Systemic microdystrophin gene delivery improves skeletal muscle structure and function in old dystrophic mdx mice. (Q37116446)

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4 January 2020

title

Systemic microdystrophin gene delivery improves skeletal muscle structure and function in old dystrophic mdx mice (English)

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4 January 2020

1

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4 January 2020

Jeffrey S Chamberlain

series ordinal

4

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4 January 2020

author name string

Michael J Blankinship

series ordinal

2

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4 January 2020

James M Allen

series ordinal

3

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4 January 2020

publication date

4 March 2008

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4 January 2020

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4 January 2020

volume

16

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4 January 2020

issue

4

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4 January 2020

page(s)

657-664

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Viral-mediated gene therapy for the muscular dystrophies: successes, limitations and recent advances

4 January 2020

cites work

1 reference

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rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.

14 September 2017

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Body-wide gene therapy of Duchenne muscular dystrophy in the mdx mouse model.

14 September 2017

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Differential proteome analysis of aging in rat skeletal muscle

14 September 2017

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Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury.

14 September 2017

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Rescue of dystrophic muscle through U7 snRNA-mediated exon skipping

14 September 2017

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Systemic delivery of genes to striated muscles using adeno-associated viral vectors.

14 September 2017

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Human circulating AC133( ) stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle

14 September 2017

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Quantitative magnetic resonance (QMR) method for bone and whole-body-composition analysis

14 September 2017

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Improved contractile function of the mdx dystrophic mouse diaphragm muscle after insulin-like growth factor-I administration

14 September 2017

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Functional correction of adult mdx mouse muscle using gutted adenoviral vectors expressing full-length dystrophin.

14 September 2017

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Dystrophin protects the sarcolemma from stresses developed during muscle contraction

14 September 2017

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A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin.

14 September 2017

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The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein

14 September 2017

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Dystrophin-deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma

14 September 2017

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Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

3 September 2018

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Identification of a molecular signature of sarcopenia

3 September 2018

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Efficient transduction of skeletal muscle using vectors based on adeno-associated virus serotype 6.

3 September 2018

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Sustained improvement of muscle function one year after full-length dystrophin gene transfer into mdx mice by a gutted helper-dependent adenoviral vector

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650831

Evaluation of a quantitative magnetic resonance method for mouse whole body composition analysis

3 September 2018

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Transcriptional profiling identifies extensive downregulation of extracellular matrix gene expression in sarcopenic rat soleus muscle.

3 September 2018

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Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse

3 September 2018

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Adeno-associated virus vector-mediated minidystrophin gene therapy improves dystrophic muscle contractile function in mdx mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650831

Adeno-associated virus vector gene transfer and sarcolemmal expression of a 144 kDa micro-dystrophin effectively restores the dystrophin-associated protein complex and inhibits myofibre degeneration in nude/mdx mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650831

Modular flexibility of dystrophin: implications for gene therapy of Duchenne muscular dystrophy

3 September 2018

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Improved adeno-associated virus vector production with transfection of a single helper adenovirus gene, E4orf6.

3 September 2018

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The homologue of the Duchenne locus is defective in X-linked muscular dystrophy of dogs

3 September 2018

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12 December 2020

The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy

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12 December 2020

Differential expression of muscular dystrophy in diaphragm versus hindlimb muscles of mdx mice

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12 December 2020

Site-dependent pathological differences in smooth muscles and skeletal muscles of the adult mdx mouse

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12 December 2020

Phenotype of dystrophinopathy in old MDX mice

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12 December 2020

mdx mice show progressive weakness and muscle deterioration with age

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12 December 2020

Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice

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12 December 2020

Major clinical and histopathological characteristics of canine X-linked muscular dystrophy in Japan, CXMDJ

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12 December 2020

Branched fibers in dystrophic mdx muscle are associated with a loss of force following lengthening contractions

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12 December 2020

Force and power output of fast and slow skeletal muscles from mdx mice 6-28 months old

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Dissecting the signaling and mechanical functions of the dystrophin-glycoprotein complex

1 reference

Crossref

https://api.crossref.org/works/10.1038/MT.2008.28

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/MT.2008.28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18334986 AND SRC:MED&resulttype=core&format=json

release_anixaviqnngqnlpfmm3wyzdn5y

4 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/anixaviqnngqnlpfmm3wyzdn5y

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18334986 AND SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

18334986

1 reference