Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs. (Q37282551)

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scientific article published on 09 December 2015

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English	Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs.	scientific article published on 09 December 2015

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scholarly article

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2 March 2020

Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs (English)

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2 March 2020

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based on heuristic

inferred from title

single-cell cloning

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based on heuristic

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monoclonal antibody

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1

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2 March 2020

Paola Migliorini

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2 March 2020

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Michele Bombardieri

2

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2 March 2020

Emanuela Carlotti

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2 March 2020

Federico Pratesi

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2 March 2020

William Robinson

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2 March 2020

Costantino Pitzalis

7

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2 March 2020

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9 December 2015

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2 March 2020

Annals of the Rheumatic Diseases

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2 March 2020

75

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2 March 2020

10

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2 March 2020

1866-1875

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2 March 2020

Association between anti-Porphyromonas gingivalis or anti-α-enolase antibody and severity of periodontitis or rheumatoid arthritis (RA) disease activity in RA.

1 reference

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6 September 2017

Associations of antibodies against citrullinated peptides with human leukocyte antigen-shared epitope and smoking prior to the development of rheumatoid arthritis

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Adaptive immunity in rheumatoid arthritis: anticitrulline and other antibodies in the pathogenesis of rheumatoid arthritis

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Macrophage clearance of neutrophil extracellular traps is a silent process

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Antibodies from patients with rheumatoid arthritis target citrullinated histone 4 contained in neutrophils extracellular traps

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6 September 2017

NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis

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6 September 2017

New learnings on the pathophysiology of RA from synovial biopsies.

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Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

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Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis

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6 September 2017

V‐region gene analysis of locally defined synovial B and plasma cells reveals selected B cell expansion and accumulation of plasma cell clones in rheumatoid arthritis

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6 September 2017

Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis

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Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: from inflammation to autoimmunity and tissue damage/remodeling.

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6 September 2017

Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans

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6 September 2017

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation.

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6 September 2017

Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium

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6 September 2017

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

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B-cell self-tolerance in humans

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6 September 2017

Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis

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Identification of citrullinated alpha-enolase as a candidate autoantigen in rheumatoid arthritis

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B cells in rheumatoid synovitis

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Predominant autoantibody production by early human B cell precursors

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The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the alpha- and beta-chains of fibrin

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6 September 2017

Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies

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Single-step separation of red blood cells. Granulocytes and mononuclear leukocytes on discontinuous density gradients of Ficoll-Hypaque

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In the rheumatoid pannus, anti-filaggrin autoantibodies are produced by local plasma cells and constitute a higher proportion of IgG than in synovial fluid and serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/26659717

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphoid neogenesis in rheumatoid synovitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26659717

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1136/ANNRHEUMDIS-2015-208356

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659717 AND SRC:MED&resulttype=core&format=json

2 March 2020

release_33ofpljdwzgolknnxhmlujdrdm

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https://api.fatcat.wiki/v0/release/33ofpljdwzgolknnxhmlujdrdm

24 November 2022

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2 March 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26659717 AND SRC:MED&resulttype=core&format=json

2 March 2020

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