Role of stearoyl-CoA desaturases in obesity and the metabolic syndrome (Q37144096)

18 August 2017

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title

Role of stearoyl-CoA desaturases in obesity and the metabolic syndrome (English)

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18 August 2017

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H E Popeijus

1

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18 August 2017

W H M Saris

series ordinal

2

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18 August 2017

R P Mensink

series ordinal

3

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18 August 2017

language of work or name

English

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publication date

22 April 2008

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International Journal of Obesity

18 August 2017

published in

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18 August 2017

volume

32

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18 August 2017

issue

7

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18 August 2017

page(s)

1076-1082

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Overweight and obesity: prevalence, consequences, and causes of a growing public health problem

18 August 2017

cites work

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The epidemiology of obesity

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Dietary energy density is associated with obesity and the metabolic syndrome in U.S. adults

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Regulation of gene expression by dietary fat.

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Substituting dietary saturated fat with polyunsaturated fat changes abdominal fat distribution and improves insulin sensitivity

21 January 2018

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Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study

21 January 2018

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Plasma fatty acid composition and incidence of coronary heart disease in middle aged adults: the Atherosclerosis Risk in Communities (ARIC) Study

21 January 2018

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Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation

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PGC-1alpha: a potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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Membrane topology of mouse stearoyl-CoA desaturase 1

21 January 2018

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Purification and properties of rat liver microsomal stearyl coenzyme A desaturase

21 January 2018

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Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats

21 January 2018

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C. elegans feeding defective mutants have shorter body lengths and increased autophagy

21 January 2018

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Cold-induced expression of delta 9-desaturase in carp by transcriptional and posttranslational mechanisms

21 January 2018

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Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissues

21 January 2018

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Stearoyl-CoA desaturase mRNA is transcribed from a single gene in the ovine genome.

21 January 2018

1 reference

The P-OLE1 gene of Pichia angusta encodes a delta 9-fatty acid desaturase and complements the ole1 mutation of Saccharomyces cerevisiae

21 January 2018

1 reference

Sequence analysis and characterization of FAR-17c, an androgen-dependent gene in the flank organs of hamsters

21 January 2018

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Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors

21 January 2018

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Scd3--a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin

21 January 2018

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Identification of mouse palmitoyl-coenzyme A Delta9-desaturase

21 January 2018

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Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development

21 January 2018

1 reference

Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites

21 January 2018

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Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates

21 January 2018

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Characterization of human SCD2, an oligomeric desaturase with improved stability and enzyme activity by cross-linking in intact cells

21 January 2018

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Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans

21 January 2018

1 reference

Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen.

21 January 2018

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Regulation of stearoyl-CoA desaturase-1 after central and peripheral nerve lesions

21 January 2018

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Eight histidine residues are catalytically essential in a membrane-associated iron enzyme, stearoyl-CoA desaturase, and are conserved in alkane hydroxylase and xylene monooxygenase

21 January 2018

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The evolution of desaturases

21 January 2018

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Control of fatty acid desaturation: a mechanism conserved from bacteria to humans.

21 January 2018

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Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: requirement of a conserved CCAAT cis-element

21 January 2018

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Cloning and characterization of the human stearoyl-CoA desaturase gene promoter: transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol

21 January 2018

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Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression

21 January 2018

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Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma

21 January 2018

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Effects of fenofibrate and insulin on the biosynthesis of unsaturated fatty acids in streptozotocin diabetic rats

21 January 2018

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Degradation of stearoyl-coenzyme A desaturase: endoproteolytic cleavage by an integral membrane protease

21 January 2018

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The N terminus of microsomal delta 9 stearoyl-CoA desaturase contains the sequence determinant for its rapid degradation

21 January 2018

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Ubiquitin-proteasome-dependent degradation of mammalian ER stearoyl-CoA desaturase.

21 January 2018

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Selective mutagenesis of lysyl residues leads to a stable and active form of delta 9 stearoyl-CoA desaturase

21 January 2018

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Degradation of Hepatic Stearyl CoA Δ9-Desaturase

21 January 2018

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A microsomal endopeptidase from liver that preferentially degrades stearoyl-CoA desaturase

21 January 2018

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A plasminogen-like protein selectively degrades stearoyl-CoA desaturase in liver microsomes

21 January 2018

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High stearoyl-CoA desaturase protein and activity levels in simian virus 40 transformed-human lung fibroblasts.

21 January 2018

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The role of desaturases in cold-induced lipid restructuring

21 January 2018

2 references

21 January 2018

7 January 2021

Characterization of delta 9 acyl-lipid desaturase homologues from Arabidopsis thaliana

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CHILLING SENSITIVITY IN PLANTS AND CYANOBACTERIA: The Crucial Contribution of Membrane Lipids

21 January 2018

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Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

21 January 2018

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The obesity-cancer link: lessons learned from a fatless mouse

21 January 2018

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Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma

21 January 2018

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Fatty acid synthase and cancer: new application of an old pathway

21 January 2018

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Inhibition of fatty acid synthase activity in prostate cancer cells by dutasteride

21 January 2018

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Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

21 January 2018

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Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

21 January 2018

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Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice

21 January 2018

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Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1.

21 January 2018

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Diet-induced changes in stearoyl-CoA desaturase 1 expression in obesity-prone and -resistant mice.

21 January 2018

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Effects of leptin, troglitazone, and dietary fat on stearoyl CoA desaturase

21 January 2018

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Regulation by carbohydrate and clofibric acid of palmitoyl-CoA chain elongation in the liver of rats

21 January 2018

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Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism

21 January 2018

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'Striking the Right Balance' in Targeting PPARgamma in the Metabolic Syndrome: Novel Insights from Human Genetic Studies

21 January 2018

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Mucor rouxiiΔ9-Desaturase Gene Is Transcriptionally Regulated during Cell Growth and by Low Temperature

21 January 2018

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Obesity is associated with increased risks of prostate cancer metastasis and death after initial cancer diagnosis in middle-aged men

21 January 2018

1 reference

Prevalence of overweight and obesity in the Netherlands

21 January 2018

1 reference

7 January 2021

Dietary energy density is associated with overweight status among 5 ethnic groups in the multiethnic cohort study

1 reference

7 January 2021

Daily physical activity counts vs structured activity counts in lean and overweight Dutch children

1 reference

7 January 2021

Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites

1 reference

7 January 2021

Differential expression of cold- and diet-specific genes encoding two carp liver delta 9-acyl-CoA desaturase isoforms

1 reference

7 January 2021

The temperature-dependent expression of the desaturase gene desA in Synechocystis PCC6803

1 reference

7 January 2021

Immunohistochemical detection of a fatty acid synthase (OA-519) as a predictor of progression of prostate cancer

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7 January 2021

Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro

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7 January 2021

Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity.

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7 January 2021

Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes

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7 January 2021

Identifiers

DOI

10.1038/IJO.2008.55

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Dimensions Publication ID

18 August 2017

1043089414

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