Protein kinase C family: on the crossroads of cell signaling in skin and tumor epithelium (Q36895369)

16 August 2017

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title

Protein kinase C family: on the crossroads of cell signaling in skin and tumor epithelium (English)

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16 August 2017

Breitkreutz D

1

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16 August 2017

Braiman-Wiksman L

2

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16 August 2017

Daum N

3

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16 August 2017

Denning MF

4

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16 August 2017

Tennenbaum T

5

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16 August 2017

publication date

28 July 2007

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Journal of Cancer Research and Clinical Oncology

16 August 2017

published in

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16 August 2017

volume

133

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16 August 2017

issue

11

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16 August 2017

page(s)

793-808

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Phorbol 12-myristate 13-acetate-stimulated phosphorylation of erythrocyte membrane skeletal proteins is blocked by calpain inhibitors: possible role of protein kinase M.

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Activation of cutaneous protein kinase C alpha induces keratinocyte apoptosis and intraepidermal inflammation by independent signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

The eta isoform of protein kinase C is localized on rough endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Antagonistic effects of protein kinase C alpha and delta on both transformation and phospholipase D activity mediated by the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Phorbol ester-induced G1 arrest in BALB/MK-2 mouse keratinocytes is mediated by delta and eta isoforms of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Protein kinase C eta (PKC eta): its involvement in keratinocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Stimulation of the platelet-derived growth factor beta receptor signaling pathway activates protein kinase C-delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Tumor promotion by depleting cells of protein kinase C delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Protein kinase C involvement in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

The extended protein kinase C superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Comparison of epidermal protein kinase C activity, ornithine decarboxylase induction and DNA synthesis stimulated by TPA or dioctanoylglycerol in mouse strains with differing susceptibility to TPA-induced tumor promotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Induction of differentiation in normal human keratinocytes by adenovirus-mediated introduction of the eta and delta isoforms of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Three distinct mechanisms for translocation and activation of the delta subspecies of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Localization of Atypical Protein Kinase C Isoforms into Lysosome-Targeted Endosomes through Interaction with p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00432-007-0280-3

Suppression of apoptosis in the protein kinase Cdelta null mouse in vivo

21 January 2018

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12 December 2020

Protein kinase Cdelta mediates insulin-induced glucose transport in primary cultures of rat skeletal muscle

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12 December 2020

Protein kinase C-dependent down-regulation of basic fibroblast growth factor (FGF-2) receptor by phorbol ester and epidermal growth factor in porcine granulosa cells

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12 December 2020

Molecular cloning and characterization of PKC iota, an atypical isoform of protein kinase C derived from insulin-secreting cells

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12 December 2020

Molecular determinants of Akt-induced keratinocyte transformation

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12 December 2020

Activation of phorbol ester responsive form of protein kinase C zeta in association with Ca(2 )-induced differentiation of primary cultured mouse epidermal cells

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12 December 2020

Anchoring proteins for protein kinase C: a means for isozyme selectivity

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12 December 2020

Correlations between protein kinase C ζ signaling and morphological modifications during rat heart development and aging

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12 December 2020

Expression of protein kinase C isozymes in primary neuronal cultures of the rat cerebellum

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12 December 2020

Defects of basement membrane and hemidesmosome structure correlate with malignant phenotype and stromal interactions in HaCaT-Ras xenografts

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12 December 2020

The α and η Isoforms of Protein Kinase C Stimulate Transcription of Human Involucrin Gene

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12 December 2020

Protein kinase C epsilon subcellular localization domains and proteolytic degradation sites. A model for protein kinase C conformational changes

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12 December 2020

Proteolysis of protein kinase C: mM and μM calcium‐requiring calpains have different abilities to generate, and degrade the free catalytic subunit, protein kinase M

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12 December 2020

Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

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12 December 2020

Cholesterol sulfate, an activator of protein kinase C mediating squamous cell differentiation: a review

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12 December 2020

Epidermal keratinocytes: regulation of multiple cell phenotypes by multiple protein kinase C isoforms

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12 December 2020

Role of protein kinase C alpha in calcium induced keratinocyte differentiation: defective regulation in squamous cell carcinoma

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12 December 2020

Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes.

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12 December 2020

PKCdelta activation: a divergence point in the signaling of insulin and IGF-1-induced proliferation of skin keratinocytes

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12 December 2020

The cytoplasmic domain of alpha 6A integrin subunit is an in vitro substrate for protein kinase C

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12 December 2020

Protein kinase C epsilon, which sensitizes skin to sun's UV radiation-induced cutaneous damage and development of squamous cell carcinomas, associates with Stat3.

