference

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Guidance in the setting of drug particle size specifications to minimize variability in absorption

26 June 2018

1 reference

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Theoretical dissolution model of poly-disperse drug particles in biorelevant media

26 June 2018

1 reference

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Molecular properties of WHO essential drugs and provisional biopharmaceutical classification

2 September 2018

1 reference

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The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: a Beagle dog model predicts improved bioavailability and diminished food effect on absorption in human

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General solution for diffusion-controlled dissolution of spherical particles. 1. Theory.

2 September 2018

1 reference

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Dissolution modeling: factors affecting the dissolution rates of polydisperse powders.

2 September 2018

1 reference

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Absorption potential: estimating the fraction absorbed for orally administered compounds

2 September 2018

1 reference

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A provisional biopharmaceutical classification of the top 200 oral drug products in the United States, Great Britain, Spain, and Japan

2 September 2018

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12 December 2020

Physicochemical properties of the nucleoside prodrug R1626 leading to high oral bioavailability

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12 December 2020

Development of clinical dosage forms for a poorly water soluble drug I: Application of polyethylene glycol-polysorbate 80 solid dispersion carrier system

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12 December 2020

Mixing-tank model for predicting dissolution rate control or oral absorption

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12 December 2020

10.1208/S12248-008-9061-4

Identifiers

DOI

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Dimensions Publication ID

19 August 2017

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19 August 2017

PubMed publication ID

19002590

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