RAB and RHO GTPases regulate intestinal crypt cell homeostasis and enterocyte function. (Q36997840)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27142493 AND SRC:MED&resulttype=core&format=json

3 April 2020

review article

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title

RAB and RHO GTPases regulate intestinal crypt cell homeostasis and enterocyte function (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27142493 AND SRC:MED&resulttype=core&format=json

3 April 2020

1

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3 April 2020

author name string

Nan Gao

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27142493 AND SRC:MED&resulttype=core&format=json

3 April 2020

language of work or name

1 reference

1 April 2016

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27142493 AND SRC:MED&resulttype=core&format=json

3 April 2020

published in

Small GTPases (journal)

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3 April 2020

volume

7

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3 April 2020

issue

2

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3 April 2020

page(s)

59-64

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Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3.

3 April 2020

cites work

1 reference

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An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking

29 September 2017

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Myo5b knockout mice as a model of microvillus inclusion disease.

29 September 2017

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Fructose-induced increases in expression of intestinal fructolytic and gluconeogenic genes are regulated by GLUT5 and KHK.

29 September 2017

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Transport, metabolism, and endosomal trafficking-dependent regulation of intestinal fructose absorption

29 September 2017

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Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche.

29 September 2017

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A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer

29 September 2017

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Rab11a regulates syntaxin 3 localization and microvillus assembly in enterocytes

29 September 2017

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Keeping Wnt signalosome in check by vesicular traffic

29 September 2017

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Global ablation of the mouse Rab11a gene impairs early embryogenesis and matrix metalloproteinase secretion

29 September 2017

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CDC42 inhibition suppresses progression of incipient intestinal tumors

29 September 2017

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TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis

29 September 2017

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Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease

29 September 2017

1 reference

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Loss of syntaxin 3 causes variant microvillus inclusion disease

29 September 2017

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Wnt secretion from epithelial cells and subepithelial myofibroblasts is not required in the mouse intestinal stem cell niche in vivo.

29 September 2017

1 reference

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Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

Cdc42 coordinates proliferation, polarity, migration, and differentiation of small intestinal epithelial cells in mice

29 September 2017

1 reference

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Wntless in Wnt secretion: molecular, cellular and genetic aspects

29 September 2017

1 reference

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Paneth cells: maestros of the small intestinal crypts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

Cdc42 interacts with the exocyst complex to promote phagocytosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1).

29 September 2017

1 reference

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Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

Interconversion between intestinal stem cell populations in distinct niches

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

Lgr5( ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

29 September 2017

1 reference

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MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity.

29 September 2017

1 reference

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The yeast actin cytoskeleton: from cellular function to biochemical mechanism

29 September 2017

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Wnt control of stem cells and differentiation in the intestinal epithelium

29 September 2017

1 reference

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Self-renewal and cancer of the gut: two sides of a coin.

29 September 2017

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Wnt signalling induces maturation of Paneth cells in intestinal crypts

29 September 2017

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Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud

29 September 2017

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Cdc42 interacts with the exocyst and regulates polarized secretion.

29 September 2017

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The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis

29 September 2017

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Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane

29 September 2017

1 reference

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Microvillus inclusion disease: an inherited defect of brush-border assembly and differentiation

29 September 2017

1 reference

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Familial enteropathy: A syndrome of protracted diarrhea from birth, failure to thrive, and hypoplastic villus atrophy

29 September 2017

1 reference

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Rab11a is required for apical protein localisation in the intestine.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

The localisation of the apical Par/Cdc42 polarity module is specifically affected in microvillus inclusion disease.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

Yap-dependent reprogramming of Lgr5( ) stem cells drives intestinal regeneration and cancer

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

Genetic variants in CDC42 and NXPH1 as susceptibility factors for constipation and diarrhoea predominant irritable bowel syndrome

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

RAB8B is required for activity and caveolar endocytosis of LRP6.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

Navajo microvillous inclusion disease is due to a mutation in MYO5B.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

The Rab8 GTPase regulates apical protein localization in intestinal cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4905260

10.1080/21541248.2016.1159274

4 September 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27142493 AND SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27142493 AND SRC:MED&resulttype=core&format=json

3 April 2020

PubMed publication ID

27142493

1 reference