Severe neurological phenotypes of Q129 DRPLA transgenic mice serendipitously created by en masse expansion of CAG repeats in Q76 DRPLA mice. (Q37090117)

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17 January 2020

title

Severe neurological phenotypes of Q129 DRPLA transgenic mice serendipitously created by en masse expansion of CAG repeats in Q76 DRPLA mice (English)

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17 January 2020

10

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Osamu Onodera

13

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17 January 2020

14

Christopher A Ross

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17 January 2020

author name string

Toshiya Sato

1

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17 January 2020

Masami Miura

2

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17 January 2020

Mitsunori Yamada

3

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17 January 2020

Takayuki Yoshida

4

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17 January 2020

Jonathan D Wood

5

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17 January 2020

Ikuru Yazawa

6

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17 January 2020

Masao Masuda

7

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17 January 2020

Takeo Suzuki

8

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17 January 2020

Ryong-Moon Shin

9

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17 January 2020

Fu-Chin Liu

11

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17 January 2020

Takayoshi Shimohata

12

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17 January 2020

Motoya Katsuki

15

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17 January 2020

Hitoshi Takahashi

16

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17 January 2020

Masanobu Kano

17

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17 January 2020

Toshihiko Aosaki

18

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17 January 2020

Shoji Tsuji

19

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17 January 2020

publication date

27 November 2008

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17 January 2020

published in

Human Molecular Genetics

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volume

18

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17 January 2020

issue

4

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17 January 2020

page(s)

723-736

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Neuronal atrophy and synaptic alteration in a mouse model of dentatorubral-pallidoluysian atrophy

17 January 2020

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Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA.

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Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients.

29 September 2017

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Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins

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3 September 2018

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Atrophy of the cerebellum and brainstem in dentatorubral pallidoluysian atrophy. Influence of CAG repeat size on MRI findings

3 September 2018

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Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.

3 September 2018

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Molecular cloning of murine homologue dentatorubral-pallidoluysian atrophy (DRPLA) cDNA: strong conservation of a polymorphic CAG repeat in the murine gene

3 September 2018

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3 September 2018

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De novo expansion of a (CAG)n repeat in sporadic Huntington's disease

3 September 2018

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Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19039037

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hereditary dentatorubral-pallidoluysian atrophy: Clinical and pathologic variants in a family

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19039037

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dentatorubral-pallidoluysian atrophy: clinical features are closely related to unstable expansions of trinucleotide (CAG) repeat

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19039037

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDN403

1 reference

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17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19039037 AND SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

19039037

1 reference