Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations (Q36939821)

17 August 2017

0 references

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations (English)

1 reference

inflammatory bowel diseases

17 August 2017

0 references

0 references

1 reference

30

Harm-Jan Westra

0 references

Hailiang Huang

Hailiang Huang

3

0 references

James Lee

James C Lee

8

0 references

Behrooz Z. Alizadeh

Behrooz Z Alizadeh

36

0 references

Jeffrey Barrett

Jeffrey C Barrett

35

0 references

Siew Chien Ng

Siew C Ng

4

0 references

William G. Newman

William G Newman

23

0 references

Jae Hee Cheon

Jae Hee Cheon

12

0 references

Won Ho Kim

Won Ho Kim

20

0 references

Carl A Anderson

Carl A Anderson

41

0 references

Mark Joseph Daly

39

Mark J Daly

1 reference

17 August 2017

2

Suzanne van Sommeren

1 reference

17 August 2017

42

Rinse K Weersma

1 reference

17 August 2017

7

Stephan Ripke

1 reference

17 August 2017

13

Judy Cho

1 reference

17 August 2017

40

Michiaki Kubo

1 reference

17 August 2017

29

Reza Malekzadeh

1 reference

17 August 2017

32

Suk-Kyun Yang

1 reference

17 August 2017

6

Atsushi Takahashi

1 reference

17 August 2017

17

Ailsa Hart

1 reference

17 August 2017

21

Andrew P Morris

1 reference

17 August 2017

24

Vandana Midha

1 reference

17 August 2017

22

Hossein Poustchi

1 reference

17 August 2017

11

Shifteh Abedian

1 reference

17 August 2017

9

Luke Jostins

1 reference

17 August 2017

Jimmy Z Liu

1

1 reference

17 August 2017

Rudi Alberts

5

1 reference

17 August 2017

Tejas Shah

10

1 reference

17 August 2017

Naser E Dayani

14

1 reference

17 August 2017

Lude Franke

15

1 reference

17 August 2017

Yuta Fuyuno

16

1 reference

17 August 2017

Ramesh C Juyal

18

1 reference

17 August 2017

Garima Juyal

19

1 reference

17 August 2017

Timothy R Orchard

25

1 reference

17 August 2017

Homayon Vahedi

26

1 reference

17 August 2017

Ajit Sood

27

1 reference

17 August 2017

Joseph Y Sung

28

1 reference

17 August 2017

Keiko Yamazaki

31

1 reference

17 August 2017

International Multiple Sclerosis Genetics Consortium

33

1 reference

17 August 2017

International IBD Genetics Consortium

34

1 reference

17 August 2017

Miles Parkes

37

1 reference

17 August 2017

Thelma Bk

38

1 reference

17 August 2017

language of work or name

English

0 references

publication date

20 July 2015

1 reference

17 August 2017

1 reference

17 August 2017

47

1 reference

17 August 2017

9

1 reference

17 August 2017

979-986

1 reference

Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Mapping the genetic architecture of gene regulation in whole blood

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Oncostatin M mediates STAT3-dependent intestinal epithelial restitution via increased cell proliferation, decreased apoptosis and upregulation of SERPIN family members

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Genetics of rheumatoid arthritis contributes to biology and drug discovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Differential influences of the aryl hydrocarbon receptor on Th17 mediated responses in vitro and in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Systematic identification of trans eQTLs as putative drivers of known disease associations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

p40phox expression regulates neutrophil recruitment and function during the resolution phase of intestinal inflammation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

NFATc1/αA: The other Face of NFAT Factors in Lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Conditional ablation of CD205 conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

optiCall: a robust genotype-calling algorithm for rare, low-frequency and common variants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Genotype imputation with thousands of genomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Regulation of immune responses by prostaglandin E2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

A linear complexity phasing method for thousands of genomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

A user's guide to the encyclopedia of DNA elements (ENCODE)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

An Investigation of Genome-Wide Studies Reported Susceptibility Loci for Ulcerative Colitis Shows Limited Replication in North Indians

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Synthetic associations are unlikely to account for many common disease genome-wide association signals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Synthetic associations created by rare variants do not explain most GWAS results

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

IκBζ is essential for natural killer cell activation in response to IL-12 and IL-18.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Biological, clinical and population relevance of 95 loci for blood lipids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Evoker: a visualization tool for genotype intensity data

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Rare variants create synthetic genome-wide associations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

PLINK: a tool set for whole-genome association and population-based linkage analyses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Principal components analysis corrects for stratification in genome-wide association studies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Assessing the impact of population stratification on genetic association studies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Measuring inconsistency in meta-analyses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8 T cell tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Quantifying heterogeneity in a meta-analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Incidence and phenotype of inflammatory bowel disease based on results from the Asia-pacific Crohn's and colitis epidemiology study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

IκBζ is a transcriptional key regulator of CCL2/MCP-1.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Transethnic meta‐analysis of genomewide association studies

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Increased expression of CCL20 in human inflammatory bowel disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

CCR6 has a non‐redundant role in the development of inflammatory bowel disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4881818

HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26192919

12 December 2020

inferred from PubMed ID database lookup

IκBζ regulates TH17 development by cooperating with ROR nuclear receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26192919

12 December 2020

inferred from PubMed ID database lookup

Covariances of relatives stemming from a population undergoing mixed self and random mating

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26192919

12 December 2020

inferred from PubMed ID database lookup

Efficient computation with a linear mixed model on large-scale data sets with applications to genetic studies

1 reference

Crossref

https://api.crossref.org/works/10.1038/NG.3359

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NG.3359

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

26192919

1 reference