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12 December 2020

Structure/activity relationships of polyfunctional diterpenes of the tigliane type. A pharmacophore model for protein-kinase-C activators based on structure/activity studies and molecular modeling of the tumor promoters 12-O-tetradecanoylphorbol 13-

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12 December 2020

Activation of protein kinase C zeta induces serine phosphorylation of VAMP2 in the GLUT4 compartment and increases glucose transport in skeletal muscle

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12 December 2020

The V5 domain of protein kinase C plays a critical role in determining the isoform-specific localization, translocation, and biological function of protein kinase C-delta and -epsilon

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12 December 2020

Molecular mechanisms regulating protein kinase Czeta turnover and cellular transformation

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12 December 2020

Tight junctions and compositionally related junctional structures in mammalian stratified epithelia and cell cultures derived therefrom

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12 December 2020

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

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12 December 2020

Protein kinase C: structure, function, and regulation

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12 December 2020

Cholesterol sulfate, a second messenger for the eta isoform of protein kinase C, inhibits promotional phase in mouse skin carcinogenesis

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12 December 2020

The eta isoform of protein kinase C mediates transcriptional activation of the human transglutaminase 1 gene

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12 December 2020

Activation and nuclear translocation of PKCdelta, Pyk2 and ERK1/2 by gonadotropin releasing hormone in HEK293 cells

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12 December 2020

The role of protein kinase C in insulin action

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12 December 2020

Inhibition of tumor promoter 12-O-tetradecanoylphorbol-13-acetate-induced synthesis of epidermal ornithine decarboxylase messenger RNA and diacylglycerol-promoted mouse skin tumor formation by retinoic acid

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12 December 2020

Opposite roles of protein kinase C isoforms in proliferation, differentiation, apoptosis, and tumorigenicity of human HaCaT keratinocytes

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12 December 2020

PKC-δ is an apoptotic lamin kinase

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12 December 2020

UV-induced tyrosine phosphorylation of PKC delta and promotion of apoptosis in the HaCaT cell line

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12 December 2020

Caspase activation and disruption of mitochondrial membrane potential during UV radiation-induced apoptosis of human keratinocytes requires activation of protein kinase C.

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12 December 2020

aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization

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12 December 2020

The protein kinase C and protein kinase C related gene families.

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12 December 2020

The suprabasal expression of alpha 6 beta 4 integrin is associated with a high risk for malignant progression in mouse skin carcinogenesis.

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12 December 2020

The protein kinase C family: heterogeneity and its implications

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12 December 2020

Protein kinase C isoform delta is involved in the stimulation of the Na( )-H exchanger in C6 glioma cells.

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12 December 2020

PKCepsilon-mediated phosphorylation of vimentin controls integrin recycling and motility

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12 December 2020

Protein kinase C in normal human epidermal keratinocytes during proliferation and calcium-induced differentiation

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12 December 2020

Cell membrane associated protein kinase C as receptor of diterpene ester co-carcinogens of the tumor promoter type and the phenotypic expression of tumors

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12 December 2020

Protein kinase C and T cell activation

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12 December 2020

Protein kinase C isoforms in the epidermal tissues of normal and postburn human skin

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12 December 2020

In vivo regulation of protein kinase C by trans-phosphorylation followed by autophosphorylation

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12 December 2020

Insulin induces specific interaction between insulin receptor and protein kinase C delta in primary cultured skeletal muscle

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12 December 2020

The potential for isoenzyme‐selective modulation of protein kinase C

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12 December 2020

An important role for protein kinase C-delta in human keratinocyte migration on dermal collagen

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12 December 2020

Predominant expression of nPKC eta, a Ca(2 )-independent isoform of protein kinase C in epithelial tissues, in association with epithelial differentiation.

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12 December 2020

Association of protein kinase C activation with induction of ornithine decarboxylase in murine but not human keratinocyte cultures

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12 December 2020

TPA-enhanced motility and invasion in a highly metastatic variant (L-10) of human rectal adenocarcinoma cell line RCM-1: selective role of PKC-alpha and its inhibition by a combination of PDBu-induced PKC downregulation and antisense oligonucleotide

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12 December 2020

Loss of protein kinase C delta from human HaCaT keratinocytes upon ras transfection is mediated by TGF alpha

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12 December 2020

Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C

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12 December 2020

Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm

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12 December 2020

Differentiation specific functions in cultured and transplanted mouse keratinocytes: environmental influences on ultrastructure and keratin expression

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12 December 2020

Ligand structure-activity requirements and phospholipid dependence for the binding of phorbol esters to protein kinase D.

