Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry (Q37169659)

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28 February 2020

title

Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry (English)

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28 February 2020

1

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28 February 2020

author name string

Piotr J Mak

series ordinal

2

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28 February 2020

Stephen G Sligar

series ordinal

3

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28 February 2020

James R Kincaid

series ordinal

4

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28 February 2020

language of work or name

English

0 references

publication date

10 April 2013

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Angewandte Chemie International Edition

28 February 2020

published in

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28 February 2020

volume

52

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28 February 2020

issue

20

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28 February 2020

page(s)

5342-5345

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CO, NO and O2 as Vibrational Probes of Heme Protein Interactions

28 February 2020

cites work

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Defining CYP3A4 Structural Responses to Substrate Binding. Raman Spectroscopic Studies of a Nanodisc-Incorporated Mammalian Cytochrome P450

6 September 2017

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A review of mechanistic studies on aromatase (CYP19) and 17α-hydroxylase-17,20-lyase (CYP17)

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At the crossroads of steroid hormone biosynthesis: the role, substrate specificity and evolutionary development of CYP17.

6 September 2017

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Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscs

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Membrane protein assembly into Nanodiscs

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Resonance Raman characterization of the peroxo and hydroperoxo intermediates in cytochrome P450.

6 September 2017

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The ferrous-oxy complex of human aromatase

6 September 2017

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Basic concepts and recent developments in human steroid hormone biosynthesis

6 September 2017

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Structure and chemistry of cytochrome P450.

6 September 2017

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Mechanism of oxidation reactions catalyzed by cytochrome p450 enzymes.

6 September 2017

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An analysis of the role of active site protic residues of cytochrome P-450s: mechanistic and mutational studies on 17α-hydroxylase-17,20-lyase (P-45017α also CYP17)

6 September 2017

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Cytochrome b 5 Augments the 17,20-Lyase Activity of Human P450c17 without Direct Electron Transfer

6 September 2017

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Rat P450(17 alpha) from testis: characterization of a full-length cDNA encoding a unique steroid hydroxylase capable of catalyzing both delta 4- and delta 5-steroid-17,20-lyase reactions

6 September 2017

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Modulation of the activity of human 17 alpha-hydroxylase-17,20-lyase (CYP17) by cytochrome b5: endocrinological and mechanistic implications

6 September 2017

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Interaction between substrate and oxygen ligand responsible for effective O-O bond cleavage in bovine cytochrome P450 steroid 21-hydroxylase proved by Raman spectroscopy

27 June 2018

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Substrate- and isoform-specific dioxygen complexes of nitric oxide synthase.

3 September 2018

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Nitrosyl-heme structures of Bacillus subtilis nitric oxide synthase have implications for understanding substrate oxidation

3 September 2018

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Second half-reaction of nitric oxide synthase: computational insights into the initial step and key proposed intermediate

3 September 2018

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Molecular dynamics of substrate complexes with hamster cytochrome P450c17 (CYP17): mechanistic approach to understanding substrate binding and activities

3 September 2018

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Searching for the second oxidant in the catalytic cycle of cytochrome P450: a theoretical investigation of the iron(III)-hydroperoxo species and its epoxidation pathways

3 September 2018

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Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: the effect of model membranes

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002/ANIE.201300760

Structural and functional properties of a truncated hemoglobin from a food-borne pathogen Campylobacter jejuni

21 January 2018

1 reference

12 December 2020

Expression and purification of functional human 17 alpha-hydroxylase/17,20-lyase (P450c17) in Escherichia coli. Use of this system for study of a novel form of combined 17 alpha-hydroxylase/17,20-lyase deficiency

1 reference

12 December 2020

Mechanism of the acyl-carbon cleavage and related reactions catalyzed by multifunctional P-450s: studies on cytochrome P-450(17)alpha

1 reference

12 December 2020

Substrate-specific Interactions with the Heme-bound Oxygen Molecule of Nitric-oxide Synthase

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12 December 2020

Identifiers

DOI

10.1002/ANIE.201300760

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23576395 AND SRC:MED&resulttype=core&format=json

release_acobp6jv7ner7de2tafoh6qjre

28 February 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/acobp6jv7ner7de2tafoh6qjre

24 November 2022

mapped directly with Wikidata item

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28 February 2020

PubMed publication ID

23576395

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