High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence. (Q36905471)

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scientific article published on 21 March 2016

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English	High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence.	scientific article published on 21 March 2016

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30 March 2020

High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence (English)

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viral persistence

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Christopher Sundling

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John R. Mascola

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John R Mascola

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Richard T. Wyatt

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Richard T Wyatt

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Yimeng Wang

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Sijy O'Dell

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Kaifan Dai

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Jiang Zhu

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Yongli Xiao

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Gunilla B Karlsson Hedestam

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Yuxing Li

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30 March 2020

Journal of Immunology

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30 March 2020

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30 March 2020

3729-3743

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30 March 2020

HIV-1 gp140 epitope recognition is influenced by immunoglobulin DH gene segment sequence

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Antibody responses to envelope glycoproteins in HIV-1 infection

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Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design

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Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination

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Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization

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Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

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Antibodies in HIV-1 vaccine development and therapy

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IgBLAST: an immunoglobulin variable domain sequence analysis tool

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Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

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Isolation of antibody V(D)J sequences from single cell sorted rhesus macaque B cells.

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High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site

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Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVAC-HIV (vCP1521) and AIDSVAX B/E: a post-hoc analysis of the Thai phase 3 efficacy trial RV 144.

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Mechanism of Neutralization by the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01

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21 January 2018

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30 March 2020

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