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12 December 2020

Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones

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12 December 2020

Transmembrane-4 superfamily proteins associate with activated protein kinase C (PKC) and link PKC to specific beta(1) integrins

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12 December 2020

Stimulation of protein kinase C during Ca(2 )-induced keratinocyte differentiation. Selective blockade of MARCKS phosphorylation by calmodulin

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12 December 2020

Discriminating expression of differentiation markers evolves in transplants of benign and malignant human skin keratinocytes through stromal interactions

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12 December 2020

Differential localization of conventional protein kinase C isoforms during mouse oocyte development

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12 December 2020

Protein kinase C epsilon signals ultraviolet light-induced cutaneous damage and development of squamous cell carcinoma possibly through Induction of specific cytokines in a paracrine mechanism

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12 December 2020

Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids

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12 December 2020

Caspase-3-mediated Cleavage of Protein Kinase C θ in Induction of Apoptosis

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12 December 2020

Protein kinase Cδ controls self-antigen-induced B-cell tolerance

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12 December 2020

Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion

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12 December 2020

Keratinocyte differentiation is associated with changes in the expression and regulation of phospholipase C isoenzymes

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12 December 2020

Tyrosine phosphorylation of protein kinase C-delta in response to its activation

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12 December 2020

Altered substrate selectivity of PKC-eta pseudosubstrate site mutants

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12 December 2020

A PKC-eta/Fyn-dependent pathway leading to keratinocyte growth arrest and differentiation

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12 December 2020

Molecular determinants of intrinsic resistance to doxorubicin in human cancer cell lines.

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12 December 2020

PKCeta enhances cell cycle progression, the expression of G1 cyclins and p21 in MCF-7 cells

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12 December 2020

Atypical protein kinase Cs are the Ras effectors that mediate repression of myogenic satellite cell differentiation

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12 December 2020

Protein kinase C-epsilon transgenic mice: a unique model for metastatic squamous cell carcinoma.

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12 December 2020

Getting under the skin of epidermal morphogenesis

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12 December 2020

A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin.

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12 December 2020

Protein kinase C binding partners

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12 December 2020

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

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12 December 2020

Identification of PKCzetaII: an endogenous inhibitor of cell polarity

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12 December 2020

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

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12 December 2020

PICK-1: a scaffold protein that interacts with Nectins and JAMs at cell junctions

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12 December 2020

Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins

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12 December 2020

Protein kinase C delta involvement in mammary tumor cell metastasis

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12 December 2020

Adaptor proteins in protein kinase C-mediated signal transduction

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12 December 2020

Genetic pathways required for epidermal morphogenesis

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12 December 2020

Immunological demonstration of a calcium-unresponsive protein kinase C of the delta-type in different species and murine tissues. Predominance in epidermis

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12 December 2020

Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.

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12 December 2020

The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis--thirty-third G. H. A. Clowes Memorial Award Lecture.

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12 December 2020

Staurosporine induces a sequential program of mouse keratinocyte terminal differentiation through activation of PKC isozymes

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12 December 2020

An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3

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12 December 2020

Multiple pathways control protein kinase C phosphorylation

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12 December 2020

Activation of protein kinase C by tyrosine phosphorylation in response to H 2 O 2

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12 December 2020

Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein

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12 December 2020

Differentiation-associated localization of nPKC eta, a Ca( )-independent protein kinase C, in normal human skin and skin diseases.

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12 December 2020

Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.

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12 December 2020

Tyrosine phosphorylation of specific protein kinase C isoenzymes participates in insulin stimulation of glucose transport in primary cultures of rat skeletal muscle

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12 December 2020

Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro

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12 December 2020

Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest

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12 December 2020

Transcripts encoding protein kinase C-alpha, -delta, -epsilon, -zeta, and -eta are expressed in basal and differentiating mouse keratinocytes in vitro and exhibit quantitative changes in neoplastic cells

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12 December 2020

Involvement of protein kinase C activation in ornithine decarboxylase gene expression in primary culture of newborn mouse epidermal cells and in skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate

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12 December 2020

Resistance of human leukemic cell lines to 1-beta-D-arabinofuranosylcytosine: characterization of an experimental model

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12 December 2020

Tyrosine phosphorylation is a mandatory proximal step in radiation-induced activation of the protein kinase C signaling pathway in human B-lymphocyte precursors.

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12 December 2020

Differential down-regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: association with epidermal hyperplasia and tumor promotion.

