Emerging targets in pancreatic cancer: epithelial-mesenchymal transition and cancer stem cells (Q37178822)

18 August 2017

Emerging targets in pancreatic cancer: epithelial-mesenchymal transition and cancer stem cells (English)

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18 August 2017

neoplastic stem cells

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3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24049451 AND SRC:MED&resulttype=core&format=json

14 June 2020

author name string

Jason A Castellanos

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24049451 AND SRC:MED&resulttype=core&format=json

14 June 2020

Nipun B Merchant

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24049451 AND SRC:MED&resulttype=core&format=json

14 June 2020

language of work or name

English

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publication date

13 September 2013

1 reference

18 August 2017

OncoTargets and Therapy

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24049451 AND SRC:MED&resulttype=core&format=json

14 June 2020

volume

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24049451 AND SRC:MED&resulttype=core&format=json

14 June 2020

page(s)

1261-1267

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24049451 AND SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

14 June 2020

copyright license

start time

1 September 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Targeted Inhibition of Src Kinase Signaling Attenuates Pancreatic Tumorigenesis

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6 September 2017

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Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

6 September 2017

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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The epithelial-mesenchymal transition generates cells with properties of stem cells

6 September 2017

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Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

6 September 2017

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CD133 expression is correlated with lymph node metastasis and vascular endothelial growth factor-C expression in pancreatic cancer

6 September 2017

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Up-regulation of MSX2 enhances the malignant phenotype and is associated with twist 1 expression in human pancreatic cancer cells

6 September 2017

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Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin

6 September 2017

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Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression

6 September 2017

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Epithelial--mesenchymal and mesenchymal--epithelial transitions in carcinoma progression.

6 September 2017

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Cancer stem cell: target for anti-cancer therapy

6 September 2017

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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

6 September 2017

1 reference

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Identification of pancreatic cancer stem cells

6 September 2017

1 reference

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The determinant factors of recurrence following resection for ductal pancreatic cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

6 September 2017

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Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Identification of bronchioalveolar stem cells in normal lung and lung cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Wnt, hedgehog and snail: sister pathways that control by GSK-3beta and beta-Trcp in the regulation of metastasis

6 September 2017

1 reference

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ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma

6 September 2017

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6 September 2017

AC133/CD133/Prominin-1

1 reference

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The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Identification of a cancer stem cell in human brain tumors

6 September 2017

1 reference

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

6 September 2017

1 reference

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Prospective identification of tumorigenic breast cancer cells

6 September 2017

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6 September 2017

The Hallmarks of Cancer

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CD24, a mucin-type glycoprotein, is a ligand for P-selectin on human tumor cells

6 September 2017

1 reference

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Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule

6 September 2017

1 reference

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Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Silibinin reverses epithelial-to-mesenchymal transition in metastatic prostate cancer cells by targeting transcription factors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Hypoxia-inducible factor-1alpha induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Periostin, secreted from stromal cells, has biphasic effect on cell migration and correlates with the epithelial to mesenchymal transition of human pancreatic cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Expression of snail in pancreatic cancer promotes metastasis and chemoresistance

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Identification and characterization of tumorigenic liver cancer stem/progenitor cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Expression of CD44 confers a new adhesive phenotype on transfected cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Stem cell gene expression programs influence clinical outcome in human leukemia.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Epithelial to mesenchymal transition: expression of the regulators snail, slug, and twist in pancreatic cancer.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775701

Overexpression and activation of the tyrosine kinase Src in human pancreatic carcinoma

3 September 2018

1 reference

12 December 2020

Patterns of failure after curative resection of pancreatic carcinoma

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12 December 2020

Expression of E-cadherin and uPA and their association with the prognosis of pancreatic cancer

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12 December 2020

Heparan Sulfate-modified CD44 Promotes Hepatocyte Growth Factor/Scatter Factor-induced Signal Transduction through the Receptor Tyrosine Kinase c-Met

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12 December 2020

c-Met is a marker of pancreatic cancer stem cells and therapeutic target

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12 December 2020

Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines and in prostate cancer specimens

1 reference

12 December 2020

Identifiers

DOI

10.2147/OTT.S34670

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24049451 AND SRC:MED&resulttype=core&format=json

14 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24049451 AND SRC:MED&resulttype=core&format=json

14 June 2020

PubMed publication ID

24049451

1 reference