Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice (Q36929398)

17 August 2017

Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice (English)

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17 August 2017

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Eleftheria Maratos-Flier

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object named as

Eleftheria Maratos-Flier

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17 August 2017

Ying Dai

1

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17 August 2017

Tomas Kiselak

2

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17 August 2017

Joanne Clark

3

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17 August 2017

Elizabeth Clore

4

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17 August 2017

Kangni Zheng

5

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17 August 2017

Allen Cheng

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17 August 2017

Gregory C Kujoth

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17 August 2017

Tomas A Prolla

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17 August 2017

David K Simon

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17 August 2017

27 March 2013

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13

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4

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17 August 2017

282-291

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describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3682692/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's disease

29 September 2017

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Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice

29 September 2017

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Oral N-Acetyl-Cysteine Attenuates Loss of Dopaminergic Terminals in α-Synuclein Overexpressing Mice

29 September 2017

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Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice

29 September 2017

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Somatic mitochondrial DNA mutations in mammalian aging

29 September 2017

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Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis

29 September 2017

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Erythroid dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction

29 September 2017

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Neuroinflammation mediated by IL-1beta increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease

29 September 2017

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Morphometry of the human substantia nigra in ageing and Parkinson's disease

29 September 2017

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Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models

29 September 2017

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Leptin regulation of the mesoaccumbens dopamine pathway.

29 September 2017

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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

29 September 2017

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Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

29 September 2017

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Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

29 September 2017

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Premature ageing in mice expressing defective mitochondrial DNA polymerase

29 September 2017

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Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia

29 September 2017

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

29 September 2017

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

29 September 2017

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The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method

29 September 2017

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Ageing and Parkinson's disease: substantia nigra regional selectivity

29 September 2017

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Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice.

29 September 2017

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[11C]RTI-32 PET studies of the dopamine transporter in early dopa-naive Parkinson's disease: implications for the symptomatic threshold

27 June 2018

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What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men.

27 June 2018

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The clinical syndrome of striatal dopamine deficiency. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

27 June 2018

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Different rates of age-related loss for four murine monoaminergic neuronal populations

27 June 2018

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Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease

27 June 2018

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Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

27 June 2018

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Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum

27 June 2018

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Do Somatic Mitochondrial DNA Mutations Contribute to Parkinson's Disease?

27 June 2018

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Alpha-synuclein pathology and Parkinsonism associated with POLG1 mutations and multiple mitochondrial DNA deletions

4 September 2018

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Two novel POLG1 mutations in a patient with progressive external ophthalmoplegia, levodopa-responsive pseudo-orthostatic tremor and parkinsonism

4 September 2018

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Mitochondrial point mutations do not limit the natural lifespan of mice.

4 September 2018

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Does premature aging of the mtDNA mutator mouse prove that mtDNA mutations are involved in natural aging?

4 September 2018

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Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons

4 September 2018

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Somatic mitochondrial DNA mutations in single neurons and glia

4 September 2018

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Mice with MCH ablation resist diet-induced obesity through strain-specific mechanisms.

4 September 2018

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Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study.

4 September 2018

1 reference

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Unbiased morphometrical measurements show loss of pigmented nigral neurones with ageing

4 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682692

4 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682692

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682692

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682692

Role of the melanocortin-4 receptor in metabolic rate and food intake in mice

4 September 2018

1 reference

12 December 2020

Neuronal changes in the substantia nigra with aging: a Golgi study

1 reference

12 December 2020

Mutation of the linker region of the polymerase gamma-1 (POLG1) gene associated with progressive external ophthalmoplegia and Parkinsonism

1 reference

12 December 2020

Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases

1 reference

12 December 2020

Abnormalities of the electron transport chain in idiopathic Parkinson's disease

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12 December 2020

Mitochondrial complex I deficiency in Parkinson's disease

1 reference

12 December 2020

10.1016/J.MITO.2013.03.006

Identifiers

DOI

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

23542163

1 reference