Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer (Q37082792)

18 August 2017

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title

Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer (English)

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18 August 2017

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Darren D Browning

1

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18 August 2017

language of work or name

English

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publication date

1 March 2008

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Expert Opinion on Therapeutic Targets

18 August 2017

published in

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18 August 2017

volume

12

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18 August 2017

issue

3

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18 August 2017

page(s)

367-376

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Adjuvant therapy of colon cancer: current status and future directions.

18 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Diarrhea or colorectal cancer: can bacterial toxins serve as a treatment for colon cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Bacterial enterotoxins are associated with resistance to colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Cross-talk between enteric pathogens and the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Proliferative signaling by store-operated calcium channels opposes colon cancer cell cytostasis induced by bacterial enterotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Interruption of homologous desensitization in cyclic guanosine 3',5'-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Tracking functions of cGMP-dependent protein kinases (cGK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Cyclic GMP-dependent protein kinases: understanding in vivo functions by gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

An anti-tumor role for cGMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Characterization of the human gene encoding the type I alpha and type I beta cGMP-dependent protein kinase (PRKG1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Molecular cloning, cDNA structure, and chromosomal localization of the human type II cGMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Mechanisms of guanylin action via cyclic GMP in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

cGMP stimulation of cystic fibrosis transmembrane conductance regulator Cl- channels co-expressed with cGMP-dependent protein kinase type II but not type Ibeta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Effect of cell passage and density on protein kinase G expression and activation in vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Profiling of protein kinases in the neoplastic transformation of human ovarian surface epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Natriuretic peptide signalling: molecular and cellular pathways to growth regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Cyclic GMP-dependent protein kinase in nitric oxide signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Role of cyclic GMP in gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Regulation of vascular smooth muscle cell phenotype by cyclic GMP and cyclic GMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Evidence for the involvement of cGMP and protein kinase G in nitric oxide-induced apoptosis in the pancreatic B-cell line, HIT-T15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Inhibition of cGMP-dependent protein kinases potently decreases neutrophil spontaneous apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Exisulind and CP248 induce growth inhibition and apoptosis in human esophageal adenocarcinoma and squamous carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Exisulind in the treatment of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Effects of sulindac and its metabolites on growth and apoptosis in human mammary epithelial and breast carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Exisulind, a selective apoptotic antineoplastic drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Protein kinase G activates the JNK1 pathway via phosphorylation of MEKK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Nitric oxide activation of p38 mitogen-activated protein kinase in 293T fibroblasts requires cGMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Activation of p38 mitogen-activated protein kinase by lipopolysaccharide in human neutrophils requires nitric oxide-dependent cGMP accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Molecular mechanisms of "detachment-induced apoptosis--Anoikis".

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Apoptosis, anoikis and their relevance to the pathobiology of colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

A role for cyclic-GMP dependent protein kinase in anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

21 January 2018

Integrins and anoikis

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Anchorage dependence, integrins, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Regulation of vasodilator-stimulated phosphoprotein phosphorylation and interaction with Abl by protein kinase A and cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

The E-cadherin-catenin complex in tumour metastasis: structure, function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

The cadherin-catenin adhesion system in signaling and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Directed actin polymerization is the driving force for epithelial cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Functional analysis of type 1alpha cGMP-dependent protein kinase using green fluorescent fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Role of protein kinase G in barrier-protective effects of cGMP in human pulmonary artery endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Cadherins and catenins: role in signal transduction and tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

The subcellular destinations of APC proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Turn-off, drop-out: functional state switching of cadherins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Convergence of Wnt, beta-catenin, and cadherin pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Decisions, decisions: beta-catenin chooses between adhesion and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Beta-catenin N- and C-terminal tails modulate the coordinated binding of adherens junction proteins to beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Regulation of beta-catenin structure and activity by tyrosine phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Endogenous stimulators and inhibitors of angiogenesis in gastrointestinal cancers: basic science to clinical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

You Wnt some, you lose some: oncogenes in the Wnt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Non-traditional roles for the Adenomatous Polyposis Coli (APC) tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Hereditary colorectal cancer syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Down-regulation of beta catenin inhibits the growth of esophageal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Uroguanylin and guanylin peptides: pharmacology and experimental therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

The Wnt/beta-catenin signaling pathway as a target in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Wnt/beta-catenin signaling pathway as a novel cancer drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Atrial natriuretic peptide attenuates hypoxia induced chemoresistance in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Chemosensitization of cancer in vitro and in vivo by nitric oxide signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Nitric-oxide-donating NSAIDs as agents for cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Nitric oxide-donating aspirin inhibits β-catenin/T cell factor (TCF) signaling in SW480 colon cancer cells by disrupting the nuclear β-catenin–TCF association

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Phosphodiesterase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

Ligand-based histochemical localization and capture of cells expressing heat-stable enterotoxin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/14728222.12.3.367

10.1517/14728222.12.3.367

21 January 2018

Identifiers

DOI

1 reference

18 August 2017

1 reference