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12 December 2020

Differential translocation of protein kinase C epsilon during HeLa cell adhesion to a gelatin substratum

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12 December 2020

Deficiency of protein kinase Calpha in mice results in impairment of epidermal hyperplasia and enhancement of tumor formation in two-stage skin carcinogenesis

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12 December 2020

The Albert Lasker Medical Awards. The family of protein kinase C for signal transduction

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12 December 2020

Protein kinase Cdelta is activated by caspase-dependent proteolysis during ultraviolet radiation-induced apoptosis of human keratinocytes

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12 December 2020

Role of PI3K/Akt signaling in insulin-like growth factor-1 (IGF-1) skin tumor promotion

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12 December 2020

Phorbol esters modulate the turnover of both ether- and ester-linked phospholipids in cultured mammalian cells

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12 December 2020

Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity

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12 December 2020

The atypical protein kinase Cs. Functional specificity mediated by specific protein adapters

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12 December 2020

Syndecan-4 regulates localization, activity and stability of protein kinase C-alpha

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12 December 2020

Overexpression of protein kinase C-eta attenuates caspase activation and tumor necrosis factor-alpha-induced cell death

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12 December 2020

Spatiotemporal analysis of the molecular interaction between PICK1 and PKC

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12 December 2020

Involvement of protein kinase Cdelta in contact-dependent inhibition of growth in human and murine fibroblasts

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12 December 2020

Angiotensin II activates extracellular signal regulated kinases via protein kinase C and epidermal growth factor receptor in breast cancer cells.

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12 December 2020

Spectroscopic characterization of specific phorbol ester binding to PKC-receptor sites in membranes in situ

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12 December 2020

Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase

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12 December 2020

Differentiation of mouse keratinocytes is accompanied by PKC-dependent changes in AP-1 proteins

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12 December 2020

Lipid activators of protein kinase C.

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12 December 2020

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

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12 December 2020

Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans

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12 December 2020

Terminal differentiation of epidermal keratinocytes

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12 December 2020

PKCη associates with cyclin E/Cdk2 complex in serum-starved MCF-7 and NIH-3T3 cells

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12 December 2020

Protein kinase C delta

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12 December 2020

Tyrosine phosphorylation and stimulation of protein kinase C delta from porcine spleen by src in vitro. Dependence on the activated state of protein kinase C delta

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12 December 2020

Activated R-ras, Rac1, PI 3-kinase and PKCepsilon can each restore cell spreading inhibited by isolated integrin beta1 cytoplasmic domains

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12 December 2020

Structure and function of PICK1.

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12 December 2020

Signal integration and diversification through the p62 scaffold protein

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12 December 2020

Evidence for Involvement of Protein Kinase C (PKC)-ζ and Noninvolvement of Diacylglycerol-Sensitive PKCs in Insulin-Stimulated Glucose Transport in L6 Myotubes*

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12 December 2020

Differentiation of cultured human epidermal keratinocytes at high cell densities is mediated by endogenous activation of the protein kinase C signaling pathway.

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12 December 2020

Identification of PKC-isoform-specific biological actions using pharmacological approaches

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12 December 2020

Calcium-dependent involucrin expression is inversely regulated by protein kinase C (PKC)alpha and PKCdelta

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12 December 2020

Src family kinases phosphorylate protein kinase C delta on tyrosine residues and modify the neoplastic phenotype of skin keratinocytes

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12 December 2020

Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta.

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12 December 2020

Transgenic mice overexpressing protein kinase Cdelta in the epidermis are resistant to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate

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12 December 2020

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain

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12 December 2020

Protein kinase Cdelta-mediated phosphorylation of alpha6beta4 is associated with reduced integrin localization to the hemidesmosome and decreased keratinocyte attachment.

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12 December 2020

Protein kinase Cepsilon and development of squamous cell carcinoma, the nonmelanoma human skin cancer

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12 December 2020

Organotypic cocultures with genetically modified mouse fibroblasts as a tool to dissect molecular mechanisms regulating keratinocyte growth and differentiation.

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12 December 2020

Overexpression of protein kinase C-alpha in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-alpha expression but not tumor promotion.

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12 December 2020

Specific protein kinase C isozymes mediate the induction of keratinocyte differentiation markers by calcium.

