Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes? (Q37271799)

19 August 2017

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title

Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes? (English)

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single-nucleotide polymorphism

19 August 2017

main subject

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Virendra Singh

1

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19 August 2017

Devendra Parmar

series ordinal

2

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19 August 2017

Mahendra Pratap Singh

series ordinal

3

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19 August 2017

publication date

1 October 2008

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19 August 2017

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19 August 2017

volume

26

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19 August 2017

issue

8

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19 August 2017

page(s)

769-783

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Cigarette smoking, cytochrome P4501A1 polymorphisms, and breast cancer among African-American and white women

19 August 2017

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Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer

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Germline mutational analysis of CDH1 and pathologic features in familial cancer syndrome with diffuse gastric cancer/breast cancer proband in a Chinese family

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Ten genes for inherited breast cancer.

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Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells

21 January 2018

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Pairwise combinations of estrogen metabolism genotypes in postmenopausal breast cancer etiology

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A novel CYP1A1 gene polymorphism in African-Americans.

21 January 2018

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Allelic variants of human cytochrome P450 1A1 (CYP1A1): effect of T461N and I462V substitutions on steroid hydroxylase specificity

21 January 2018

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Genetic susceptibility to breast cancer in French-Canadians: role of carcinogen-metabolizing enzymes and gene-environment interactions

21 January 2018

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Polymorphisms in CYP1A1 and smoking: no association with breast cancer risk

21 January 2018

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Cytochrome P450 1A2 (CYP1A2) activity, mammographic density, and oxidative stress: a cross-sectional study

21 January 2018

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Population-based case-control study of AhR (aryl hydrocarbon receptor) and CYP1A2 polymorphisms and breast cancer risk

21 January 2018

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Breast density and polymorphisms in genes coding for CYP1A2 and COMT: the Multiethnic Cohort

21 January 2018

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Functional characterization of cytochrome P450 2B6 allelic variants

21 January 2018

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21 January 2018

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The association of CYP2D6 *10 polymorphism with breast cancer risk and clinico-pathologic characteristics in Chinese women.

21 January 2018

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Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes

21 January 2018

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16Alpha-hydroxylation of estrone by human cytochrome P4503A4/5.

21 January 2018

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CYP gene polymorphisms and early menarche

21 January 2018

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Significance of the minor cytochrome P450 3A isoforms.

21 January 2018

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Polymorphisms in cytochrome P4503A5 (CYP3A5) may be associated with race and tumor characteristics, but not metabolism and side effects of tamoxifen in breast cancer patients

21 January 2018

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Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene

21 January 2018

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Discovery of a functional polymorphism in human glutathione transferase zeta by expressed sequence tag database analysis

21 January 2018

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Zeta, a novel class of glutathione transferases in a range of species from plants to humans

21 January 2018

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Polymorphism of glutathione S-transferase omega gene and risk of cancer

21 January 2018

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Glutathione S-transferase M1 and T1 genetic polymorphisms, alcohol consumption and breast cancer risk

21 January 2018

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https://api.crossref.org/works/10.1080/07357900801953196

Marine n-3 fatty acid intake, glutathione S-transferase polymorphisms and breast cancer risk in post-menopausal Chinese women in Singapore

21 January 2018

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https://api.crossref.org/works/10.1080/07357900801953196

Genetic polymorphism at the glutathione S-transferase (GST) P1 locus is a breast cancer risk modifier

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Genetic polymorphisms in human SULT1A1 and UGT1A1 genes associate with breast tumor characteristics: a case-series study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Modifying effects of sulfotransferase 1A1 gene polymorphism on the association of breast cancer risk with body mass index or endogenous steroid hormones

21 January 2018

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https://api.crossref.org/works/10.1080/07357900801953196

SULT1A1 genotype, active and passive smoking, and breast cancer risk by age 50 years in a German case-control study

21 January 2018

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https://api.crossref.org/works/10.1080/07357900801953196

Genotypic and allelic frequencies of SULT1A1 polymorphisms in women receiving adjuvant tamoxifen therapy

21 January 2018

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https://api.crossref.org/works/10.1080/07357900801953196

Cancer and molecular biomarkers of phase 2.

