Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells. (Q37117826)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23918371 AND SRC:MED&resulttype=core&format=json

6 March 2020

title

Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells (English)

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6 March 2020

7

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6 March 2020

author name string

Lewis Zhichang Shi

1

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6 March 2020

Nishan S Kalupahana

2

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6 March 2020

Meghan E Turnis

3

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6 March 2020

Geoffrey Neale

4

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6 March 2020

Hanno Hock

5

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6 March 2020

Dario A A Vignali

6

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6 March 2020

language of work or name

English

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publication date

5 August 2013

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Proceedings of the National Academy of Sciences of the United States of America

6 March 2020

published in

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volume

110

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6 March 2020

issue

34

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6 March 2020

page(s)

E3198-205

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Selection of regulatory T cells in the thymus

6 March 2020

cites work

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14 September 2017

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T cells expressing the transcription factor PLZF regulate the development of memory-like CD8 T cells

14 September 2017

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Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

14 September 2017

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KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors

14 September 2017

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Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control.

14 September 2017

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The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.

14 September 2017

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Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103 inducible regulatory T cells.

14 September 2017

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Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces

14 September 2017

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Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

14 September 2017

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A two-step process for thymic regulatory T cell development.

14 September 2017

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BCL11B is required for positive selection and survival of double-positive thymocytes

14 September 2017

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

14 September 2017

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Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion

14 September 2017

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Kruppel-like factor 2 regulates thymocyte and T-cell migration

14 September 2017

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Zinc-finger transcription factor Gfi-1: versatile regulator of lymphocytes, neutrophils and hematopoietic stem cells

14 September 2017

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

14 September 2017

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Essential role for interleukin-2 for CD4( )CD25( ) T regulatory cell development during the neonatal period

14 September 2017

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Homeostatic maintenance of natural Foxp3( ) CD25( ) CD4( ) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

14 September 2017

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Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

14 September 2017

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Conversion of peripheral CD4 CD25- naive T cells to CD4 CD25 regulatory T cells by TGF-beta induction of transcription factor Foxp3

14 September 2017

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The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit T cell progenitors and CD4/CD8 lineage decision in the thymus

14 September 2017

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Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25 as well as CD25- regulatory T cells

14 September 2017

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

14 September 2017

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Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25( ) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

14 September 2017

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Inducible IL-2 production by dendritic cells revealed by global gene expression analysis.

14 September 2017

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Induction of tumor immunity by removing CD25 CD4 T cells: a common basis between tumor immunity and autoimmunity

14 September 2017

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Gfi1 negatively regulates T(h)17 differentiation by inhibiting RORgammat activity

14 September 2017

1 reference

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SAP Protein-Dependent Natural Killer T-like Cells Regulate the Development of CD8 T Cells with Innate Lymphocyte Characteristics

14 September 2017

1 reference

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A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752244

Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease.

27 June 2018

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Differential impact of the transcriptional repressor Gfi1 on mature CD4 and CD8 T lymphocyte function

3 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752244

Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells

3 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752244

Gfi1:green fluorescent protein knock-in mutant reveals differential expression and autoregulation of the growth factor independence 1 (Gfi1) gene during lymphocyte development

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752244

Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752244

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

3 September 2018

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Transgenic mice with hematopoietic and lymphoid specific expression of Cre

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12 December 2020

Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses

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12 December 2020

A critical function for TGF-beta signaling in the development of natural CD4 CD25 Foxp3 regulatory T cells

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12 December 2020

Stat3 and Gfi-1 Transcription Factors Control Th17 Cell Immunosuppressive Activity via the Regulation of Ectonucleotidase Expression

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12 December 2020

Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1

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Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1300950110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23918371 AND SRC:MED&resulttype=core&format=json

6 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23918371 AND SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

23918371

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23918371 AND SRC:MED&resulttype=core&format=json