Bioactivation and Regioselectivity of Pig Cytochrome P450 3A29 towards Aflatoxin B₁. (Q37285690)

19 August 2017

Bioactivation and Regioselectivity of Pig Cytochrome P450 3A29 towards Aflatoxin B₁. (English)

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19 August 2017

10

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31 May 2020

Yiqun Deng

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31 May 2020

author name string

Jun Wu

1

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31 May 2020

Ruohong Chen

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31 May 2020

Caihui Zhang

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Kangbai Li

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31 May 2020

Weiying Xu

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Lijuan Wang

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Qingmei Chen

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Peiqiang Mu

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Jun Jiang

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publication date

12 September 2016

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19 August 2017

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volume

8

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issue

9

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Creative Commons Attribution 4.0 International

31 May 2020

copyright license

start time

12 September 2016

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April 2022 Public Data File from Crossref

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copyrighted

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Influence of P450 3A4 SRS-2 residues on cooperativity and/or regioselectivity of aflatoxin B(1) oxidation.

6 September 2017

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Determinants of specificity for aflatoxin B1-8,9-epoxide in alpha-class glutathione S-transferases

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Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductase

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Reaction of aflatoxin B1 exo-8,9-epoxide with DNA: kinetic analysis of covalent binding and DNA-induced hydrolysis

6 September 2017

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A novel aldehyde reductase with activity towards a metabolite of aflatoxin B1 is expressed in rat liver during carcinogenesis and following the administration of an anti-oxidant

6 September 2017

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6 September 2017

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Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1

6 September 2017

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6 September 2017

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6 September 2017

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Comparison of the substrate kinetics of pig CYP3A29 with pig liver microsomes and human CYP3A4.

6 September 2017

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14 September 2017

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A review of the dose-response induction of DNA adducts by aflatoxin B1 and its implications to quantitative cancer-risk assessment

14 September 2017

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14 September 2017

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Structure-function analysis of porcine cytochrome P450 3A29 in the hydroxylation of T-2 toxin as revealed by docking and mutagenesis studies

26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4.

26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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3 September 2018

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3 September 2018

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3 September 2018

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Aflatoxin B1 activation in human lung.

3 September 2018

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Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.

3 September 2018

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Characterization of drug metabolizing activities in pig hepatocytes for use in bioartificial liver devices: comparison with other hepatic cellular models

3 September 2018

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Expression of Cytochrome-P450-3A5 in Escherichia Coli: Effects of 5′ Modification, Purification, Spectral Characterization, Reconstitution Conditions, and Catalytic Activities

21 January 2018

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Alanine-scanning mutagenesis of a putative substrate recognition site in human cytochrome P450 3A4. Role of residues 210 and 211 in flavonoid activation and substrate specificity

21 January 2018

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12 December 2020

Establishment of functional human cytochrome P450 monooxygenase systems in Escherichia coli

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12 December 2020

Trp266 determines the binding specificity of a porcine aflatoxin B₁ aldehyde reductase for aflatoxin B₁-dialdehyde

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12 December 2020

Selective impairment of drug-metabolizing enzymes in pig liver during subchronic dietary exposure to aflatoxin B1

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12 December 2020

Biochemical basis for the extreme sensitivity of turkeys to aflatoxin B(1)

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12 December 2020

Use of the steroid derivative RPR 106541 in combination with site-directed mutagenesis for enhanced cytochrome P-450 3A4 structure/function analysis

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12 December 2020

Effects of AFB1 on CYP 1A1, 1A2 and 3A6 mRNA, and P450 expression in primary culture of rabbit hepatocytes

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Identifiers

DOI

10.3390/TOXINS8090267

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27626447 AND SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27626447 AND SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

27626447

1 reference