Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice (Q37219834)

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scientific article published on 21 June 2016

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English	Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice	scientific article published on 21 June 2016

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scholarly article

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Europe PubMed Central

PMC publication ID

19 August 2017

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice (English)

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Europe PubMed Central

PMC publication ID

19 August 2017

type 2 diabetes

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0 references

Vacuolar protein sorting 13C

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GOA release 2020-03-11

glucose intolerance

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based on heuristic

inferred from title

Zenobia B Mehta

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27329800 AND SRC:MED&resulttype=core&format=json

9 June 2020

2

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9 June 2020

Timothy J Pullen

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9 June 2020

Antonio Velayos-Baeza

8

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9 June 2020

Lorella Marselli

10

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9 June 2020

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9 June 2020

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Matthew C Cane

4

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9 June 2020

Ming Hu

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9 June 2020

Pauline Chabosseau

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9 June 2020

Gargi Meur

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9 June 2020

Anthony P Monaco

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Piero Marchetti

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9 June 2020

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21 June 2016

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19 August 2017

American Journal of Physiology - Endocrinology and Metabolism

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9 June 2020

311

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9 June 2020

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9 June 2020

E488-507

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9 June 2020

describes a project that uses

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11 June 2022

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Identification of VPS13C as a Galectin-12-Binding Protein That Regulates Galectin-12 Protein Stability and Adipogenesis

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p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion.

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Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy

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Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors

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TipC and the chorea-acanthocytosis protein VPS13A regulate autophagy in Dictyostelium and human HeLa cells

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The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression.

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Chorein, the protein responsible for chorea-acanthocytosis, interacts with β-adducin and β-actin.

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SPO71 encodes a developmental stage-specific partner for Vps13 in Saccharomyces cerevisiae

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VPS13 regulates membrane morphogenesis during sporulation in Saccharomyces cerevisiae

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Subcellular localization and putative role of VPS13A/chorein in dopaminergic neuronal cells

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Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

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Cohen syndrome-associated protein, COH1, is a novel, giant Golgi matrix protein required for Golgi integrity

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A Genome-Wide Association Study Confirms Previously Reported Loci for Type 2 Diabetes in Han Chinese

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Effects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children

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Vacuolar protein sorting protein 13A, TtVPS13A, localizes to the tetrahymena thermophila phagosome membrane and is required for efficient phagocytosis

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Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes

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Joint effect of insulin signaling genes on insulin secretion and glucose homeostasis.

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The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals

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In vivo distribution and localization of chorein

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Association Analysis of 6,736 U.K. Subjects Provides Replication and ConfirmsTCF7L2as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00074.2016

21 January 2018

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00074.2016

21 January 2018

Variant of Transcription Factor 7-Like 2 (TCF7L2) Gene and the Risk of Type 2 Diabetes in Large Cohorts of U.S. Women and Men

1 reference

https://api.crossref.org/works/10.1152/AJPENDO.00074.2016

21 January 2018

Chorein-sensitive polymerization of cortical actin and suicidal cell death in chorea-acanthocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27329800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular retention of newly synthesized insulin in yeast is caused by endoproteolytic processing in the Golgi complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/27329800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPENDO.00074.2016

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27329800 AND SRC:MED&resulttype=core&format=json

9 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27329800 AND SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27329800 AND SRC:MED&resulttype=core&format=json

9 June 2020

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