Metronomic dosing of BH3 mimetic small molecule yields robust antiangiogenic and antitumor effects (Q37109324)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158856 AND SRC:MED&resulttype=core&format=json

18 January 2020

title

Metronomic dosing of BH3 mimetic small molecule yields robust antiangiogenic and antitumor effects (English)

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18 January 2020

main subject

angiogenesis inhibitor

1 reference

2

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18 January 2020

Shaomeng Wang

9

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18 January 2020

author name string

Atsushi Imai

1

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18 January 2020

Fernanda Visioli

3

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18 January 2020

Zhihong Dong

4

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18 January 2020

Zhaocheng Zhang

5

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18 January 2020

Sudha Krishnamurthy

6

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18 January 2020

Emily Light

7

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18 January 2020

Frank Worden

8

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18 January 2020

Jacques E Nör

10

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18 January 2020

language of work or name

English

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publication date

8 December 2011

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18 January 2020

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18 January 2020

volume

72

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18 January 2020

issue

3

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18 January 2020

page(s)

716-725

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Metronomic small molecule inhibitor of Bcl-2 (TW-37) is antiangiogenic and potentiates the antitumor effect of ionizing radiation

18 January 2020

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Expanding circle of inhibition: small-molecule inhibitors of Bcl-2 as anticancer cell and antiangiogenic agents

14 September 2017

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(-)-gossypol inhibits growth and promotes apoptosis of human head and neck squamous cell carcinoma in vivo

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice

14 September 2017

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Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer

14 September 2017

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Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression

14 September 2017

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14 September 2017

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Overcoming drug resistance in hormone- and drug-refractory prostate cancer cell line, PC-3 by docetaxel and gossypol combination.

14 September 2017

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Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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12 December 2020

The prognostic value of spontaneous apoptosis, Bax, Bcl-2, and p53 in oral squamous cell carcinoma of the tongue

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12 December 2020

Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma

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12 December 2020

A novel metronomic chemotherapy regimen of weekly platinum and daily oral etoposide in high-risk non-small cell lung cancer patients

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12 December 2020

Antiangiogenic effect of TW37, a small-molecule inhibitor of Bcl-2

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12 December 2020

A phase II trial of continuous low-dose oral cyclophosphamide and celecoxib in patients with renal cell carcinoma

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12 December 2020

Unidirectional crosstalk between Bcl-xL and Bcl-2 enhances the angiogenic phenotype of endothelial cells

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12 December 2020

Bcl-2 Orchestrates a Cross-talk between Endothelial and Tumor Cells that Promotes Tumor Growth

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12 December 2020

10.1158/0008-5472.CAN-10-2873

Identifiers

DOI

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release_lkfmbm7npngwxj7jkyktj76gom

18 January 2020

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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18 January 2020

PubMed publication ID

22158856

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