Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease. (Q36998284)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23634965 AND SRC:MED&resulttype=core&format=json

29 February 2020

title

Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease (English)

1 reference

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29 February 2020

0 references

0 references

mild cognitive impairment

1 reference

inferred from title

cognitive dysfunction

1 reference

4

1 reference

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29 February 2020

William Hu

3

1 reference

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29 February 2020

author name string

Termpanit Chalermpalanupap

1

1 reference

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29 February 2020

Becky Kinkead

2

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29 February 2020

Thea Hammerschmidt

5

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29 February 2020

Michael T Heneka

6

1 reference

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29 February 2020

David Weinshenker

7

1 reference

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29 February 2020

Allan I Levey

8

1 reference

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29 February 2020

language of work or name

English

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publication date

29 April 2013

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Alzheimers Research & Therapy

29 February 2020

published in

1 reference

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29 February 2020

volume

5

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29 February 2020

issue

2

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29 February 2020

page(s)

21

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Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers.

29 February 2020

cites work

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The relationship between subcortical tau pathology and Alzheimer's disease.

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Common factors among Alzheimer's disease, Parkinson's disease, and epilepsy: possible role of the noradrenergic nervous system

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Norepinephrine differentially modulates the innate inflammatory response provoked by amyloid-β peptide via action at β-adrenoceptors and activation of cAMP/PKA pathway in human THP-1 macrophages

29 September 2017

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The noradrenaline precursor L-DOPS reduces pathology in a mouse model of Alzheimer's disease

29 September 2017

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Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis

29 September 2017

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Complement 3 and factor h in human cerebrospinal fluid in Parkinson's disease, Alzheimer's disease, and multiple-system atrophy

29 September 2017

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Decreased clearance of CNS beta-amyloid in Alzheimer's disease

29 September 2017

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The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project

29 September 2017

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Chronic treatment with the α2-adrenoceptor antagonist fluparoxan prevents age-related deficits in spatial working memory in APP×PS1 transgenic mice without altering β-amyloid plaque load or astrocytosis.

29 September 2017

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Norepinephrine promotes microglia to uptake and degrade amyloid beta peptide through upregulation of mouse formyl peptide receptor 2 and induction of insulin-degrading enzyme.

29 September 2017

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Atomoxetine for depression and other neuropsychiatric symptoms in Parkinson disease

29 September 2017

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Biomarker discovery for Alzheimer's disease, frontotemporal lobar degeneration, and Parkinson's disease

29 September 2017

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Changes in B- and T-lymphocyte and chemokine levels with rituximab treatment in multiple sclerosis.

29 September 2017

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Biomarkers of oxidative damage and inflammation in Alzheimer's disease

29 September 2017

1 reference

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Novel CSF biomarkers for Alzheimer's disease and mild cognitive impairment

29 September 2017

1 reference

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Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

29 September 2017

1 reference

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Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity

29 September 2017

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The neuropsychopharmacology of fronto-executive function: monoaminergic modulation

29 September 2017

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The locus coeruleus and noradrenergic modulation of cognition

29 September 2017

1 reference

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Atomoxetine for the treatment of executive dysfunction in Parkinson's disease: a pilot open-label study.

29 September 2017

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Effects of cardiovascular medications on rate of functional decline in Alzheimer disease.

29 September 2017

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Functional consequences of locus coeruleus degeneration in Alzheimer's disease

29 September 2017

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Adrenergic pharmacology and cognition: focus on the prefrontal cortex

29 September 2017

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Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms.

29 September 2017

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Inflammation in Alzheimer disease: driving force, bystander or beneficial response?

29 September 2017

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29 September 2017

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Efficacy of atomoxetine in adult attention-deficit/hyperactivity disorder: a drug-placebo response curve analysis

29 September 2017

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Noradrenergic regulation of inflammatory gene expression in brain.

29 September 2017

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The novel beta-blocker, carvedilol, provides neuroprotection in transient focal stroke

29 September 2017

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Mice lacking the norepinephrine transporter are supersensitive to psychostimulants

29 September 2017

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Role of norepinephrine in the pathophysiology and treatment of mood disorders

29 September 2017

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Amyloid precursor protein in the cerebral cortex is rapidly and persistently induced by loss of subcortical innervation

29 September 2017

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Neurobiologic bases of noncognitive behavioral problems in Alzheimer disease.

29 September 2017

1 reference

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Disease-specific patterns of locus coeruleus cell loss

29 September 2017

1 reference

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The locus coeruleus: neurobiology of a central noradrenergic nucleus

29 September 2017

1 reference

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Relationships Between Behavioral Syndromes and Cognitive Domains in Alzheimer Disease: The Impact of Mood and Psychosis

29 September 2017

1 reference

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Effect of atomoxetine on executive function impairments in adults with ADHD.

27 June 2018

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Interaction between dopamine beta-hydroxylase and interleukin genes increases Alzheimer's disease risk

27 June 2018

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Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease.

