Oximes: inhibitors of human recombinant acetylcholinesterase. A structure-activity relationship (SAR) study (Q37139239)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23959117 AND SRC:MED&resulttype=core&format=json

7 March 2020

title

Oximes: inhibitors of human recombinant acetylcholinesterase. A structure-activity relationship (SAR) study (English)

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7 March 2020

1

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7 March 2020

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Kamil Kuca

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7 March 2020

Jana Zdarova Karasova

2

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7 March 2020

Jan Korabecny

3

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7 March 2020

Rafael Dolezal

4

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7 March 2020

Filip Zemek

5

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7 March 2020

Brian J Bennion

6

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7 March 2020

language of work or name

English

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publication date

16 August 2013

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International Journal of Molecular Sciences

7 March 2020

published in

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7 March 2020

volume

14

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7 March 2020

issue

8

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7 March 2020

page(s)

16882-16900

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Creative Commons Attribution 4.0 International

7 March 2020

copyright license

start time

16 August 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of [...]

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Analysis and comparison of 2D fingerprints: insights into database screening performance using eight fingerprint methods

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Entry of oximes into the brain: a review

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Current understanding of the application of pyridinium oximes as cholinesterase reactivators in treatment of organophosphate poisoning

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Organophosphates/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

UCSF Chimera--a visualization system for exploratory research and analysis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

A new and rapid colorimetric determination of acetylcholinesterase activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II

14 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

14 September 2017

https://api.crossref.org/works/10.3390/IJMS140816882

Conformational flexibility of the acetylcholinesterase tetramer suggested by x-ray crystallography

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

The reactivation by oximes and hydroxamic acids of cholinesterase inhibited by organo-phosphorus compounds

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Passive diffusion of acetylcholinesterase oxime reactivators through the blood-brain barrier: influence of molecular structure

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

A comparison of the ability of a new bispyridinium oxime--1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium)butane dibromide and currently used oximes to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Novel piperidinium and pyridinium agents as water-soluble acetylcholinesterase inhibitors for the reversal of neuromuscular blockade

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Definitive evidence for the acute sarin poisoning diagnosis in the Tokyo subway

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759941

Organophosphates⧸Nerve Agent Poisoning: Mechanism of Action, Diagnosis, Prophylaxis, And Treatment

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390/IJMS140816882

Diagnosis of Intoxication by the Organophosphate VX: Comparison Between an Electrochemical Sensor and Ellman´s Photometric Method.

21 January 2018

1 reference

Crossref

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Study proves Iraq used nerve gas

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1 reference

Crossref

https://api.crossref.org/works/10.3390/IJMS140816882

A powerful reactivator of alkylphosphate-inhibited acetylcholinesterase

21 January 2018

1 reference

12 December 2020

Reactivation of acetylcholinesterase inhibited by alkylphosphates

1 reference

12 December 2020

Limitation of the Ellman method: cholinesterase activity measurement in the presence of oximes

1 reference

12 December 2020

Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage – Implications for early Myasthenia gravis treatment

1 reference

12 December 2020

Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment

1 reference

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Identifiers

DOI

10.3390/IJMS140816882

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23959117 AND SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23959117 AND SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

23959117

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23959117 AND SRC:MED&resulttype=core&format=json