Long-range regulation of alpha-globin gene expression (Q37087582)

18 August 2017

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title

Long-range regulation of alpha-globin gene expression (English)

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18 August 2017

Douglas R Higgs

1

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author name string

Douglas Vernimmen

series ordinal

2

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18 August 2017

Bill Wood

series ordinal

3

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18 August 2017

publication date

1 January 2008

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18 August 2017

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18 August 2017

volume

61

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18 August 2017

page(s)

143-173

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The NF-E2 transcription factor

18 August 2017

cites work

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Deletion of the mouse alpha-globin regulatory element (HS -26) has an unexpectedly mild phenotype

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Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2.

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The complex language of chromatin regulation during transcription

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Krüppel-like factors: three fingers in many pies

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Coregulated human globin genes are frequently in spatial proximity when active

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Bystander gene activation by a locus control region

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Transcriptional regulation of erythropoiesis: an affair involving multiple partners

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Core promoter elements and TAFs contribute to the diversity of transcriptional activation in vertebrates

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A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter

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Tissue-specific histone modification and transcription factor binding in alpha globin gene expression.

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Human α-globin gene expression following chromosomal dependent gene transfer into mouse erythroleukemia cells

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Capturing chromosome conformation

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Non-erythroid genes inserted on either side of human HS-40 impair the activation of its natural alpha -globin gene targets without being themselves preferentially activated

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Controlling the double helix

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The relationship between chromosome structure and function at a human telomeric region

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Gene expression in proliferating human erythroid cells

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7 January 2021

Dynamics of enhancer-promoter communication during differentiation-induced gene activation

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ATP-dependent chromatin remodeling activities.

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A major positive regulatory region located far upstream of the human alpha-globin gene locus

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Annotation of cis-regulatory elements by identification, subclassification, and functional assessment of multispecies conserved sequences

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Finishing the euchromatic sequence of the human genome

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Characterization of the major regulatory element upstream of the human alpha-globin gene cluster

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7 January 2021

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

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7 January 2021

Characterization and comparison of the human and mouse Dist1/alpha-globin complex reveals a tightly packed multiple gene cluster containing differentially expressed transcription units.

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7 January 2021

Long-range control of gene expression: emerging mechanisms and disruption in disease

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7 January 2021

Recruitment of transcription complexes to the beta-globin locus control region and transcription of hypersensitive site 3 prior to erythroid differentiation of murine embryonic stem cells

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7 January 2021

Locus control regions

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7 January 2021

The molecular biology of the CCAAT-binding factor NF-Y

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7 January 2021

Transcriptional Regulatory Elements in the Human Genome

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Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

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7 January 2021

DNA-binding specificity of GATA family transcription factors

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7 January 2021

Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

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7 January 2021

The role of LMO2 in development and in T cell leukemia after chromosomal translocation or retroviral insertion

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7 January 2021

Diversification of haematopoietic stem cells to specific lineages.

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7 January 2021

Active genes dynamically colocalize to shared sites of ongoing transcription

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7 January 2021

The beta-globin nuclear compartment in development and erythroid differentiation

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7 January 2021

Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity

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7 January 2021

A newly identified deletion of 970 bp at the alpha-globin locus that removes the promoter region of the alpha1 gene

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7 January 2021

Organization of the alpha-globin promoter and possible role of nuclear factor I in an alpha-globin-inducible and a noninducible cell line.

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7 January 2021

Transcriptional activation of human adult alpha-globin genes by hypersensitive site-40 enhancer: function of nuclear factor-binding motifs occupied in erythroid cells

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7 January 2021

Long-range intrachromosomal interactions in the T helper type 2 cytokine locus

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7 January 2021

Interchromosomal associations between alternatively expressed loci

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7 January 2021

CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus

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7 January 2021

Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

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7 January 2021

In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction

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7 January 2021

The Sp-family of transcription factors

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7 January 2021

Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage.

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7 January 2021

The role of enhancers as centres for general transcription factor recruitment.

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7 January 2021

Genomic rearrangement of the alpha-globin gene complex during mammalian evolution

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7 January 2021

Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice.

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7 January 2021

Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1.

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7 January 2021

Impaired hematopoiesis in mice lacking the transcription factor Sp3

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7 January 2021

Long-range chromosomal interactions regulate the timing of the transition between poised and active gene expression

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https://api.crossref.org/works/10.1016/S0065-2660(07)50005-3

7 January 2021

De novo deletion within the telomeric region flanking the human alpha globin locus as a cause of alpha thalassaemia

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https://api.crossref.org/works/10.1016/S0065-2660(07)50005-3

7 January 2021

A novel deletion causing alpha thalassemia clarifies the importance of the major human alpha globin regulatory element

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https://api.crossref.org/works/10.1016/S0065-2660(07)50005-3

7 January 2021

The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation

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https://api.crossref.org/works/10.1016/S0065-2660(07)50005-3

7 January 2021

Cis-acting sequences regulating expression of the human alpha-globin cluster lie within constitutively open chromatin

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https://api.crossref.org/works/10.1016/S0065-2660(07)50005-3

7 January 2021

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

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7 January 2021

Manipulating the mouse genome to engineer precise functional syntenic replacements with human sequence

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https://api.crossref.org/works/10.1016/S0065-2660(07)50005-3

7 January 2021

Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking

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https://api.crossref.org/works/10.1016/S0065-2660(07)50005-3

7 January 2021

Global regulation of erythroid gene expression by transcription factor GATA-1

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https://api.crossref.org/works/10.1016/S0065-2660(07)50005-3

7 January 2021

Transcription complex stability and chromatin dynamics in vivo

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https://api.crossref.org/works/10.1016/S0065-2660(07)50005-3

7 January 2021

Multiple arrangements of the human embryonic zeta globin genes

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https://api.crossref.org/works/10.1016/S0065-2660(07)50005-3

7 January 2021

Chromatin structure and developmental expression of the human alpha-globin cluster

1 reference

https://api.crossref.org/works/10.1016/S0065-2660(07)50005-3

7 January 2021

Functional roles of in vivo footprinted DNA motifs within an alpha-globin enhancer. Erythroid lineage and developmental stage specificities

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7 January 2021

Genome-wide high-resolution mapping and functional analysis of DNA methylation in arabidopsis

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7 January 2021

10.1016/S0065-2660(07)00005-3

Identifiers

DOI

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18 August 2017

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