27 June 2018

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Clonidine impairs sustained attention and memory in Alzheimer's disease

27 June 2018

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THA improves word priming and clonidine enhances fluency and working memory in Alzheimer's disease

27 June 2018

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β2-Adrenoceptors on the glial cells mediate the induction of interleukin-1β mRNA in the rat brain

27 June 2018

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Low-dose propranolol reduces aggression and agitation resembling that associated with orbitofrontal dysfunction in elderly demented patients.

27 June 2018

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Disproportionate loss of noradrenergic and cholinergic neurons as cause of depression in Alzheimer's disease--a hypothesis

27 June 2018

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Norepinephrine and MHPG levels in CSF and plasma in Alzheimer's disease

27 June 2018

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Propranolol treatment of assaultive patients with organic brain disease. A double-blind crossover, placebo-controlled study

27 June 2018

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Neuronal degeneration in locus ceruleus and cortical correlates of Alzheimer disease.

27 June 2018

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Catecholamine system involvement in age-related memory dysfunction

27 June 2018

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Alterations in catecholamine neurons of the locus coeruleus in senile dementia of the Alzheimer type and in Parkinson's disease with and without dementia and depression.

27 June 2018

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Locus Coeruleus Lesions and Learning

27 June 2018

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Histochemical characterization of a neocortical projection of the nucleus locus coeruleus in the squirrel monkey

27 June 2018

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Investigation of nebivolol as a novel therapeutic agent for the treatment of Alzheimer's disease

27 June 2018

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Nebivolol and metoprolol: long-term effects on inflammation and oxidative stress in essential hypertension

4 September 2018

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Distinct adrenergic system changes and neuroinflammation in response to induced locus ceruleus degeneration in APP/PS1 transgenic mice

4 September 2018

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Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice.

4 September 2018

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Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits

4 September 2018

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Regulation of MCP-1 production in brain by stress and noradrenaline-modulating drugs.

4 September 2018

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Improvement of executive functions in boys with attention deficit hyperactivity disorder: an open-label follow-up study with once-daily atomoxetine

4 September 2018

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Atomoxetine augmentation of cholinesterase inhibitor therapy in patients with Alzheimer disease: 6-month, randomized, double-blind, placebo-controlled, parallel-trial study

4 September 2018

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Memory loss caused by beta-amyloid protein is rescued by a beta(3)-adrenoceptor agonist

4 September 2018

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Role of central beta-adrenergic receptors in regulating proinflammatory cytokine responses to a peripheral bacterial challenge

4 September 2018

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Polymorphisms at the beta2-adrenergic receptor gene influence Alzheimer's disease susceptibility.

4 September 2018

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Locus ceruleus degeneration is ubiquitous in Alzheimer's disease: possible implications for diagnosis and treatment

4 September 2018

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GGA1 is expressed in the human brain and affects the generation of amyloid beta-peptide.

4 September 2018

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Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease

4 September 2018

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Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease

4 September 2018

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Antihypertensive medication use and incident Alzheimer disease: the Cache County Study.

4 September 2018

1 reference

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Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy bodies.

4 September 2018

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Atomoxetine and stroop task performance in adult attention-deficit/hyperactivity disorder

4 September 2018

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Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines.

4 September 2018

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Cross-sectional and longitudinal association between antihypertensive medications and cognitive impairment in an elderly population

4 September 2018

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Polymorphism in genes involved in adrenergic signaling associated with Alzheimer's.

4 September 2018

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Gender differences in the amount and deposition of amyloidbeta in APPswe and PS1 double transgenic mice

4 September 2018

1 reference

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Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases

4 September 2018

1 reference

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Neuron loss in key cholinergic and aminergic nuclei in Alzheimer disease: a meta-analysis

4 September 2018

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Effects of Alzheimer's disease severity on cerebrospinal fluid norepinephrine concentration

4 September 2018

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Neuropathological correlates of psychotic phenomena in confirmed Alzheimer's disease

4 September 2018

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Effects of Alzheimer's Disease and Normal Aging on Cerebrospinal Fluid Norepinephrine Responses to Yohimbine and Clonidine

4 September 2018

1 reference

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Participation of cAMP and cAMP-dependent protein kinase in beta-adrenoceptor-mediated interleukin-1 beta mRNA induction in cultured microglia.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706916

Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and down's syndrome

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706916

Changes in the Monoamine Containing Neurones of the Human Cns in Senile Dementia

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706916

Noradrenergic mechanisms in neurodegenerative diseases: a theory

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3706916

Natalizumab treatment in multiple sclerosis: marked decline of chemokines and cytokines in cerebrospinal fluid

4 December 2018

1 reference

12 December 2020

Anti-inflammatory potential of curcumin and quercetin in rats: role of oxidative stress, heme oxygenase-1 and TNF-α

1 reference

12 December 2020

The pathological process underlying Alzheimer's disease in individuals under thirty

1 reference

12 December 2020

Double-blind trial of imipramine in Alzheimer's disease patients with and without depression

1 reference

12 December 2020

The locus coeruleus–noradrenergic system: modulation of behavioral state and state-dependent cognitive processes

1 reference

12 December 2020

Identifiers

DOI

10.1186/ALZRT175

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23634965 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23634965 AND SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

23634965

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23634965 AND SRC:MED&resulttype=core&format=json