DNA topoisomerases: harnessing and constraining energy to govern chromosome topology (Q37255381)

19 August 2017

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title

DNA topoisomerases: harnessing and constraining energy to govern chromosome topology (English)

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19 August 2017

Allyn J Schoeffler

1

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19 August 2017

James M Berger

series ordinal

2

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19 August 2017

publication date

1 February 2008

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Quarterly Reviews of Biophysics

19 August 2017

published in

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19 August 2017

volume

41

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19 August 2017

issue

1

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19 August 2017

page(s)

41-101

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The open state of human topoisomerase I as probed by molecular dynamics simulation

19 August 2017

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Energy coupling in type II topoisomerases: why do they hydrolyze ATP?

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Electrostatics of nanosystems: application to microtubules and the ribosome

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21 January 2018

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Toprim--a conserved catalytic domain in type IA and II topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins

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The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs.

21 January 2018

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The role of topoisomerase IV in partitioning bacterial replicons and the structure of catenated intermediates in DNA replication

21 January 2018

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Functional interactions of DNA topoisomerases with a human replication origin

21 January 2018

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21 January 2018

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Solution structure of the C4 zinc finger domain of HDM2.

21 January 2018

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DNA topoisomerase IIbeta and neural development

21 January 2018

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A DNA‐Topoisomerase‐11–Binding Protein with Eight Repeating Regions Similar to DNA‐repair Enzymes and to a Cell‐Cycle Regulator

21 January 2018

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The Bloom's syndrome gene product interacts with topoisomerase III

21 January 2018

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BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

21 January 2018

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21 January 2018

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21 January 2018

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Probing the two-gate mechanism of DNA gyrase using cysteine cross-linking.

21 January 2018

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Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

21 January 2018

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Mutagenesis of E477 or K505 in the B' domain of human topoisomerase II beta increases the requirement for magnesium ions during strand passage

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Unlocking and opening a DNA gate

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21 January 2018

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Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine

21 January 2018

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21 January 2018

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A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase

21 January 2018

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Mechanism of topology simplification by type II DNA topoisomerases

21 January 2018

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Conformational and thermodynamic properties of supercoiled DNA.

21 January 2018

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21 January 2018

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21 January 2018

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Topoisomerase IV, not gyrase, decatenates products of site-specific recombination inEscherichia coli

21 January 2018

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Mechanism of plasmid-mediated quinolone resistance

21 January 2018

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Probing the role of the ATP-operated clamp in the strand-passage reaction of DNA gyrase

21 January 2018

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21 January 2018

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Remote phosphate contacts trigger assembly of the active site of DNA topoisomerase IB.

21 January 2018

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Characterization of the interaction between topoisomerase II and DNA by transcriptional footprinting

21 January 2018

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An ATP-dependent supercoiling topoisomerase of Chlamydomonas reinhardtii affects accumulation of specific chloroplast transcripts

21 January 2018

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Topoisomerase V relaxes supercoiled DNA by a constrained swiveling mechanism

21 January 2018

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Structure of the N-terminal fragment of topoisomerase V reveals a new family of topoisomerases

21 January 2018

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DNA gyrase subunit stoichiometry and the covalent attachment of subunit A to DNA during DNA cleavage

21 January 2018

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RHL1 is an essential component of the plant DNA topoisomerase VI complex and is required for ploidy-dependent cell growth

21 January 2018

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Structure of the recA protein–ADP complex

21 January 2018

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Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases

21 January 2018

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A Model for the Mechanism of Human Topoisomerase I

21 January 2018

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A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay

21 January 2018

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Reconstitution of human topoisomerase I by fragment complementation

21 January 2018

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The domain organization of human topoisomerase I

21 January 2018

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T4 DNA-delay proteins, required for specific DNA replication, form a complex that has ATP-dependent DNA topoisomerase activity

21 January 2018

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Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog

21 January 2018

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A strand-passage conformation of DNA gyrase is required to allow the bacterial toxin, CcdB, to access its binding site

21 January 2018

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Single-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase II

21 January 2018

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DNA topoisomerase V is a relative of eukaryotic topoisomerase I from a hyperthermophilic prokaryote

21 January 2018

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Structure and mechanism of helicases and nucleic acid translocases

21 January 2018

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Glutamate racemase from Mycobacterium tuberculosis inhibits DNA gyrase by affecting its DNA-binding

21 January 2018

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Structure and conformational changes of DNA topoisomerase II visualized by electron microscopy

21 January 2018

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21 January 2018

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Simplification of DNA Topology Below Equilibrium Values by Type II Topoisomerases

21 January 2018

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A superhelical spiral in the Escherichia coli DNA gyrase A C-terminal domain imparts unidirectional supercoiling bias.

