Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome (Q36967955)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18775956 AND SRC:MED&resulttype=core&format=json

13 January 2020

title

Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome (English)

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Smith-Lemli-Opitz syndrome

13 January 2020

main subject

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2

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13 January 2020

8

Alan T Remaley

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13 January 2020

author name string

Marie L Lindegaard

1

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13 January 2020

Boris Vaisman

3

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13 January 2020

Marcelo Amar

4

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13 January 2020

Elizabeth V Wasmuth

5

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13 January 2020

Robert Shamburek

6

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13 January 2020

Lars B Nielsen

7

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13 January 2020

Forbes D Porter

9

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13 January 2020

publication date

5 September 2008

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13 January 2020

published in

Human Molecular Genetics

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13 January 2020

volume

17

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13 January 2020

issue

23

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13 January 2020

page(s)

3806-3813

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Enhanced placental cholesterol efflux by fetal HDL in Smith-Lemli-Opitz syndrome

13 January 2020

cites work

1 reference

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Smith-Lemli-Opitz syndrome: pathogenesis, diagnosis and management

29 September 2017

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Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice

29 September 2017

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Cholesterol transport by the placenta: placental liver X receptor activity as a modulator of fetal cholesterol metabolism?

29 September 2017

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29 September 2017

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Liver X receptors mediate inhibition of hCG secretion in a human placental trophoblast cell line

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Residual cholesterol synthesis and simvastatin induction of cholesterol synthesis in Smith-Lemli-Opitz syndrome fibroblasts

29 September 2017

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Placental expression of the nuclear receptors for oxysterols LXRalpha and LXRbeta during mouse and human development.

29 September 2017

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Maternal apo E genotype is a modifier of the Smith-Lemli-Opitz syndrome.

29 September 2017

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ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

29 September 2017

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Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure

29 September 2017

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Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues.

29 September 2017

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LXRs; oxysterol-activated nuclear receptors that regulate genes controlling lipid homeostasis

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Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

29 September 2017

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Comparative developmental anatomy of the murine and human definitive placentae.

29 September 2017

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Abnormal lipoprotein metabolism and reversible female infertility in HDL receptor (SR-BI)-deficient mice

29 September 2017

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Biochemical, phenotypic and neurophysiological characterization of a genetic mouse model of RSH/Smith--Lemli--Opitz syndrome

29 September 2017

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Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency

29 September 2017

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ABCA1-mediated transport of cellular cholesterol and phospholipids to HDL apolipoproteins

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Diagnosis of Smith-Lemli-Opitz syndrome by gas chromatography/mass spectrometry of 7-dehydrocholesterol in plasma, amniotic fluid and cultured skin fibroblasts

29 September 2017

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Cholesterol Metabolism and Placental Transfer in the Pregnant Rhesus Monkey

29 September 2017

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29 September 2017

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Tissue-specific autoregulation of the LXRalpha gene facilitates induction of apoE in mouse adipose tissue

29 September 2017

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27 June 2018

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27 June 2018

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Placental transfer of cholesterol into the human fetus

27 June 2018

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27 June 2018

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Effect of probucol on HDL metabolism and class B type I scavenger receptor (SR-BI) expression in the liver of hypercholesterolemic rabbits.

4 September 2018

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Regulatory effects of synthetic liver X receptor- and peroxisome-proliferator activated receptor agonists on sterol transport pathways in polarized cerebrovascular endothelial cells

4 September 2018

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ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation

4 September 2018

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4 September 2018

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4 September 2018

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Antenatal therapy of Smith-Lemli-Opitz syndrome

4 September 2018

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4 September 2018

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Inhibition of progesterone production in human luteinized granulosa cells treated with LXR agonists

4 September 2018

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Expression of mouse alpha-macroglobulins, lipoprotein receptor-related protein, LDL receptor, apolipoprotein E, and lipoprotein lipase in pregnancy

4 December 2018

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12 December 2020

Temporal and spatial pattern of expression of the HDL receptor SR-BI during murine embryogenesis

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12 December 2020

Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface

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Placental ABCA1 expression is reduced in primary antiphospholipid syndrome compared to pre-eclampsia and controls

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Identifiers

DOI

10.1093/HMG/DDN278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18775956 AND SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18775956 AND SRC:MED&resulttype=core&format=json

13 January 2020

PubMed publication ID

18775956

1 reference