Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalpha (Q37002231)

17 August 2017

Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalpha (English)

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17 August 2017

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Sara Ribeiro

2

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Jorge P Pinto

object named as

Jorge P Pinto

1

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Graça Porto

object named as

Graça Porto

7

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Félix Carvalho

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Félix Carvalho

6

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author name string

Helena Pontes

3

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17 August 2017

Shifaan Thowfeequ

4

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17 August 2017

David Tosh

5

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17 August 2017

language of work or name

English

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publication date

7 March 2008

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17 August 2017

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17 August 2017

111

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17 August 2017

12

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17 August 2017

5727-5733

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describes a project that uses

17 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2597200/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.

1 reference

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Insulin-like growth factor (IGF)-II regulates CCAAT/enhancer binding protein alpha expression via phosphatidyl-inositol 3 kinase in human hepatoblastoma cell lines

29 September 2017

1 reference

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Regulation of hepcidin in HepG2 and RINm5F cells

29 September 2017

1 reference

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ROS mediate the hypoxic repression of the hepcidin gene by inhibiting C/EBPalpha and STAT-3.

29 September 2017

1 reference

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Downregulation of hepcidin and haemojuvelin expression in the hepatocyte cell-line HepG2 induced by thalassaemic sera.

29 September 2017

1 reference

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Erythropoietin and the cardiorenal syndrome: cellular mechanisms on the cardiorenal connectors

29 September 2017

1 reference

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Suppression of hepcidin during anemia requires erythropoietic activity

29 September 2017

1 reference

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Regulation of iron metabolism by hepcidin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597200

Regulation of erythropoietin production

29 September 2017

1 reference

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The erythropoietin receptor and its expression in tumor cells and other tissues

29 September 2017

1 reference

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C/EBPalpha is a DNA damage-inducible p53-regulated mediator of the G1 checkpoint in keratinocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597200

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597200

Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration

29 September 2017

1 reference

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PI3 kinase is important for Ras, MEK and Erk activation of Epo-stimulated human erythroid progenitors

29 September 2017

1 reference

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IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

29 September 2017

1 reference

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Lithium stabilizes the CCAAT/enhancer-binding protein alpha (C/EBPalpha) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibition of proteasomal activity

29 September 2017

1 reference

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Expression of hepcidin in hereditary hemochromatosis: evidence for a regulation in response to the serum transferrin saturation and to non-transferrin-bound iron

29 September 2017

1 reference

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Is hyperthermia the triggering factor for hepatotoxicity induced by 3,4-methylenedioxymethamphetamine (ecstasy)? An in vitro study using freshly isolated mouse hepatocytes

29 September 2017

1 reference

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Regulated expression and functional role of the transcription factor CHOP (GADD153) in erythroid growth and differentiation.

29 September 2017

1 reference

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Identification of the promoter of the mouse obese gene

29 September 2017

1 reference

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Regulators of iron balance in humans

29 September 2017

1 reference

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CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597200

Erythropoietin regulates tumour growth of human malignancies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597200

C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597200

Effects of recombinant human erythropoietin on haemolytic anaemia in mice

27 June 2018

1 reference

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Feedback modulation of renal and hepatic erythropoietin mRNA in response to graded anemia and hypoxia

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597200

Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597200

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597200

Interleukin-6 inhibits human peroxisome proliferator activated receptor alpha gene expression via CCAAT/enhancer-binding proteins in hepatocytes

20 October 2018

1 reference

12 December 2020

Hepcidin, a new iron regulatory peptide

1 reference

12 December 2020

Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression

1 reference

12 December 2020

Isolation and use of liver cells

1 reference

12 December 2020

Organ distribution of erythropoietin messenger RNA in normal and uremic rats

1 reference

12 December 2020

Re-expression of C/EBPα induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells

1 reference

12 December 2020

10.1182/BLOOD-2007-08-106195

Identifiers

DOI

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

18326822

1 reference