The oncogenic lung cancer fusion kinase CD74-ROS activates a novel invasiveness pathway through E-Syt1 phosphorylation. (Q37122187)

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3 February 2020

title

The oncogenic lung cancer fusion kinase CD74-ROS activates a novel invasiveness pathway through E-Syt1 phosphorylation (English)

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3 February 2020

0 references

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neoplastic invasiveness

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5

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3 February 2020

author name string

Hyun Jung Jun

1

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3 February 2020

Hannah Johnson

2

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3 February 2020

Roderick T Bronson

3

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3 February 2020

Sebastien de Feraudy

4

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3 February 2020

Alain Charest

6

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3 February 2020

language of work or name

English

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publication date

1 June 2012

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3 February 2020

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3 February 2020

volume

72

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issue

15

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3 February 2020

page(s)

3764-3774

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RET, ROS1 and ALK fusions in lung cancer

3 February 2020

cites work

1 reference

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ROS1 rearrangements define a unique molecular class of lung cancers

14 September 2017

1 reference

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Lung cancer in 2010: One size does not fit all.

14 September 2017

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Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma

14 September 2017

1 reference

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Profiling Y561-dependent and -independent substrates of CSF-1R in epithelial cells

14 September 2017

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Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

14 September 2017

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Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases

14 September 2017

1 reference

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Screening for epidermal growth factor receptor mutations in lung cancer

14 September 2017

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Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma

14 September 2017

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An extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cells

14 September 2017

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14 September 2017

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The multifaceted roles of the receptor tyrosine kinase ROS in development and cancer

14 September 2017

1 reference

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Signaling networks assembled by oncogenic EGFR and c-Met

14 September 2017

1 reference

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Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

14 September 2017

1 reference

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E-Syts, a family of membranous Ca2 -sensor proteins with multiple C2 domains

14 September 2017

1 reference

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Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK.

14 September 2017

1 reference

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Membrane binding and subcellular targeting of C2 domains

14 September 2017

1 reference

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ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice

14 September 2017

1 reference

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Cre-lox-regulated conditional RNA interference from transgenes

14 September 2017

1 reference

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Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21)

14 September 2017

1 reference

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Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma

14 September 2017

1 reference

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Cloning and preliminary characterization of a 121 kDa protein with multiple predicted C2 domains

14 September 2017

1 reference

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Improved retroviral vectors for gene transfer and expression

14 September 2017

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Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions

14 September 2017

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Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants and kinetic studies with aminopyridine and triazolopyrazine inhibitors.

14 September 2017

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Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene.

27 June 2018

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ROS1 rearrangements in lung cancer: a new genomic subset of lung adenocarcinoma.

27 June 2018

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Phosphoproteomic characterization of PYK2 signaling pathways involved in osteogenesis

3 September 2018

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Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes

3 September 2018

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Design, synthesis, screening, and molecular modeling study of a new series of ROS1 receptor tyrosine kinase inhibitors.

3 September 2018

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Design, synthesis and biological evaluation of new potent and highly selective ROS1-tyrosine kinase inhibitor.

3 September 2018

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10.1158/0008-5472.CAN-11-3990

3 September 2018

Identifiers

DOI

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3 February 2020

1 reference

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3 February 2020

PubMed publication ID

22686350

1 reference

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