21 January 2018

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Crystal structure of reverse gyrase: insights into the positive supercoiling of DNA

21 January 2018

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Investigating the role of the latch in the positive supercoiling mechanism of reverse gyrase

21 January 2018

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Studies of a positive supercoiling machine. Nucleotide hydrolysis and a multifunctional "latch" in the mechanism of reverse gyrase

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The probabilities of supercoil removal and decatenation by yeast DNA topoisomerase II.

21 January 2018

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Multiple modes of Escherichia coli DNA gyrase activity revealed by force and torque

21 January 2018

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Thirty years of Escherichia coli DNA gyrase: from in vivo function to single-molecule mechanism.

21 January 2018

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Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp

21 January 2018

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The role of GyrB in the DNA cleavage-religation reaction of DNA gyrase: a proposed two metal-ion mechanism

21 January 2018

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Structure and function of an archaeal topoisomerase VI subunit with homology to the meiotic recombination factor Spo11

21 January 2018

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Reverse gyrase: an insight into the role of DNA-topoisomerases

21 January 2018

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DNA topoisomerase II selects DNA cleavage sites based on reactivity rather than binding affinity.

21 January 2018

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Interdomain communication in DNA topoisomerase II. DNA binding and enzyme activation.

21 January 2018

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Site-specific cleavage of DNA by E. coli DNA gyrase

21 January 2018

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DNA transport by a type II topoisomerase: direct evidence for a two-gate mechanism

21 January 2018

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Crystal structure of an IHF-DNA complex: a protein-induced DNA U-turn

21 January 2018

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The C-terminal domain of the Escherichia coli DNA gyrase A subunit is a DNA-binding protein

21 January 2018

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Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA

21 January 2018

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Crystal structure of the breakage-reunion domain of DNA gyrase

21 January 2018

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Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous crystal structures

21 January 2018

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The structure of Escherichia coli DNA topoisomerase III

21 January 2018

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Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA

21 January 2018

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DNA gyrase action involves the introduction of transient double-strand breaks into DNA

21 January 2018

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Bipartite nuclear localization signals in the C terminus of human topoisomerase II alpha.

21 January 2018

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Control of cell division by sex factor F in Escherichia coli. I. The 42.84-43.6 F segment couples cell division of the host bacteria with replication of plasmid DNA.

21 January 2018

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Control of cell division by sex factor F in Escherichia coli. II. Identification of genes for inhibitor protein and trigger protein on the 42.84-43.6 F segment

21 January 2018

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Structure of catabolite gene activator protein at 2.9 A resolution suggests binding to left-handed B-DNA.

21 January 2018

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Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: implications for enzyme action ahead of replication forks

21 January 2018

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The 1.2-megabase genome sequence of Mimivirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Action of nicking-closing enzyme on supercoiled and nonsupercoiled closed circular DNA: formation of a Boltzmann distribution of topological isomers

21 January 2018

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Interfacial inhibition of macromolecular interactions: nature's paradigm for drug discovery

21 January 2018

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Topoisomerase I inhibitors: camptothecins and beyond

21 January 2018

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Equilibrium distributions of topological states in circular DNA: interplay of supercoiling and knotting

21 January 2018

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The structure of supercoiled intermediates in DNA replication

21 January 2018

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Structure of a Complex between E. coli DNA Topoisomerase I and Single-Stranded DNA

21 January 2018

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The geometry of DNA supercoils modulates topoisomerase-mediated DNA cleavage and enzyme response to anticancer drugs

21 January 2018

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Biochemical characterization of an invariant histidine involved in Escherichia coli DNA topoisomerase I catalysis.

21 January 2018

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Ability of viral topoisomerase II to discern the handedness of supercoiled DNA: bimodal recognition of DNA geometry by type II enzymes

21 January 2018

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Structural Basis for Specificity in the Poxvirus Topoisomerase

21 January 2018

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The ATP-binding site of type II topoisomerases as a target for antibacterial drugs

21 January 2018

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Coupling ATP hydrolysis to DNA strand passage in type IIA DNA topoisomerases.

21 January 2018

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SUMO-1 conjugation to human DNA topoisomerase II isozymes

21 January 2018

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https://api.crossref.org/works/10.1017/S003358350800468X

Protist homologs of the meiotic Spo11 gene and topoisomerase VI reveal an evolutionary history of gene duplication and lineage-specific loss

21 January 2018

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BRCA1 participates in DNA decatenation

21 January 2018

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A role for topoisomerase III in a recombination pathway alternative to RuvABC.

21 January 2018

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Supercoiling of the DNA template during transcription

21 January 2018

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The interaction of Escherichia coli topoisomerase IV with DNA.

21 January 2018

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Decatenation activity of topoisomerase IV during oriC and pBR322 DNA replication in vitro

21 January 2018

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Crystal structure of a bacterial type IB DNA topoisomerase reveals a preassembled active site in the absence of DNA.

