Live Attenuated Borrelia burgdorferi Targeted Mutants in an Infectious Strain Background Protect Mice from Challenge Infection (Q37163689)

18 August 2017

Live Attenuated Borrelia burgdorferi Targeted Mutants in an Infectious Strain Background Protect Mice from Challenge Infection (English)

1 reference

18 August 2017

0 references

0 references

1 reference

Beth L Hahn

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27335385 AND SRC:MED&resulttype=core&format=json

9 June 2020

Lavinia J Padmore

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27335385 AND SRC:MED&resulttype=core&format=json

9 June 2020

Michael W Curtis

series ordinal

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27335385 AND SRC:MED&resulttype=core&format=json

9 June 2020

publication date

22 June 2016

1 reference

Clinical and Vaccine Immunology

18 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27335385 AND SRC:MED&resulttype=core&format=json

9 June 2020

volume

23

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9 June 2020

issue

8

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9 June 2020

page(s)

725-731

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27335385 AND SRC:MED&resulttype=core&format=json

Epidemiology of Lyme disease

9 June 2020

cites work

1 reference

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6 September 2017

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A Novel multivalent OspA vaccine against Lyme borreliosis is safe and immunogenic in an adult population previously infected with Borrelia burgdorferi sensu lato

6 September 2017

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Reservoir targeted vaccine against Borrelia burgdorferi: a new strategy to prevent Lyme disease transmission

6 September 2017

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Oral vaccination with vaccinia virus expressing the tick antigen subolesin inhibits tick feeding and transmission of Borrelia burgdorferi

6 September 2017

1 reference

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The β₃-integrin ligand of Borrelia burgdorferi is critical for infection of mice but not ticks

6 September 2017

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The rise and fall of the lyme disease vaccines: a cautionary tale for risk interventions in American medicine and public health

6 September 2017

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Detection of established virulence genes and plasmids to differentiate Borrelia burgdorferi strains

6 September 2017

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Reservoir Targeted Vaccine for Lyme Borreliosis Induces a Yearlong, Neutralizing Antibody Response to OspA in White-Footed Mice

6 September 2017

1 reference

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Antiscience and ethical concerns associated with advocacy of Lyme disease

6 September 2017

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Development of a baited oral vaccine for use in reservoir-targeted strategies against Lyme disease

6 September 2017

1 reference

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Relationship between Immunity to Borrelia burgdorferi Outer-surface Protein A (OspA) and Lyme Arthritis

6 September 2017

1 reference

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Vaccines against Lyme Disease: What Happened and What Lessons Can We Learn?

6 September 2017

1 reference

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The Lyme Disease Vaccine—A Public Health Perspective

6 September 2017

1 reference

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Searching for borrelial T cell epitopes associated with antibiotic-refractory Lyme arthritis

6 September 2017

1 reference

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An Octavalent Lyme Disease Vaccine Induces Antibodies That Recognize All Incorporated ospC Type-Specific Sequences

6 September 2017

1 reference

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OspC phylogenetic analyses support the feasibility of a broadly protective polyvalent chimeric Lyme disease vaccine

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Construction and analysis of variants of a polyvalent Lyme disease vaccine: approaches for improving the immune response to chimeric vaccinogens.

6 September 2017

1 reference

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Protective efficacy of an oral vaccine to reduce carriage of Borrelia burgdorferi (strain N40) in mouse and tick reservoirs

6 September 2017

1 reference

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An ecological approach to preventing human infection: vaccinating wild mouse reservoirs intervenes in the Lyme disease cycle

6 September 2017

1 reference

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Essential role for OspA/B in the life cycle of the Lyme disease spirochete

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Targeted mutation of the outer membrane protein P66 disrupts attachment of the Lyme disease agent, Borrelia burgdorferi , to integrin α v β 3

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Borrelia burgdorferi population kinetics and selected gene expression at the host-vector interface

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Clonal polymorphism of Borrelia burgdorferi strain B31 MI: implications for mutagenesis in an infectious strain background

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Protection elicited by native outer membrane protein Oms66 (p66) against host-adapted Borrelia burgdorferi: conformational nature of bactericidal epitopes

6 September 2017

1 reference

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Characterization of a candidate Borrelia burgdorferi beta3-chain integrin ligand identified using a phage display library

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

The immunoglobulin (IgG) antibody response to OspA and OspB correlates with severe and prolonged Lyme arthritis and the IgG response to P35 correlates with mild and brief arthritis

6 September 2017

1 reference

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Active and Passive Immunity againstBorrelia burgdorferiDecorin Binding Protein A (DbpA) Protects against Infection

6 September 2017

1 reference

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Dominant recognition of a Borrelia burgdorferi outer surface protein A peptide by T helper cells in patients with treatment-resistant Lyme arthritis

6 September 2017

1 reference

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Chronic Lyme borreliosis in the laboratory mouse.

6 September 2017

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Induction of an outer surface protein on Borrelia burgdorferi during tick feeding

6 September 2017

1 reference

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Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi

6 September 2017

1 reference

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Isolation and cultivation of Lyme disease spirochetes

6 September 2017

1 reference

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Active immunization of hamsters against experimental infection with Borrelia burgdorferi

6 September 2017

1 reference

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Binding of cultured mammalian cells to immobilized bacteria

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Demonstration of OspC type diversity in invasive human lyme disease isolates and identification of previously uncharacterized epitopes that define the specificity of the OspC murine antibody response.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Immunological and molecular polymorphisms of OspC, an immunodominant major outer surface protein of Borrelia burgdorferi.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Protection of dogs from Lyme disease with a vaccine containing outer surface protein (Osp) A, OspB, and the saponin adjuvant QS21.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Notes from the field: update on Lyme carditis, groups at high risk, and frequency of associated sudden cardiac death--United States.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Three sudden cardiac deaths associated with Lyme carditis - United States, November 2012-July 2013.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Multiplex PCR as a tool for validating plasmid content of Borrelia burgdorferi

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Development of an OspC-based tetravalent, recombinant, chimeric vaccinogen that elicits bactericidal antibody against diverse Lyme disease spirochete strains.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Experimental infection of Ixodes scapularis larvae (Acari: Ixodidae) by immersion in low passage cultures of Borrelia burgdorferi.

3 September 2018

1 reference

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A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease. Recombinant Outer-Surface Protein A Lyme Disease Vaccine Study Consortium

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979176

Association of antibiotic treatment-resistant Lyme arthritis with T cell responses to dominant epitopes of outer surface protein A of Borrelia burgdorferi

3 September 2018

1 reference

12 December 2020

A DNA vaccine encoding the outer surface protein C from Borrelia burgdorferi is able to induce protective immune responses

1 reference

12 December 2020

Vaccination of hamsters against experimental infection with Borrelia burgdorferi

1 reference

12 December 2020

A Flagella-less Mutant of Borrelia burgdorferi as a Live Attenuated Vaccine in the Murine Model of Lyme Disease

1 reference

12 December 2020

Multicomponent Lyme vaccine: three is not a crowd

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12 December 2020

Identifiers

DOI

10.1128/CVI.00302-16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27335385 AND SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27335385 AND SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

27335385

1 reference