Aging Shapes the Population-Mean and -Dispersion of Gene Expression in Human Brains (Q37147054)

18 August 2017

Aging Shapes the Population-Mean and -Dispersion of Gene Expression in Human Brains (English)

1 reference

18 August 2017

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27536236 AND SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Candice L Brinkmeyer-Langford

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27536236 AND SRC:MED&resulttype=core&format=json

12 June 2020

Jinting Guan

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27536236 AND SRC:MED&resulttype=core&format=json

12 June 2020

Guoli Ji

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27536236 AND SRC:MED&resulttype=core&format=json

12 June 2020

publication date

3 August 2016

1 reference

Frontiers in Aging Neuroscience

18 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27536236 AND SRC:MED&resulttype=core&format=json

12 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27536236 AND SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

183

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27536236 AND SRC:MED&resulttype=core&format=json

Epigenetic assimilation in the aging human brain

12 June 2020

cites work

1 reference

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Whole-Genome Sequencing of a Healthy Aging Cohort

6 September 2017

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Complement and microglia mediate early synapse loss in Alzheimer mouse models.

6 September 2017

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A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood.

6 September 2017

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Global genome splicing analysis reveals an increased number of alternatively spliced genes with aging

6 September 2017

1 reference

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IL7R gene expression network associates with human healthy ageing

6 September 2017

1 reference

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The transcriptional landscape of age in human peripheral blood

6 September 2017

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A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

6 September 2017

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Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

6 September 2017

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Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk

6 September 2017

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A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status

6 September 2017

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Coexpression networks identify brain region-specific enhancer RNAs in the human brain

6 September 2017

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Novel human ABCC9/SUR2 brain-expressed transcripts and an eQTL relevant to hippocampal sclerosis of aging

6 September 2017

1 reference

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Immune attack: the role of inflammation in Alzheimer disease.

6 September 2017

1 reference

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Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans

6 September 2017

1 reference

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Pathway-based factor analysis of gene expression data produces highly heritable phenotypes that associate with age.

6 September 2017

1 reference

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Aberrant gene expression in humans

6 September 2017

1 reference

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Transcriptional landscape of the prenatal human brain

6 September 2017

1 reference

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The developmental transcriptome of the human brain: implications for neurodevelopmental disorders

6 September 2017

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Additive, epistatic, and environmental effects through the lens of expression variability QTL in a twin cohort

6 September 2017

1 reference

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TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres

6 September 2017

1 reference

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A dramatic increase of C1q protein in the CNS during normal aging.

6 September 2017

1 reference

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Gene expression changes with age in skin, adipose tissue, blood and brain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Genetic variants contribute to gene expression variability in humans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Non-formalin fixative versus formalin-fixed tissue: a comparison of histology and RNA quality

6 September 2017

1 reference

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Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Spatio-temporal transcriptome of the human brain

6 September 2017

1 reference

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Rare and common regulatory variation in population-scale sequenced human genomes

6 September 2017

1 reference

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REVIGO summarizes and visualizes long lists of gene ontology terms

6 September 2017

1 reference

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A genome-wide association study of aging

6 September 2017

1 reference

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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

6 September 2017

1 reference

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Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

6 September 2017

1 reference

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Joint genetic analysis of gene expression data with inferred cellular phenotypes

6 September 2017

1 reference

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Chromatin structure as a mediator of aging

6 September 2017

1 reference

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Genetic variability in CLU and its association with Alzheimer's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Aging mice show a decreasing correlation of gene expression within genetic modules

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Age-dependent variability in gene expression in male Fischer 344 rat retina

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Functional organization of the transcriptome in human brain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Capturing heterogeneity in gene expression studies by surrogate variable analysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Intra-organ variation in age-related mutation accumulation in the mouse

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Genome dynamics and transcriptional deregulation in aging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Increased cell-to-cell variation in gene expression in ageing mouse heart

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

ON THE NATURE OF THE AGING PROCESS

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Distance-based tests for homogeneity of multivariate dispersions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Aging and gene expression in the primate brain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Rates of divergence in gene expression profiles of primates, mice, and flies: stabilizing selection and variability among functional categories.

6 September 2017

1 reference

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Impact of genome instability on transcription regulation of aging and senescence

6 September 2017

1 reference

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Gene regulation and DNA damage in the ageing human brain

6 September 2017

1 reference

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TP73 allelic expression in human brain and allele frequencies in Alzheimer's disease

6 September 2017

1 reference

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A neutral model of transcriptome evolution

6 September 2017

1 reference

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DAVID: Database for Annotation, Visualization, and Integrated Discovery

6 September 2017

1 reference

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Activity of human monocytes in IgE antibody-dependent surveillance and killing of ovarian tumor cells.

6 September 2017

1 reference

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p73 is required for survival and maintenance of CNS neurons

6 September 2017

1 reference

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Structural organization of the human MS4A gene cluster on Chromosome 11q12.

6 September 2017

1 reference

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Glutamatergic neurotransmission in aging: a critical perspective.

6 September 2017

1 reference

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An anti-apoptotic role for the p53 family member, p73, during developmental neuron death

6 September 2017

1 reference

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Inflammation and Alzheimer's disease

6 September 2017

1 reference

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p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

6 September 2017

1 reference

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The cholinergic hypothesis of Alzheimer's disease: a review of progress

6 September 2017

1 reference

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Protein Oxidation in Aging, Disease, and Oxidative Stress

6 September 2017

1 reference

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Alzheimer's disease: cell-specific pathology isolates the hippocampal formation

6 September 2017

1 reference

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Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease

6 September 2017

1 reference

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Ageing and Parkinson's disease: substantia nigra regional selectivity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Role of free radicals in aging and disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Neuropathological classification of Huntington's disease

6 September 2017

1 reference

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Common GSAP promoter variant contributes to Alzheimer's disease liability

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Transcriptional instability is not a universal attribute of aging.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Biological mechanisms underlying the aging process.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971101

Incomplete penetrance of familial Alzheimer's disease in a pedigree with a novel presenilin-1 gene mutation

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.3389/FNAGI.2016.00183

A Fast Algorithm for the Minimum Covariance Determinant Estimator

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.3389/FNAGI.2016.00183

Gene expression becomes heterogeneous with age

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27536236

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Epistasis and destabilizing mutations shape gene expression variability in humans via distinct modes of action.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27536236

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Glutathione: in sickness and in health

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27536236

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FNAGI.2016.00183

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27536236 AND SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27536236 AND SRC:MED&resulttype=core&format=json

12 June 2020

PubMed publication ID

27536236

1 reference