Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study. (Q36941044)

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9 January 2020

title

Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study (English)

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9 January 2020

1 reference

1 reference

diffuse large B-cell lymphoma

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17

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Michael Boe Møller

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Gisele W B Colleoni

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Miguel A. Piris

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Elías Campo

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Julie M Vose

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Randy D Gascoyne

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Wing C Chan

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Dennis D Weisenburger

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object named as

Dennis D Weisenburger

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Andreas Rosenwald

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Elaine S Jaffe

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Wyndham H Wilson

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Lisa Rimsza

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Rita M Braziel

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Philippe Gaulard

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Timothy C Greiner

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14

Brad S Kahl

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Ken H Young

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author name string

Fábio R Kerbauy

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Jens C Eickhoff

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Allen H Young

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Terry D Oberley

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William M Rehrauer

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James S Malter

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James Huang

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Louis M Staudt

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language of work or name

English

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publication date

17 June 2008

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9 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559976 AND SRC:MED&resulttype=core&format=json

9 January 2020

volume

112

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9 January 2020

issue

8

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9 January 2020

page(s)

3088-3098

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Mutations in the DNA-binding codons of TP53, which are associated with decreased expression of TRAILreceptor-2, predict for poor survival in diffuse large B-cell lymphoma

9 January 2020

cites work

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Mutant p53 proteins: between loss and gain of function

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CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group

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Repression of the MSP/MST-1 gene contributes to the antiapoptotic gain of function of mutant p53

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What have animal models taught us about the p53 pathway?

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Modelling clustered survival data from multicentre clinical trials

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Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray

29 September 2017

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Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma

29 September 2017

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Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

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Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

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TP53 in hematological cancer: low incidence of mutations with significant clinical relevance

29 September 2017

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Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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'Gain of function' phenotype of tumor-derived mutant p53 requires the oligomerization/nonsequence-specific nucleic acid-binding domain

29 September 2017

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Activation of c-myc Gene Expression by Tumor-Derived p53 Mutants Requires a Discrete C-Terminal Domain

29 September 2017

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A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. The Non-Hodgkin's Lymphoma Classification Project

29 September 2017

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p53, the cellular gatekeeper for growth and division

29 September 2017

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Transcriptional activation of the human epidermal growth factor receptor promoter by human p53.

29 September 2017

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The p53 tumour suppressor gene: a model for molecular epidemiology of human cancer

29 September 2017

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Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene

29 September 2017

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29 September 2017

p53: puzzle and paradigm

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High levels of p53 protein expression do not correlate with p53 gene mutations in anaplastic large cell lymphoma

29 September 2017

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

29 September 2017

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Hot-spot p53 mutants interact specifically with two cellular proteins during progression of the cell cycle

29 September 2017

1 reference

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p53 mutations in human cancers

29 September 2017

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Modulation of cellular and viral promoters by mutant human p53 proteins found in tumor cells

29 September 2017

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Overall survival in aggressive B-cell lymphomas is dependent on the accumulation of alterations in p53, p16, and p27.

29 September 2017

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The clinical significance of mutations of the P53 tumour suppressor gene in haematological malignancies

27 June 2018

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Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.

27 June 2018

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Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma

27 June 2018

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Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression.

27 June 2018

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Gain of function mutations in p53.

27 June 2018

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p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

27 June 2018

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Analysis of TP53 gene mutations in human lung cancer: comparison of capillary electrophoresis single strand conformation polymorphism assay with denaturing gradient gel electrophoresis and direct sequencing.

4 September 2018

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Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

4 September 2018

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The impact of p53 protein core domain structural alteration on ovarian cancer survival

4 September 2018

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The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.

4 September 2018

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Simultaneous use of DGGE and DHPLC to screen TP53 mutations in cancers of the esophagus and cardia from a European high incidence area (Lower Normandy, France).

4 September 2018

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p53 gene mutations are associated with poor survival in low and low-intermediate risk diffuse large B-cell lymphomas.

4 September 2018

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Aberrations of the p53 pathway components p53, MDM2 and CDKN2A appear independent in diffuse large B cell lymphoma.

4 September 2018

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The 273rd codon mutants of p53 show growth modulation activities not correlated with p53-specific transactivation activity.

4 September 2018

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TP53 mutations and breast cancer prognosis: particularly poor survival rates for cases with mutations in the zinc-binding domains.

4 September 2018

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p53 status and the efficacy of cancer therapy in vivo

4 September 2018

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12 December 2020

p53 gene status as a predictor of tumor response to induction chemotherapy of patients with locoregionally advanced squamous cell carcinomas of the head and neck

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12 December 2020

Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

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12 December 2020

New concepts in treatment approaches and prognostic factors in aggressive NHL

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12 December 2020

TP53 in gastric cancer: mutations in the l3 loop and LSH motif DNA-binding domains of TP53 predict poor outcome

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12 December 2020

Influence of p53 mutation on pathological grade, but not prognosis of non-Hodgkin's lymphoma

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12 December 2020

Promoter hypermethylation of the DNA-repair gene O6-methylguanine-DNA methyltransferase and p53 mutation in diffuse large B-cell lymphoma

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12 December 2020

TP53 DNA contact mutations are selectively associated with allelic loss and have a strong clinical impact in head and neck cancer

1 reference

12 December 2020

Maintenance therapy with rituximab leads to a significant prolongation of response duration after salvage therapy with a combination of rituximab, fludarabine, cyclophosphamide, and mitoxantrone (R-FCM) in patients with recurring and refractory foll

1 reference

12 December 2020

p53 mutation is associated with progression in follicular lymphomas

1 reference

12 December 2020

p53 mutations in mantle cell lymphoma are associated with variant cytology and predict a poor prognosis

1 reference

12 December 2020

Prognostic-significance of p53 mutations in small non-cleaved cell lymphomas

1 reference

12 December 2020

Modulation of the human interleukin-6 promoter (IL-6) and transcription factor C/EBP beta (NF-IL6) activity by p53 species

1 reference

12 December 2020

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

1 reference

12 December 2020

TP53 and long-term prognosis in colorectal cancer: mutations in the L3 zinc-binding domain predict poor survival

1 reference

12 December 2020

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

12 December 2020

Correlation between mutation in P53, p53 expression, cytogenetics, histologic type, and survival in patients with B-cell non-Hodgkin's lymphoma

1 reference

12 December 2020

10.1182/BLOOD-2008-01-129783

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559976 AND SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559976 AND SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

18559976

1 reference