Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla (Q36946557)

17 August 2017

Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla (English)

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17 August 2017

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Kristin A Hogquist

4

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author name string

Tom M McCaughtry

series ordinal

1

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17 August 2017

Troy A Baldwin

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2

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17 August 2017

Matthew S Wilken

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3

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17 August 2017

language of work or name

English

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publication date

20 October 2008

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Journal of Experimental Medicine

17 August 2017

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17 August 2017

205

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17 August 2017

11

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17 August 2017

2575-2584

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describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2571932/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Generating intrathymic microenvironments to establish T-cell tolerance.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

A constant affinity threshold for T cell tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Impaired responsiveness to T-cell receptor stimulation and defective negative selection of thymocytes in CCR7-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Selection of Foxp3 regulatory T cells specific for self antigen expressed and presented by Aire medullary thymic epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Developmental regulation of Foxp3 expression during ontogeny.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Central tolerance: learning self-control in the thymus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

The timing of TCR alpha expression critically influences T cell development and selection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Dependence of self-tolerance on TRAF6-directed development of thymic stroma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

In vivo depletion of CD11c dendritic cells abrogates priming of CD8 T cells by exogenous cell-associated antigens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Detection of apoptosis in tissue sections.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Thymus epithelium induces tissue-specific tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Lymphocytes selected in allogeneic thymic epithelium mediate dominant tolerance toward tissue grafts of the thymic epithelium haplotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

An essential role for gp39, the ligand for CD40, in thymic selection.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Deletion of high-avidity T cells by thymic epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Induction of tolerance by embryonic thymic epithelial grafts in birds and mammals

29 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

29 September 2017

https://api.crossref.org/works/10.1084/JEM.20080866

TCR signaling regulates thymic organization: lessons from TCR-transgenic mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Negative selection of precursor thymocytes before their differentiation into CD4 CD8 cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Rat Thymic Epithelium Positively Selects Mouse T Cells with Specificity for Rat MHC Class II Antigens but Fails to Induce Detectable Tolerance in the Mouse T Cells to the Rat MHC Antigens

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Developmental alterations in thymocyte sensitivity are actively regulated by MHC class II expression in the thymic medulla

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Negative selection of the T-cell repertoire: where and when does it occur?

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

CCR7 signals are essential for cortex-medulla migration of developing thymocytes.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

The influence of the thymic environment on the CD4-versus-CD8 T lineage decision.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Thymocyte apoptosis induced by T cell activation is mediated by glucocorticoids in vivo

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Early TCRalpha expression generates TCRalphagamma complexes that signal the DN-to-DP transition and impair development.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2571932

Direct Visualization of thymocyte apoptosis in neglect, acute and steady-state negative selection

4 September 2018

1 reference

https://api.crossref.org/works/10.1084/JEM.20080866

Minor but not major histocompatibility antigens of thymus epithelium tolerize precursors of cytolytic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084/JEM.20080866

Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1084/JEM.20080866

Thymic epithelium and the induction of transplantation tolerance in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084/JEM.20080866

T-cell apoptosis detected in situ during positive and negative selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084/JEM.20080866

Thymic cortical epithelium induces self tolerance

21 January 2018

1 reference

12 December 2020

Altered thymocyte development resulting from expressing a deleting ligand on selecting thymic epithelium

1 reference

12 December 2020

Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation

1 reference

12 December 2020

Dissociation of thymic positive and negative selection in transgenic mice expressing major histocompatibility complex class I molecules exclusively on thymic cortical epithelial cells

1 reference

12 December 2020

Premature TCR alpha beta expression and signaling in early thymocytes impair thymocyte expansion and partially block their development

1 reference

12 December 2020

Central tolerance to self-antigen expressed by cortical epithelial cells

1 reference

12 December 2020

Tolerogenicity of thymic epithelium

1 reference

12 December 2020

Selection of the T-cell repertoire in transgenic mice expressing a transplantation antigen in distinct thymus subsets

1 reference

12 December 2020

Anergy induced by thymic medullary epithelium

1 reference

12 December 2020

CD40 is functionally expressed on human thymic epithelial cells

1 reference

12 December 2020

Normal sequence of phenotypic transitions in one cohort of 5-bromo-2'-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression

1 reference

12 December 2020

The costimulatory molecule B7 is expressed in the medullary region of the murine thymus

1 reference

12 December 2020

Antigen‐specific and nonspecific deletion of immature cortical thymocytes caused by antigen injection

1 reference

12 December 2020

Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance

1 reference

12 December 2020

Transcriptional analysis of clonal deletion in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20080866

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

18936237

1 reference