MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy (Q37061259)

18 August 2017

MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy (English)

1 reference

18 August 2017

Protein kinase C, alpha

1 reference

Phospholipase C, beta 1

1 reference

Cysteine and glycine-rich protein 3

1 reference

Ankyrin repeat domain 1 (cardiac muscle)

1 reference

Marie-Louise Bang

9

0 references

Stephan Lange

object named as

Stephan Lange

1

0 references

Elisabeth Ehler

object named as

Elisabeth Ehler

14

0 references

author name string

Katja Gehmlich

2

1 reference

18 August 2017

Alexander S Lun

3

1 reference

18 August 2017

Jordan Blondelle

4

1 reference

18 August 2017

Charlotte Hooper

5

1 reference

18 August 2017

Nancy D Dalton

6

1 reference

18 August 2017

Erika A Alvarez

7

1 reference

18 August 2017

Xiaoyu Zhang

8

1 reference

18 August 2017

Yama A Abassi

10

1 reference

18 August 2017

Cristobal G Dos Remedios

11

1 reference

18 August 2017

Kirk L Peterson

12

1 reference

18 August 2017

Ju Chen

13

1 reference

18 August 2017

language of work or name

English

0 references

publication date

29 June 2016

1 reference

18 August 2017

Nature Communications

1 reference

18 August 2017

7

1 reference

18 August 2017

12120

1 reference

Creative Commons Attribution 4.0 International

18 August 2017

start time

29 June 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4931343/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Induction of Ankrd1 in Dilated Cardiomyopathy Correlates with the Heart Failure Progression

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Targeted inhibition of ANKRD1 disrupts sarcomeric ERK-GATA4 signal transduction and abrogates phenylephrine-induced cardiomyocyte hypertrophy

29 September 2017

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Profiling of skeletal muscle Ankrd2 protein in human cardiac tissue and neonatal rat cardiomyocytes

29 September 2017

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Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodeling

29 September 2017

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Probing muscle ankyrin-repeat protein (MARP) structure and function

29 September 2017

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Human muscle LIM protein dimerizes along the actin cytoskeleton and cross-links actin filaments

29 September 2017

1 reference

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The muscle ankyrin repeat proteins CARP, Ankrd2, and DARP are not essential for normal cardiac development and function at basal conditions and in response to pressure overload

29 September 2017

1 reference

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Protein phosphatase 2A is regulated by protein kinase Cα (PKCα)-dependent phosphorylation of its targeting subunit B56α at Ser41.

29 September 2017

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Deletion of the β2-adrenergic receptor prevents the development of cardiomyopathy in mice

29 September 2017

1 reference

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Impact of ANKRD1 mutations associated with hypertrophic cardiomyopathy on contraction parameters of engineered heart tissue.

29 September 2017

1 reference

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Signaling effectors underlying pathologic growth and remodeling of the heart

29 September 2017

1 reference

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Cardiac ankyrin repeat protein attenuates cardiac hypertrophy by inhibition of ERK1/2 and TGF-β signaling pathways

29 September 2017

1 reference

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Structure-based prediction of protein–protein interactions on a genome-wide scale

29 September 2017

1 reference

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The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development

29 September 2017

1 reference

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Muscle ankyrin repeat proteins: their role in striated muscle function in health and disease

29 September 2017

1 reference

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Functional cardiotoxicity profiling and screening using the xCELLigence RTCA Cardio System

29 September 2017

1 reference

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Multi-tasking role of the mechanosensing protein Ankrd2 in the signaling network of striated muscle

29 September 2017

1 reference

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EH-myomesin splice isoform is a novel marker for dilated cardiomyopathy

29 September 2017

1 reference

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Protein kinase C: poised to signal

29 September 2017

1 reference

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Calcineurin protects the heart in a murine model of dilated cardiomyopathy

29 September 2017

1 reference

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PKC phosphorylation of titin's PEVK element: a novel and conserved pathway for modulating myocardial stiffness

29 September 2017

1 reference

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Cardiac ankyrin repeat protein gene (ANKRD1) mutations in hypertrophic cardiomyopathy

29 September 2017

1 reference

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ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Myocyte remodeling in response to hypertrophic stimuli requires nucleocytoplasmic shuttling of muscle LIM protein

29 September 2017

1 reference

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Protein kinase C in heart failure: a therapeutic target?

29 September 2017

1 reference

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Beta-adrenergic stimulation and myocardial function in the failing heart

29 September 2017

1 reference

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An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice

29 September 2017

1 reference

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The enigmatic role of the ankyrin repeat domain 1 gene in heart development and disease.

29 September 2017

1 reference

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Beyond the sarcomere: CSRP3 mutations cause hypertrophic cardiomyopathy

29 September 2017

1 reference

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Cardiac dysfunction and heart failure are associated with abnormalities in the subcellular distribution and amounts of oligomeric muscle LIM protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure

29 September 2017

1 reference

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Phosphate-binding tag, a new tool to visualize phosphorylated proteins

29 September 2017

1 reference

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Protein kinase cascades in the regulation of cardiac hypertrophy

29 September 2017

1 reference

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PKC-alpha regulates cardiac contractility and propensity toward heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Protein Kinase Cα Negatively Regulates Systolic and Diastolic Function in Pathological Hypertrophy

29 September 2017

1 reference

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The Muscle Ankyrin Repeat Proteins: CARP, ankrd2/Arpp and DARP as a Family of Titin Filament-based Stress Response Molecules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Cardiac ankyrin repeat protein, a negative regulator of cardiac gene expression, is augmented in human heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Alterations at the intercalated disk associated with the absence of muscle LIM protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Decreased expression of the cardiac LIM domain protein MLP in chronic human heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

The muscle regulatory and structural protein MLP is a cytoskeletal binding partner of betaI-spectrin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

A novel cardiac-restricted target for doxorubicin. CARP, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Muscle LIM Protein Promotes Myogenesis by Enhancing the Activity of MyoD

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Transgenic Gαq overexpression induces cardiac contractile failure in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Specificity of single LIM motifs in targeting and LIM/LIM interactions in situ

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Muscle LIM protein, a novel essential regulator of myogenesis, promotes myogenic differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

The LIM domain is a modular protein-binding interface

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Isolation and culture of neonatal mouse cardiomyocytes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Overexpression of beta2-adrenergic receptors cAMP-dependent protein kinase phosphorylates and modulates slow delayed rectifier potassium channels expressed in murine heart: evidence for receptor/channel co-localization

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Adaptations of cytoarchitecture in human dilated cardiomyopathy

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931343

Identification and characterization of G protein-regulated phospholipase C in human myocardium

4 September 2018

1 reference

12 December 2020

Increased protein kinase C activity and expression of Ca2 -sensitive isoforms in the failing human heart

1 reference

12 December 2020

Augmented protein kinase C-alpha-induced myofilament protein phosphorylation contributes to myofilament dysfunction in experimental congestive heart failure

1 reference

12 December 2020

PKC translocation without changes in Galphaq and PLC-beta protein abundance in cardiac hypertrophy and failure

1 reference

12 December 2020

Muscle LIM protein: expressed in slow muscle and induced in fast muscle by enhanced contractile activity

1 reference

12 December 2020

Cardiac remodeling is not modulated by overexpression of muscle LIM protein (MLP)

1 reference

12 December 2020

Protein kinase C in the human heart: differential regulation of the isoforms in aortic stenosis or dilated cardiomyopathy

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS12120

1 reference

Dimensions Publication ID

18 August 2017

0 references

0 references

1 reference

18 August 2017

PubMed publication ID

27353086

1 reference