Regulatory T cells - a brief history and perspective (Q36986732)

17 August 2017

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title

Regulatory T cells - a brief history and perspective (English)

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17 August 2017

Kajsa Wing

2

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Shimon Sakaguchi

series ordinal

1

object named as

Shimon Sakaguchi

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17 August 2017

Makoto Miyara

3

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17 August 2017

language of work or name

English

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publication date

1 November 2007

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European Journal of Immunology

17 August 2017

published in

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17 August 2017

volume

37 Suppl 1

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17 August 2017

page(s)

S116-23

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Regulatory T cells: key controllers of immunologic self-tolerance

17 August 2017

cites work

1 reference

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7 January 2021

Immunoregulatory T-cell pathways.

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7 January 2021

RNA transcripts for I-J polypeptides are apparently not encoded between the I-A and I-E subregions of the murine major histocompatibility complex

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7 January 2021

Revisiting and revising suppressor T cells

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7 January 2021

T cell tolerance by clonal elimination in the thymus

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7 January 2021

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4 8 thymocytes

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7 January 2021

Self-tolerance checkpoints in B lymphocyte development

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7 January 2021

Role of cytokines in determining T-lymphocyte function

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7 January 2021

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

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7 January 2021

A CD4 T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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7 January 2021

Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice

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7 January 2021

Genetic susceptibility to post-thymectomy autoimmune diseases in mice.

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7 January 2021

Induction of diabetes in PVG/c strain rats by manipulation of the immune system

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7 January 2021

Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4 T cell subset that inhibits this autoimmune potential

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7 January 2021

Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis

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Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer

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Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease

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7 January 2021

OX-22high CD4 T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset

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7 January 2021

Adoptive transfer of autoimmune diabetes and thyroiditis to athymic rats

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7 January 2021

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

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7 January 2021

Phenotypically distinct subsets of CD4 T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

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7 January 2021

CD4 T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4 T cells

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7 January 2021

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

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7 January 2021

Homeostasis of peripheral CD4 T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4 T cell numbers

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7 January 2021

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

1 reference

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7 January 2021

Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo

1 reference

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7 January 2021

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

1 reference

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7 January 2021

Homeostatic maintenance of natural Foxp3( ) CD25( ) CD4( ) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Immunologic self-tolerance maintained by CD25 CD4 naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

CD4 CD25 immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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7 January 2021

Certified professionals: CD4( )CD25( ) suppressor T cells

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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7 January 2021

JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

1 reference

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7 January 2021

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Control of regulatory T cell development by the transcription factor Foxp3

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Foxp3 programs the development and function of CD4 CD25 regulatory T cells

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

An essential role for Scurfin in CD4 CD25 T regulatory cells

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Selective depletion of Foxp3 regulatory T cells induces a scurfy-like disease

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Analysis of FOXP3 protein expression in human CD4 CD25 regulatory T cells at the single-cell level

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells.

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

FOXP3 controls regulatory T cell function through cooperation with NFAT

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1

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7 January 2021

Regulatory T cells in the control of immune pathology.

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Mechanisms of suppression by suppressor T cells

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Conversion of peripheral CD4 CD25- naive T cells to CD4 CD25 regulatory T cells by TGF-beta induction of transcription factor Foxp3

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

In vivo instruction of suppressor commitment in naive T cells

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Crucial role of FOXP3 in the development and function of human CD25 CD4 regulatory T cells

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Direct expansion of functional CD25 CD4 regulatory T cells by antigen-processing dendritic cells

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Control of Foxp3 CD25 CD4 regulatory cell activation and function by dendritic cells

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Toll pathway-dependent blockade of CD4 CD25 T cell-mediated suppression by dendritic cells

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Foxp3 CD25 CD4 natural regulatory T cells in dominant self-tolerance and autoimmune disease

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Naturally arising CD4 regulatory t cells for immunologic self-tolerance and negative control of immune responses

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

"Infectious" transplantation tolerance.

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. III. Further characterization of the CD4 suppressor cell and its mechanisms of action

1 reference

https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Infectious tolerance and the long-term acceptance of transplanted tissue

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

From vanilla to 28 flavors: multiple varieties of T regulatory cells

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https://api.crossref.org/works/10.1002/EJI.200737593

7 January 2021

Identifiers

DOI

10.1002/EJI.200737593

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17 August 2017

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