APRIL stimulates NF-κB-mediated HoxC4 induction for AID expression in mouse B cells. (Q37045143)

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18 February 2020

title

APRIL stimulates NF-κB-mediated HoxC4 induction for AID expression in mouse B cells (English)

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18 February 2020

0 references

1

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18 February 2020

author name string

Pyeung-Hyeun Kim

2

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18 February 2020

Kyu-Seon Lee

3

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18 February 2020

Sang-Hoon Lee

4

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18 February 2020

Goo-Young Seo

5

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Yung-Choon Yoo

6

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Junglim Lee

7

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Paolo Casali

8

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publication date

21 November 2012

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18 February 2020

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volume

61

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issue

2

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page(s)

608-613

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Immunoglobulin class-switch DNA recombination: induction, targeting and beyond

18 February 2020

cites work

1 reference

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BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway

29 September 2017

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Selective APRIL blockade delays systemic lupus erythematosus in mouse

29 September 2017

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AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4

29 September 2017

1 reference

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Macrophage-derived BAFF induces AID expression through the p38MAPK/CREB and JNK/AP-1 pathways

29 September 2017

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Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutation

29 September 2017

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Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity

29 September 2017

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HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation

29 September 2017

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Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination.

29 September 2017

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Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination

29 September 2017

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IL-4-induced AID expression and its relevance to IgA class switch recombination

29 September 2017

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B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling

29 September 2017

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BAFF, APRIL and their receptors: structure, function and signaling

29 September 2017

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Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein

29 September 2017

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Identification of a ubiquitously active promoter of the murine activation-induced cytidine deaminase (AICDA) gene

29 September 2017

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The role of APRIL and BAFF in lymphocyte activation

29 September 2017

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Identification of proteoglycans as the APRIL-specific binding partners.

29 September 2017

1 reference

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Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation.

29 September 2017

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TACI and BAFF-R mediate isotype switching in B cells

29 September 2017

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The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination

29 September 2017

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Impaired IgA class switching in APRIL-deficient mice

29 September 2017

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The balance between Pax5 and Id2 activities is the key to AID gene expression

29 September 2017

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Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements

29 September 2017

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DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

29 September 2017

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Smad3 and Smad4 mediate transforming growth factor-beta1-induced IgA expression in murine B lymphocytes.

29 September 2017

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29 September 2017

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TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Interleukin 5 and interleukin 4 produced by Peyer's patch T cells selectively enhance immunoglobulin A expression.

27 June 2018

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E-proteins directly regulate expression of activation-induced deaminase in mature B cells

27 June 2018

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Transient activation of NF-kappaB through a TAK1/IKK kinase pathway by TGF-beta1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor formation

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23178148

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CYTO.2012.10.018

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release_bgtmblke6va7pj2d7ekk5aduwq

18 February 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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18 February 2020

PubMed publication ID

23178148

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