21 January 2018

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Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

21 January 2018

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Evidence for a conformational change in the DNA gyrase-DNA complex from hydroxyl radical footprinting

21 January 2018

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DNA-DNA gyrase complex: the wrapping of the DNA duplex outside the enzyme

21 January 2018

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Dissection of the bacteriophage Mu strong gyrase site (SGS): significance of the SGS right arm in Mu biology and DNA gyrase mechanism

21 January 2018

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T4 DNA topoisomerase: a new ATP-dependent enzyme essential for initiation of T4 bacteriophage DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Characterization of a unique type IA topoisomerase in Bacillus cereus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

DNA gyrase and topoisomerase IV: biochemical activities, physiological roles during chromosome replication, and drug sensitivities

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Topoisomerase II from Chlorella virus PBCV-1. Characterization of the smallest known type II topoisomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

An open conformation of the Thermus thermophilus gyrase B ATP-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Modulation of human DNA topoisomerase IIalpha function by interaction with 14-3-3epsilon

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Proton relay mechanism of general acid catalysis by DNA topoisomerase IB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

A poxvirus-like type IB topoisomerase family in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Catalytic mechanism of DNA topoisomerase IB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Effect of 2'-5' phosphodiesters on DNA transesterification by vaccinia topoisomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

The "GyrA-box" is required for the ability of DNA gyrase to wrap DNA and catalyze the supercoiling reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

DNA enzymology above 100 degrees C. Topoisomerase V unlinks circular DNA at 80-122 degrees C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

New topoisomerase essential for chromosome segregation in E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Conversion of DNA gyrase into a conventional type II topoisomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

A model for the mechanism of strand passage by DNA gyrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Reverse gyrase has heat-protective DNA chaperone activity independent of supercoiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Evolutionary history and higher order classification of AAA ATPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

DNA topoisomerase II interacts with Lim15/Dmc1 in meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

The Role of Lysine 532 in the Catalytic Mechanism of Human Topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Phylogenomics of type II DNA topoisomerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

The key DNA-binding residues in the C-terminal domain of Mycobacterium tuberculosis DNA gyrase A subunit (GyrA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Origin and evolution of DNA topoisomerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Conformational changes in E. coli DNA topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Protein-nucleotide interactions in E. coli DNA topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

A physical and functional interaction between Escherichia coli FtsK and topoisomerase IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Bacterial diversity based on type II DNA topoisomerase genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Reverse gyrase functions as a DNA renaturase: annealing of complementary single-stranded circles and positive supercoiling of a bubble substrate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Nucleotide- and stoichiometry-dependent DNA supercoiling by reverse gyrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Drosophila topoisomerase II-DNA interactions are affected by DNA structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

GHKL, an emergent ATPase/kinase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Closing the ring: links between SMC proteins and chromosome partitioning, condensation, and supercoiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Control of bacterial DNA supercoiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Structural basis for gate-DNA recognition and bending by type IIA topoisomerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Mechanistic studies on E. coli DNA topoisomerase I: divalent ion effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Nucleotide binding to DNA gyrase causes loss of DNA wrap

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Topoisomerase II: A specific marker for cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Molecular characterization of homologues of both subunits A (SPO11) and B of the archaebacterial topoisomerase 6 in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

DNA recognition by proteins with the helix-turn-helix motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

RecQ helicase and topoisomerase III comprise a novel DNA strand passage function: a conserved mechanism for control of DNA recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Impact of the C-terminal domain of topoisomerase IIalpha on the DNA cleavage activity of the human enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

DNA topoisomerases I and II in human mature sperm cells: characterization and unique properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Conformational fluctuations of DNA helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

The mechanism of type IA topoisomerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Hin-mediated DNA knotting and recombining promote replicon dysfunction and mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Reverse gyrase, the two domains intimately cooperate to promote positive supercoiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

The structure of the transition state of the heterodimeric topoisomerase I of Leishmania donovani as a vanadate complex with nicked DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Molecular basis of gyrase poisoning by the addiction toxin CcdB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Crystal Structure of Full Length Topoisomerase I from Thermotoga maritima

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Protein footprinting by the combined use of reversible and irreversible lysine modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Two tricks in one bundle: helix-turn-helix gains enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Dissection of the nucleotide cycle of B. subtilis DNA gyrase and its modulation by DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Mechanochemical analysis of DNA gyrase using rotor bead tracking

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

WebLogo: A Sequence Logo Generator

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

DNA gyrase: an enzyme that introduces superhelical turns into DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

21 January 2018

Winged helix proteins

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Preferential relaxation of positively supercoiled DNA by E. coli topoisomerase IV in single-molecule and ensemble measurements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Linking numbers and nucleosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

E. coli integration host factor binds to specific sites in DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Small-angle X-ray scattering reveals the solution structure of the full-length DNA gyrase a subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

