Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia (Q37040899)

17 August 2017

Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia (English)

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17 August 2017

5

Dafna Bar-Sagi

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17 August 2017

Yuliya Pylayeva-Gupta

1

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17 August 2017

Kyoung Eun Lee

2

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17 August 2017

Cristina H Hajdu

3

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17 August 2017

George Miller

4

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17 August 2017

1 June 2012

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17 August 2017

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17 August 2017

21

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17 August 2017

6

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17 August 2017

836-847

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describes a project that uses

17 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3721510/fullTextXML

inferred from PubMed Central ID database lookup

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Murine pancreatic adenocarcinoma dampens SHIP-1 expression and alters MDSC homeostasis and function

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RAS oncogenes: weaving a tumorigenic web

29 September 2017

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Molecular Signatures of Pancreatic Cancer

29 September 2017

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Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication

29 September 2017

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Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.

29 September 2017

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Endogenous T Cell Responses to Antigens Expressed in Lung Adenocarcinomas Delay Malignant Tumor Progression

29 September 2017

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The complexity of pancreatic ductal cancers and multidimensional strategies for therapeutic targeting

29 September 2017

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Oncogenic KRas Suppresses Inflammation-Associated Senescence of Pancreatic Ductal Cells

29 September 2017

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Immunity, Inflammation, and Cancer

29 September 2017

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Lymphocytes in cancer development: polarization towards pro-tumor immunity

29 September 2017

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Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF.

29 September 2017

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GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells

29 September 2017

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Myeloid-derived suppressor cells: linking inflammation and cancer

29 September 2017

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Myeloid-derived suppressor cells as regulators of the immune system

29 September 2017

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

29 September 2017

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Immunosurveillance of pancreatic adenocarcinoma: insights from genetically engineered mouse models of cancer.

29 September 2017

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Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice.

29 September 2017

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A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors

29 September 2017

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Colony-stimulating factors in inflammation and autoimmunity.

29 September 2017

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Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells.

29 September 2017

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Oncogenic ras-induced expression of cytokines: a new target of anti-cancer therapeutics

29 September 2017

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Ectopic lymphoid tissues and local immunity

29 September 2017

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29 September 2017

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Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression

29 September 2017

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Pancreatic cancer microenvironment

29 September 2017

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Stromal biology of pancreatic cancer

29 September 2017

1 reference

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Naturally occurring T-cell response against mutated p21 ras oncoprotein in pancreatic cancer

29 September 2017

1 reference

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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

29 September 2017

1 reference

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Regulation of myeloid development and function by colony stimulating factors.

29 September 2017

1 reference

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Stimulation of angiogenesis by Ras proteins

29 September 2017

1 reference

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Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

29 September 2017

1 reference

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The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

29 September 2017

1 reference

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

29 September 2017

1 reference

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Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8 T cell responses by dysregulating antigen-presenting cell maturation.

29 September 2017

1 reference

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Modulation of the immune response and tumor growth by activated Ras.

29 September 2017

1 reference

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Mutated Ras peptides as vaccines in immunotherapy of cancer

29 September 2017

1 reference

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CD8 T cells from a patient with colon carcinoma, specific for a mutant p21-Ras-derived peptide (Gly13-->Asp), are cytotoxic towards a carcinoma cell line harbouring the same mutation

29 September 2017

1 reference

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Transcriptional regulation of mouse granulocyte-macrophage colony-stimulating factor/IL-3 locus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721510

A ras-mutated peptide targeted by CTL infiltrating a human melanoma lesion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721510

Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721510

Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721510

T cell epitopes encompassing the mutational hot spot position 61 of p21 ras. Promiscuity in ras peptide binding to HLA.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721510

CD4 T-cell immunity to mutated ras protein in pancreatic and colon cancer patients

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721510

Hematopoietic cytokines in the sera of patients with pancreatic cancer

20 October 2018

1 reference

12 December 2020

Pancreatic duct epithelial cell isolation and cultivation in two-dimensional and three-dimensional culture systems

1 reference

12 December 2020

Dynamics of the immune reaction to pancreatic cancer from inception to invasion

1 reference

12 December 2020

Secretion of functional hematopoietic growth factors by human carcinoma cell lines

1 reference

12 December 2020

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

1 reference

12 December 2020

Sensitive and quantitative detection of KRAS2 gene mutations in pancreatic duct juice differentiates patients with pancreatic cancer from chronic pancreatitis, potential for early detection

1 reference

12 December 2020

Critical role of neutrophils for the generation of psoriasiform skin lesions in flaky skin mice

1 reference

12 December 2020

10.1016/J.CCR.2012.04.024

Identifiers

DOI

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17 August 2017

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17 August 2017

PubMed publication ID

22698407

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