Deleting the accessory subunit KChIP2 results in loss of I(to,f) and increased I(K,slow) that maintains normal action potential configuration. (Q37317751)

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English	Deleting the accessory subunit KChIP2 results in loss of I(to,f) and increased I(K,slow) that maintains normal action potential configuration.	scientific article

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22 January 2020

Deleting the accessory subunit KChIP2 results in loss of I(to,f) and increased I(K,slow) that maintains normal action potential configuration (English)

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22 January 2020

Morten B Thomsen

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22 January 2020

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Eugene A Sosunov

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22 January 2020

Evgeny P Anyukhovsky

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22 January 2020

Nazira Ozgen

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22 January 2020

Penelope A Boyden

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22 January 2020

Michael R Rosen

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22 January 2020

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27 November 2008

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22 January 2020

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22 January 2020

6

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22 January 2020

3

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22 January 2020

370-377

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22 January 2020

Post-transcriptional gene silencing of KChIP2 and Navbeta1 in neonatal rat cardiac myocytes reveals a functional association between Na and Ito currents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

PPARalpha-mediated remodeling of repolarizing voltage-gated K (Kv) channels in a mouse model of metabolic cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Distinct cellular and molecular mechanisms underlie functional remodeling of repolarizing K currents with left ventricular hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Kv4.3 is not required for the generation of functional Ito,f channels in adult mouse ventricles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Structural basis for modulation of Kv4 K channels by auxiliary KChIP subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Functional modulation of the transient outward current Ito by KCNE beta-subunits and regional distribution in human non-failing and failing hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Assessing the proarrhythmic potential of drugs: current status of models and surrogate parameters of torsades de pointes arrhythmias.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Molecular physiology of cardiac repolarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

The cAMP response element binding protein modulates expression of the transient outward current: implications for cardiac memory.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Drug-induced prolongation of the QT interval

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Regulation of Kv4.3 current by KChIP2 splice variants: a component of native cardiac I(to)?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Regulation of KChIP2 potassium channel beta subunit gene expression underlies the gradient of transient outward current in canine and human ventricle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Modulation of A-type potassium channels by a family of calcium sensors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Electrophysiological remodeling in hypertrophy and heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Four kinetically distinct depolarization-activated K currents in adult mouse ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Molecular basis of transient outward potassium current downregulation in human heart failure: a decrease in Kv4.3 mRNA correlates with a reduction in current density

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Heteropodatoxins: peptides isolated from spider venom that block Kv4.2 potassium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

The spectrum of symptoms and QT intervals in carriers of the gene for the long-QT syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

9 September 2017

Targeted replacement of KV1.5 in the mouse leads to loss of the 4-aminopyridine-sensitive component of I(K,slow) and resistance to drug-induced qt prolongation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

28 September 2017

Attenuation of the slow component of delayed rectification, action potential prolongation, and triggered activity in mice expressing a dominant-negative Kv2 alpha subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

28 September 2017

Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

28 September 2017

Sotalol testing unmasks altered repolarization in patients with suspected acquired long-QT-syndrome--a case-control pilot study using i.v. sotalol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

26 June 2018

Electrotonic modulation of the T wave and cardiac memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

26 June 2018

Contribution of N- and C-terminal Kv4.2 channel domains to KChIP interaction [corrected].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

2 September 2018

Heterogeneous expression of repolarizing, voltage-gated K currents in adult mouse ventricles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

2 September 2018

Interactions between antiarrhythmic drugs and cardiac memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

2 September 2018

Molecular basis of transient outward K current diversity in mouse ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

2 September 2018

Transient outward current, Ito1, is altered in cardiac memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731656

2 September 2018

Spatial alterations of Kv channels expression and K( ) currents in post-MI remodeled rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/19251214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal electrical properties of myocytes from chronically infarcted canine heart. Alterations in Vmax and the transient outward current

1 reference

https://pubmed.ncbi.nlm.nih.gov/19251214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations of K currents in isolated human ventricular myocytes from patients with terminal heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/19251214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of transient outward current in human ventricular myocytes from patients with terminal heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/19251214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapidly activating sustained K current modulates repolarization and excitation–contraction coupling in adult mouse ventricle

1 reference

https://pubmed.ncbi.nlm.nih.gov/19251214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taking the “Idio” out of “Idiosyncratic”: Predicting Torsades de Pointes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19251214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KChIP2 modulates the cell surface expression of Kv 1.5-encoded K( ) channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/19251214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19251214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted expression of a dominant-negative K(v)4.2 K( ) channel subunit in the mouse heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/19251214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.HRTHM.2008.11.023

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22 January 2020

PMC publication ID

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22 January 2020

PubMed publication ID

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22 January 2020

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