The structural basis for substrate specificity in DNA topoisomerase IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Structural dissection of ATP turnover in the prototypical GHL ATPase TopoVI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Structure, molecular mechanisms, and evolutionary relationships in DNA topoisomerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Structure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Emerging roles for plant topoisomerase VI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Holoenzyme assembly and ATP-mediated conformational dynamics of topoisomerase VI

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Mechanisms of camptothecin resistance by human topoisomerase I mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Role of the linker domain and the 203-214 N-terminal residues in the human topoisomerase I DNA complex dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Effect on DNA relaxation of the single Thr718Ala mutation in human topoisomerase I: a functional and molecular dynamics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Helical periodicity of DNA determined by enzyme digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Antitumour drugs impede DNA uncoiling by topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Reverse gyrase—a topoisomerase which introduces positive superhelical turns into DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

Self-Linking and the Gauss Integral in Higher Dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Asymmetric removal of supercoils suggests how topoisomerase II simplifies DNA topology

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Chemical and traditional mutagenesis of vaccinia DNA topoisomerase provides insights to cleavage site recognition and transesterification chemistry

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Structure of the topoisomerase IV C-terminal domain: a broken beta-propeller implies a role as geometry facilitator in catalysis

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

An atypical type II topoisomerase from Mycobacterium smegmatis with positive supercoiling activity

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Widespread distribution of archaeal reverse gyrase in thermophilic bacteria suggests a complex history of vertical inheritance and lateral gene transfers

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Essential mitotic functions of DNA topoisomerase IIalpha are not adopted by topoisomerase IIbeta in human H69 cells

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

The bacterial chromosome and its manner of replication as seen by autoradiography

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Communication between the ATPase and cleavage/religation domains of human topoisomerase IIalpha

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Kinetic proofreading can explain the supression of supercoiling of circular DNA molecules by type-II topoisomerases

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

An orphan gyrB in the Mycobacterium smegmatis genome uncovered by comparative genomics

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Coumarin and quinolone action in archaebacteria: evidence for the presence of a DNA gyrase-like enzyme

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

In vitro catenation and decatenation of DNA and a novel eucaryotic ATP-dependent topoisomerase

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Catalysis of ATP hydrolysis by two NH(2)-terminal fragments of yeast DNA topoisomerase II

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Pre-steady-state analysis of ATP hydrolysis by Saccharomyces cerevisiae DNA topoisomerase II. 2. Kinetic mechanism for the sequential hydrolysis of two ATP

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

C-terminal domains of Escherichia coli topoisomerase I belong to the zinc-ribbon superfamily

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

ATP-dependent DNA topoisonmerase from D. melanogaster reversibly catenates duplex DNA rings

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

DNA transport by a type II DNA topoisomerase: evidence in favor of a two-gate mechanism

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

The interaction of the F plasmid killer protein, CcdB, with DNA gyrase: induction of DNA cleavage and blocking of transcription 1 1J. Karn

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

A universal type IA topoisomerase fold

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Identification of a unique domain essential for Escherichia coli DNA topoisomerase III-catalysed decatenation of replication intermediates

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Adenosine 5'-O-(3-thio)triphosphate (ATPgammaS) promotes positive supercoiling of DNA by T. maritima reverse gyrase

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

C-terminal domain of gyrase A is predicted to have a beta-propeller structure

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Unraveling the mechanistic details of topoisomerases

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Physiological regulation of eukaryotic topoisomerase II

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Pre-steady-state analysis of ATP hydrolysis by Saccharomyces cerevisiae DNA topoisomerase II. 1. A DNA-dependent burst in ATP hydrolysis

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Steady-state and rapid kinetic analysis of topoisomerase II trapped as the closed-clamp intermediate by ICRF-193

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Bacterial DNA topoisomerase I can relax positively supercoiled DNA containing a single-stranded loop

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Roles of topoisomerases in maintaining steady-state DNA supercoiling in Escherichia coli

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Identification of DNA Gyrase Inhibitor (GyrI) inEscherichia coli

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Catalytic inhibitors of DNA topoisomerase II

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Reverse gyrase, a hallmark of the hyperthermophilic archaebacteria

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Escherichia coli DNA topoisomerase III: purification and characterization of a new type I enzyme

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Extreme resistance to thermally induced DNA backbone breaks in the hyperthermophilic archaeon Pyrococcus furiosus.

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

Vaccinia DNA topoisomerase I: evidence supporting a free rotation mechanism for DNA supercoil relaxation

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

The acidic triad conserved in type IA DNA topoisomerases is required for binding of Mg(II) and subsequent conformational change

1 reference

https://api.crossref.org/works/10.1017/S003358350800468X

7 January 2021

10.1017/S003358350800468X

Identifiers

DOI

1 reference

19 August 2017

1 reference