Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus. (Q36951816)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27183387 AND SRC:MED&resulttype=core&format=json

1 April 2020

title

Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27183387 AND SRC:MED&resulttype=core&format=json

systemic lupus erythematosus

1 April 2020

main subject

0 references

author

Masayuki Mizui

2

1 reference

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1 April 2020

author name string

Jianxun Wang

1

1 reference

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1 April 2020

Li-Fan Zeng

3

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1 April 2020

Roderick Bronson

4

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1 April 2020

Michele Finnell

5

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1 April 2020

Cox Terhorst

6

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1 April 2020

Vasileios C Kyttaris

7

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1 April 2020

George C Tsokos

8

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1 April 2020

Zhong-Yin Zhang

9

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1 April 2020

Maria I Kontaridis

10

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1 April 2020

language of work or name

English

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publication date

16 May 2016

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Journal of Clinical Investigation

1 April 2020

published in

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volume

126

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issue

6

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1 April 2020

page(s)

2077-2092

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describes a project that uses

1 April 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4887187/fullTextXML

inferred from PubMed Central ID database lookup

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation

9 September 2017

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The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors

29 September 2017

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29 September 2017

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29 September 2017

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Diverse biochemical properties of Shp2 mutants. Implications for disease phenotypes

29 September 2017

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Th1 (IL-2, interferon-gamma (IFN-gamma)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE).

27 June 2018

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Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2.

27 June 2018

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Genetic analysis of protein tyrosine phosphatases

27 June 2018

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Inhibition of PI3Kδ reduces kidney infiltration by macrophages and ameliorates systemic lupus in the mouse

27 June 2018

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4 September 2018

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Epidemiology: Interpreting studies of interactions between RA risk factors

4 September 2018

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Noonan syndrome associated with systemic lupus erythematosus

4 September 2018

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Protein tyrosine phosphatase non-receptor type 22 gene variants at position 1858 are associated with type 1 and type 2 diabetes in Estonian population

4 September 2018

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Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling

4 September 2018

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4 September 2018

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Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

4 September 2018

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Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice

4 September 2018

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Experimental therapy of systemic lupus erythematosus: the treatment of NZB/W mice with mouse soluble interferon-gamma receptor inhibits the onset of glomerulonephritis

4 September 2018

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Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus

20 October 2018

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12 December 2020

Systemic lupus erythematosus in a man with Noonan syndrome

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12 December 2020

Impaired T cell protein kinase C delta activation decreases ERK pathway signaling in idiopathic and hydralazine-induced lupus

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12 December 2020

The unusual association of three autoimmune diseases in a patient with Noonan syndrome

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12 December 2020

Noonan syndrome and systemic lupus erythematosus in a patient with a novel KRAS mutation

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12 December 2020

Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients

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12 December 2020

Monocyte chemoattractant protein-1 expression in renal tissue is associated with monocyte recruitment and tubulo-interstitial lesions in patients with lupus nephritis

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12 December 2020

Cardiologic abnormalities in Noonan syndrome: phenotypic diagnosis and echocardiographic assessment of 118 patients

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12 December 2020

Systemic lupus erythematosus and other autoimmune disorders in children with Noonan syndrome

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12 December 2020

Genomic view of systemic autoimmunity in MRLlpr mice

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12 December 2020

Noonan syndrome and systemic lupus erythematosus: presentation in childhood

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12 December 2020

Rapamycin prolongs survival and arrests pathophysiologic changes in murine systemic lupus erythematosus

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12 December 2020

Increased interferon-gamma (IFN-gamma), IL-10 and decreased IL-4 mRNA expression in peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE)

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12 December 2020

Identifiers

DOI

10.1172/JCI87037

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27183387 AND SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27183387 AND SRC:MED&resulttype=core&format=json

1 April 2020

PubMed publication ID

27183387

1 reference