Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. (Q37188424)

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21 March 2020

title

Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs (English)

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3

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Tomohiro Kayama

5

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Daisuke Sakai

12

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author name string

Ryo Nakamichi

1

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Yoshiaki Ito

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Naoko Onizuka

4

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Kensuke Kataoka

6

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Hidetsugu Suzuki

7

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Masaki Mori

8

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Masayo Inagawa

9

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Shizuko Ichinose

10

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Martin K Lotz

11

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Koichi Masuda

13

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Toshifumi Ozaki

14

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Hiroshi Asahara

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language of work or name

English

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publication date

16 August 2016

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21 March 2020

published in

Nature Communications

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volume

7

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page(s)

12503

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Creative Commons Attribution 4.0 International

21 March 2020

copyright license

start time

16 August 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Gtf2ird1-Dependent Mohawk Expression Regulates Mechanosensing Properties of the Tendon

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Mohawk promotes the tenogenesis of mesenchymal stem cells through activation of the TGFβ signaling pathway

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Transcription factor EGR1 directs tendon differentiation and promotes tendon repair

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Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation

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Foxa1 and Foxa2 are required for formation of the intervertebral discs

6 September 2017

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Changes in the molecular phenotype of nucleus pulposus cells with intervertebral disc aging

6 September 2017

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Challenges and strategies in the repair of ruptured annulus fibrosus

6 September 2017

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BMP-2 and TGF-β3 do not prevent spontaneous degeneration in rabbit disc explants but induce ossification of the annulus fibrosus

6 September 2017

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Intervertebral Disk Repair by Protein, Gene, or Cell Injection: A Framework for Rehabilitation‐Focused Biologics in the Spine

6 September 2017

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Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs

6 September 2017

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The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis

6 September 2017

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The Mohawk homeobox gene is a critical regulator of tendon differentiation

6 September 2017

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Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc

6 September 2017

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6 September 2017

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A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58

6 September 2017

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Absence of biglycan accelerates the degenerative process in mouse intervertebral disc

6 September 2017

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Postnatal growth, differentiation, and aging of the mouse intervertebral disc

6 September 2017

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Repair, regenerative and supportive therapies of the annulus fibrosus: achievements and challenges

6 September 2017

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Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation

6 September 2017

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Adipose stem cells for intervertebral disc regeneration: current status and concepts for the future.

6 September 2017

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Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons

6 September 2017

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The cost-utility of lumbar disc herniation surgery

6 September 2017

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Osteogenic protein-1 injection into a degenerated disc induces the restoration of disc height and structural changes in the rabbit anular puncture model

6 September 2017

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Mohawk is a novel homeobox gene expressed in the developing mouse embryo

6 September 2017

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Growth factors and treatment of intervertebral disc degeneration

6 September 2017

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Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

6 September 2017

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The notochordal cell in the nucleus pulposus: a review in the context of tissue engineering

6 September 2017

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6 September 2017

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6 September 2017

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1 reference

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6 September 2017

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14 September 2017

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Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration

28 September 2017

1 reference

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Link N and mesenchymal stem cells can induce regeneration of the early degenerate intervertebral disc

26 June 2018

1 reference

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The effect of Link N on differentiation of human bone marrow-derived mesenchymal stem cells

26 June 2018

1 reference

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Anular delamination strength of human lumbar intervertebral disc

26 June 2018

1 reference

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26 June 2018

1 reference

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Type XIV Collagen Regulates Fibrillogenesis: PREMATURE COLLAGEN FIBRIL GROWTH AND TISSUE DYSFUNCTION IN NULL MICE.

26 June 2018

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Types I and II collagens in intervertebral disc. Interchanging radial distributions in annulus fibrosus

26 June 2018

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Intervertebral disc repair with activated nucleus pulposus cell transplantation: a three-year, prospective clinical study of its safety.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990710

A combined biomaterial and cellular approach for annulus fibrosus rupture repair.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990710

Migration of bone marrow-derived cells for endogenous repair in a new tail-looping disc degeneration model in the mouse: a pilot study

3 September 2018

1 reference

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Modulation of annulus fibrosus cell alignment and function on oriented nanofibrous polyurethane scaffolds under tension.

3 September 2018

1 reference

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Scx /Sox9 progenitors contribute to the establishment of the junction between cartilage and tendon/ligament

3 September 2018

1 reference

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Cartilage tissue enhances proteoglycan retention by nucleus pulposus cells in vitro

3 September 2018

1 reference

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Intercellular signaling pathways active during intervertebral disc growth, differentiation, and aging

3 September 2018

1 reference

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3 September 2018

1 reference

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3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990710

Sox9 is required for notochord maintenance in mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990710

Regenerative effects of transplanting mesenchymal stem cells embedded in atelocollagen to the degenerated intervertebral disc

3 September 2018

1 reference

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The effect of bone morphogenetic protein-2 on rat intervertebral disc cells in vitro

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990710

Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990710

Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4990710

Changes in mRNA and protein levels of proteoglycans of the anulus fibrosus and nucleus pulposus during intervertebral disc degeneration

3 September 2018

1 reference

12 December 2020

Immunohistochemical localization of the small proteoglycans decorin and biglycan in human intervertebral discs

1 reference

12 December 2020

Percutaneous reinsertion of the nucleus pulposus. An experimental study

1 reference

12 December 2020

Mesenchymal stem cells reduce intervertebral disc fibrosis and facilitate repair

1 reference

12 December 2020

Vertebral osteophyte formation in experimental disc degeneration. Morphologic and proteoglycan changes over time

1 reference

12 December 2020

Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS12503

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27527664 AND SRC:MED&resulttype=core&format=json

21 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27527664 AND SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

27527664

1 reference