Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer (Q37046332)

17 August 2017

Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer (English)

1 reference

17 August 2017

Devika Agarwal

5

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Mohammed A Aleskandarany

Mohammed A Aleskandarany

7

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Srinivasan Madhusudan

Srinivasan Madhusudan

10

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Ian Ellis

Ian O Ellis

8

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Yves Pommier

9

Yves Pommier

1 reference

17 August 2017

Raghavendra A Shamanna

1

1 reference

17 August 2017

Huiming Lu

2

1 reference

17 August 2017

Deborah L Croteau

3

1 reference

17 August 2017

Arvind Arora

4

1 reference

17 August 2017

Graham Ball

6

1 reference

17 August 2017

Vilhelm A Bohr

11

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17 August 2017

language of work or name

English

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publication date

3 March 2016

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17 August 2017

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17 August 2017

7

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17 August 2017

12

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17 August 2017

13269-13284

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describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4924640/fullTextXML

inferred from PubMed Central ID database lookup

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Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress

29 September 2017

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The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage

29 September 2017

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Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity

29 September 2017

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Recql5 plays an important role in DNA replication and cell survival after camptothecin treatment

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin

29 September 2017

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29 September 2017

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Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells.

29 September 2017

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29 September 2017

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SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage

29 September 2017

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Nucleolar localization of the Werner syndrome protein in human cells

29 September 2017

1 reference

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29 September 2017

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Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer.

29 September 2017

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4 September 2018

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A polymorphism in Werner syndrome gene is associated with breast cancer susceptibility in Chinese women

4 September 2018

1 reference

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Role for the Werner syndrome protein in the promotion of tumor cell growth.

4 September 2018

1 reference

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Reporting recommendations for tumor marker prognostic studies (REMARK).

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924640

Werner protein stimulates topoisomerase I DNA relaxation activity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924640

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

4 September 2018

1 reference

12 December 2020

Genetic variation in the premature aging gene WRN: a case-control study on breast cancer susceptibility

1 reference

12 December 2020

Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin

1 reference

12 December 2020

Camptothecin induction of a time- and concentration-dependent decrease of topoisomerase I and its implication in camptothecin activity

1 reference

12 December 2020

Identifiers

DOI

10.18632/ONCOTARGET.7906

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

26959889

1 reference