21 January 2018

1 reference

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UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients

21 January 2018

1 reference

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Meta-analyses of observational and genetic association studies of folate intakes or levels and breast cancer risk

21 January 2018

1 reference

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One-carbon metabolism and breast cancer risk: no association of MTHFR, MTR, and TYMS polymorphisms in the GENICA study from Germany

21 January 2018

1 reference

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The Common 677C>T Gene Polymorphism of Methylenetetrahydrofolate Reductase Gene is not Associated with Breast Cancer Risk

21 January 2018

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https://api.crossref.org/works/10.1080/07357900801953196

Polymorphisms in the MTHFR gene are associated with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Breast cancer risk and methylenetetrahydrofolate reductase polymorphism

21 January 2018

1 reference

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Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin

21 January 2018

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Oxidative metabolism of tamoxifen to Z-4-hydroxy-tamoxifen by cytochrome P450 isoforms: an appraisal of in vitro studies

21 January 2018

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Baculovirus vectors: novel mammalian cell gene-delivery vehicles and their applications

21 January 2018

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Implications of cytochrome P450 genetic polymorphisms on the toxicity of antitumor agents

21 January 2018

1 reference

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The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Genetic polymorphism of CYP2C9 and CYP2C19 in a Bolivian population: an investigative and comparative study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

CYP2C8 polymorphism among the Portuguese

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

A novel intronic mutation that may affect genotyping result of CYP2C8 by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is strongly associated with CYP2C8*3 in a South American population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Linkage between the CYP2C8 and CYP2C9 genetic polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Metabolism of tamoxifen by recombinant human cytochrome P450 enzymes: formation of the 4-hydroxy, 4'-hydroxy and N-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Identification of human CYP forms involved in the activation of tamoxifen and irreversible binding to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Genotype of metabolic enzymes and the benefit of tamoxifen in postmenopausal breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Influence of garlic (Allium sativum) on the pharmacokinetics of docetaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Combination vinorelbine and capecitabine for metastatic breast cancer using a non-body surface area dosing scheme

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Impact of the haplotype CYP3A4*16B harboring the Thr185Ser substitution on paclitaxel metabolism in Japanese patients with cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Glutathione S-transferase M1 null genotype: lack of association with tumour characteristics and survival in advanced breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Genetic polymorphisms in glutathione-S-transferase genes (GSTM1, GSTT1, GSTP1) and survival after chemotherapy for invasive breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Combined COMT and GST genotypes and hormone replacement therapy associated breast cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Association between a glutathione S-transferase A1 promoter polymorphism and survival after breast cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Genetic polymorphisms of SULT1A1 and SULT1E1 and the risk and survival of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Quaternary ammonium-linked glucuronidation of trans-4-hydroxytamoxifen, an active metabolite of tamoxifen, by human liver microsomes and UDP-glucuronosyltransferase 1A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Methylenetetrahydrofolate reductase polymorphism, diet, and breast cancer in Korean women

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

MTHFR polymorphisms, dietary folate intake, and breast cancer risk: results from the Shanghai Breast Cancer Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Reduced breast cancer risk with increasing serum folate in a case-control study of the C677T genotype of the methylenetetrahydrofolate reductase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

MTHFR genotypes and breast cancer survival after surgery and chemotherapy: a report from the Shanghai Breast Cancer Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6.

21 January 2018

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https://api.crossref.org/works/10.1080/07357900801953196

Bench to bedside: Pharmacogenomics, adverse drug interactions, and the cytochrome P450 system

21 January 2018

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https://api.crossref.org/works/10.1080/07357900801953196

Increased transcriptional activity of the CYP3A4*1B promoter variant

21 January 2018

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https://api.crossref.org/works/10.1080/07357900801953196

Human phenol sulfotransferases SULT1A2 and SULT1A1: genetic polymorphisms, allozyme properties, and human liver genotype-phenotype correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Six novel UDP-glucuronosyltransferase (UGT1A3) polymorphisms with varying activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Methylenetetrahydrofolate reductase (MTHFR) and breast cancer risk: a nested-case-control study and a pooled meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Polymorphism in the CYP2D6 Tamoxifen-Metabolizing Gene Influences Clinical Effect but Not Hot Flashes: Data From the Italian Tamoxifen Trial

21 January 2018

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Population-based study of risk of breast cancer in carriers of BRCA2 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

The CYP3A4*1B polymorphism has no functional significance and is not associated with risk of breast or ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Association of SULT1A1 and UGT1A1 polymorphisms with breast cancer risk and phenotypes in Russian women

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Sulfotransferase 1A1 genotype as a potential modifier of breast cancer risk among premenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Role of Estradiol Metabolism and CYP1A1 Polymorphisms in Breast Cancer Risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

Comparisons of CYP1A2 genetic polymorphisms, enzyme activity and the genotype-phenotype relationship in Swedes and Koreans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/07357900801953196

10.1080/07357900801953196

21 January 2018

Identifiers

DOI

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19 August 2017

1 reference