8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1. (Q37227596)

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29 February 2020

title

8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1 (English)

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29 February 2020

2

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Leopoldo Aguilera-aguirre

29 February 2020

3

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29 February 2020

Muralidhar L. Hegde

4

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29 February 2020

Zsolt Radak

7

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29 February 2020

Xueqing Ba

8

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9

Istvan Boldogh

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29 February 2020

6

Sanjiv Sur

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1

Gyorgy Hajas

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29 February 2020

author name string

K Hazra Tapas

5

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publication date

21 April 2013

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Free Radical Biology and Medicine

29 February 2020

published in

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volume

61

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29 February 2020

page(s)

384-394

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Perinuclear mitochondrial clustering creates an oxidant-rich nuclear domain required for hypoxia-induced transcription

29 February 2020

cites work

1 reference

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Mechanism of release and fate of excised oligonucleotides during nucleotide excision repair

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Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine

6 September 2017

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Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base

6 September 2017

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8-Oxoguanine-DNA glycosylase 1 deficiency modifies allergic airway inflammation by regulating STAT6 and IL-4 in cells and in mice

6 September 2017

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6 September 2017

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Direct visualization of repair of oxidative damage by OGG1 in the nuclei of live cells

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6 September 2017

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The Rho/Rac exchange factor Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells.

6 September 2017

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Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme

6 September 2017

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Nox-4-dependent nuclear H2O2 drives DNA oxidation resulting in 8-OHdG as urinary biomarker and hemangioendothelioma formation

6 September 2017

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Mitochondrial dysfunction increases allergic airway inflammation

6 September 2017

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Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis

6 September 2017

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Formamidopyrimidines in DNA: mechanisms of formation, repair, and biological effects

6 September 2017

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Many faces of Ras activation

6 September 2017

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Increased ROS generation in subsets of OGG1 knockout fibroblast cells

6 September 2017

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Quantitative colocalization analysis of multicolor confocal immunofluorescence microscopy images: pushing pixels to explore biological phenomena

6 September 2017

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ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis

6 September 2017

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Regulation of Nox and Duox enzymatic activity and expression

6 September 2017

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Base-excision repair of oxidative DNA damage

6 September 2017

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OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo

6 September 2017

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6 September 2017

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Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases

6 September 2017

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Choreography of oxidative damage repair in mammalian genomes

6 September 2017

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Human OGG1 undergoes serine phosphorylation and associates with the nuclear matrix and mitotic chromatin in vivo

6 September 2017

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Involvement of mammalian OGG1(MMH) in excision of the 8-hydroxyguanine residue in DNA.

6 September 2017

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 September 2017

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Assay of Cdc42, Rac, and Rho GTPase activation by affinity methods.

6 September 2017

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DNA glycosylases: specificity and mechanisms

6 September 2017

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Measurement of 8-hydroxy-2'-deoxyguanosine in DNA by high-performance liquid chromatography-mass spectrometry: comparison with measurement by gas chromatography-mass spectrometry

6 September 2017

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Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice

6 September 2017

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Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

6 September 2017

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The structural basis of the activation of Ras by Sos

6 September 2017

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6 September 2017

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DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression

6 September 2017

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14 September 2017

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14 September 2017

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The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways

28 September 2017

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Features of systemic lupus erythematosus in Dnase1-deficient mice

28 September 2017

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CDC25(Mm)/Ras-GRF1 regulates both Ras and Rac signaling pathways

26 June 2018

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Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation

26 June 2018

1 reference

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Age-dependent modulation of DNA repair enzymes by covalent modification and subcellular distribution

3 September 2018

1 reference

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Cell cycle regulation of the murine 8-oxoguanine DNA glycosylase (mOGG1): mOGG1 associates with microtubules during interphase and mitosis

3 September 2018

1 reference

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Comparative functional analysis of the Rac GTPases

3 September 2018

1 reference

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Genetically encoded fluorescent indicator for intracellular hydrogen peroxide

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23612479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of Mg2 cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23612479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

8-oxo-7,8-dihydroguanosine triphosphate(8-oxoGTP) down-regulates respiratory burst of neutrophils by antagonizing GTP toward Rac, a small GTP binding protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23612479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.FREERADBIOMED.2013.04.011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23612479 AND SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23612479 AND SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

23612479

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23612479 AND SRC:MED&resulttype=core&format=json