dofetilide (Q3712521)

Dofetilide (English)

3 October 2016

C₁₉H₂₇N₃O₅S₂

1 reference

Dofetilide (English)

19 November 2016

CN(CCC1=CC=C(C=C1)NS(=O)(=O)C)CCOC2=CC=C(C=C2)NS(=O)(=O)C

1 reference

World Health Organisation international non-proprietary name

Dofetilide (English)

19 November 2016

1 reference

14 February 2018

dofetilide (English)

1 reference

dofetilide (English)

medical condition treated

3 October 2016

2 references

13 December 2016

2 October 2018

atrial flutter

1 reference

2 October 2018

heart arrhythmia

1 reference

2 October 2018

heart disease

1 reference

significant drug interaction

2 October 2018

amiodarone

1 reference

High-priority drug–drug interactions for use in electronic health records

anagrelide

1 reference

High-priority drug–drug interactions for use in electronic health records

arsenic trioxide

1 reference

High-priority drug–drug interactions for use in electronic health records

astemizole

1 reference

High-priority drug–drug interactions for use in electronic health records

azithromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

bepridil

1 reference

High-priority drug–drug interactions for use in electronic health records

chloroquine

1 reference

High-priority drug–drug interactions for use in electronic health records

chlorpromazine

1 reference

High-priority drug–drug interactions for use in electronic health records

cisapride

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-citalopram

1 reference

High-priority drug–drug interactions for use in electronic health records

clarithromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

cocaine

1 reference

High-priority drug–drug interactions for use in electronic health records

disopyramide

1 reference

High-priority drug–drug interactions for use in electronic health records

domperidone

1 reference

High-priority drug–drug interactions for use in electronic health records

dronedarone

1 reference

High-priority drug–drug interactions for use in electronic health records

droperidol

1 reference

High-priority drug–drug interactions for use in electronic health records

erythromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

escitalopram

1 reference

High-priority drug–drug interactions for use in electronic health records

flecainide

1 reference

High-priority drug–drug interactions for use in electronic health records

halofantrine

1 reference

High-priority drug–drug interactions for use in electronic health records

haloperidol

1 reference

High-priority drug–drug interactions for use in electronic health records

ibutilide

1 reference

High-priority drug–drug interactions for use in electronic health records

mesoridazine

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-methadone

1 reference

High-priority drug–drug interactions for use in electronic health records

reference URL

https://www.drugs.com/drug-interactions/methadone-index.html

moxifloxacin

1 reference

High-priority drug–drug interactions for use in electronic health records

ondansetron

1 reference

High-priority drug–drug interactions for use in electronic health records

pentamidine

1 reference

High-priority drug–drug interactions for use in electronic health records

pimozide

1 reference

High-priority drug–drug interactions for use in electronic health records

probucol

1 reference

High-priority drug–drug interactions for use in electronic health records

procainamide

1 reference

High-priority drug–drug interactions for use in electronic health records

quinidine

1 reference

High-priority drug–drug interactions for use in electronic health records

sevoflurane

1 reference

High-priority drug–drug interactions for use in electronic health records

sotalol

1 reference

High-priority drug–drug interactions for use in electronic health records

sparfloxacin

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-sulpiride

1 reference

High-priority drug–drug interactions for use in electronic health records

terfenadine

1 reference

High-priority drug–drug interactions for use in electronic health records

thioridazine

1 reference

High-priority drug–drug interactions for use in electronic health records

legal status (medicine)

boxed warning

1 reference

reference URL

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

LiverTox likelihood score

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)

LiverTox toxicity likelihood category E

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Dofetilide

last update

15 September 2016

subject has role

potassium channel blocker

1 reference

InChI=1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3

Medical Subject Headings

15 March 2018

1 reference

Medical Subject Headings

15 March 2018

Dofetilide

0 references

Identifiers

InChI

1 reference

Dofetilide (English)

19 November 2016

2 references

Dofetilide (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

115256-11-6

2 references

dofetilide (English)

19 November 2016

https://commonchemistry.cas.org/detail?cas_rn=115256-11-6

8 April 2021

1 reference

Dofetilide (English)

19 November 2016

1 reference

Dofetilide (English)

19 November 2016

Reaxys registry number

3572833

1 reference

dofetilide (English)

3 October 2016

mapping relation type

2 references

DOFETILIDE (English)

19 November 2016

International Chemical Identifier

InChI

InChI=1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3

1 reference

DOFETILIDE (English)

19 November 2016

2 references

inferred from InChIKey

splash10-0006-1610950000-368db21beef81a5319f4

1 reference

0 references

HSDB ID

7927

1 reference

Hazardous Substances Data Bank

28 October 2019

Dofetilide (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.166.441

27 December 2018

ECHA Substance Infocard ID

N-[4-(2-{[2-(4-methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide (English)

quotation

CAS no.: 115256-11-6 (English)

100.166.441

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.166.441

27 December 2018

N-[4-(2-{[2-(4-methanesulfonamidophenoxy)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide (English)

quotation

CAS no.: 115256-11-6 (English)

1 reference

Guide to Pharmacology Ligand ID

Dofetilide (English)

publication date

17 November 2015

2604

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2604

dofetilide (English)

19 November 2016

1 reference

Medical Subject Headings

14 March 2018

1 reference

dofetilide (English)

19 November 2016

1 reference

Human Metabolome Database ID

HMDB0014349

2 references

based on heuristic

inferred from InChIKey

2 references

dofetilide (English)

19 November 2016

MedlinePlus drug identifier

0 references

1 reference

dofetilide (English)

19 November 2016

0 references

1 reference

1 reference

dofetilide (English)

3 October 2016

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

dofetilide (English)

3 October 2016

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

UMLS CUI

C0114771

1 reference