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12 December 2020

Protein kinase C--a question of specificity

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12 December 2020

Complexities of the protein kinase C pathway

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12 December 2020

The protein kinase C family

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12 December 2020

Competitive inhibition by diacylglycerol of specific phorbol ester binding

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12 December 2020

Role of zeta PKC in B-cell signaling and function

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12 December 2020

Diacylglycerol is an effector of the clonal expansion of cells containing activated Ha-ras genes

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12 December 2020

Opposing activities of c-Fos and Fra-2 on AP-1 regulated transcriptional activity in mouse keratinocytes induced to differentiate by calcium and phorbol esters

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12 December 2020

Protein kinase C contains a pseudosubstrate prototope in its regulatory domain

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12 December 2020

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

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12 December 2020

High resolution immunogold analysis reveals distinct subcellular compartmentation of protein kinase Cγ and δ in rat Purkinje cells

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12 December 2020

Cross-talk between epidermal growth factor receptor and protein kinase C during calcium-induced differentiation of keratinocytes

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12 December 2020

Cholecystokinin-stimulated protein kinase C-delta kinase activation, tyrosine phosphorylation, and translocation are mediated by Src tyrosine kinases in pancreatic acinar cells

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12 December 2020

The role of protein kinase C in the regulation of cell growth and in signalling to the cell nucleus

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12 December 2020

Early epidermal destruction with subsequent epidermal hyperplasia is a unique feature of the papilloma-independent squamous cell carcinoma phenotype in PKCepsilon overexpressing transgenic mice

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12 December 2020

Differential regulation of alpha6beta4 integrin by PKC isoforms in murine skin keratinocytes

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12 December 2020

Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interaction

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12 December 2020

Protein kinase C: ports of anchor in the cell

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12 December 2020

Cholesterol sulfate activates multiple protein kinase C isoenzymes and induces granular cell differentiation in cultured murine keratinocytes.

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12 December 2020

Comparison of 12-O-tetradecanoylphorbol-13-acetate and teleocidin for induction of epidermal hyperplasia, activation of epidermal PKC isozymes and skin tumor promotion in SENCAR and C57BL/6 mice.

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12 December 2020

Characterization of protein kinase C theta activation loop autophosphorylation and the kinase domain catalytic mechanism

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12 December 2020

Development and initial characterization of several new inbred strains of SENCAR mice for studies of multistage skin carcinogenesis.

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12 December 2020

The proapoptotic tumor suppressor protein kinase C-delta is lost in human squamous cell carcinomas

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12 December 2020

Differential expression of protein kinase C isoenzymes in normal and psoriatic adult human skin: reduced expression of protein kinase C-beta II in psoriasis

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12 December 2020

Protein kinase C and other diacylglycerol effectors in cancer

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12 December 2020

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

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12 December 2020

Insulin receptor regulation of cell surface integrins: a possible mechanism contributing to the development of diabetic complications

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12 December 2020

Role of aPKC Isoforms and Their Binding Partners Par3 and Par6 in Epidermal Barrier Formation

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12 December 2020

Protein kinases C-beta and C-epsilon link the mast cell high-affinity receptor for IgE to the expression of c-fos and c-jun

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12 December 2020

Rottlerin induces a transformed phenotype in human keratinocytes

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12 December 2020

Protein kinase C and lipid signaling for sustained cellular responses

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12 December 2020

Limited proteolysis of protein kinase C subspecies by calcium-dependent neutral protease (calpain)

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12 December 2020

Relation of the induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C alpha, -delta and -epsilon transgenic mice

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12 December 2020

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12 December 2020

Lack of nidogen-1 and -2 prevents basement membrane assembly in skin-organotypic coculture

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12 December 2020

PKCeta associates with cyclin E/cdk2/p21 complex, phosphorylates p21 and inhibits cdk2 kinase in keratinocytes.

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12 December 2020

Altered expression and localization of PKC eta in human breast tumors

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12 December 2020

Inhibitory Properties of the Regulatory Domains of Human Protein Kinase Cα and Mouse Protein Kinase Cε

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12 December 2020

Differential modulation of epidermal keratinization in immortalized (HaCaT) and tumorigenic human skin keratinocytes (HaCaT-ras) by retinoic acid and extracellular Ca2 .

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12 December 2020

Protein kinase M zeta synthesis from a brain mRNA encoding an independent protein kinase C zeta catalytic domain. Implications for the molecular mechanism of memory

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12 December 2020

Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex

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12 December 2020

Disruption of protein kinase Ceta results in impairment of wound healing and enhancement of tumor formation in mouse skin carcinogenesis.

1 reference

12 December 2020

Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies

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12 December 2020

Elevated expression of secondary, but not early, responding genes to phorbol ester tumor promoters in papillomas and carcinomas of mouse skin

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12 December 2020

Protein kinase Cdelta-mediated signal to ornithine decarboxylase induction is independent of skin tumor suppression

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12 December 2020

Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins

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12 December 2020

Nuclear import of PKCdelta is required for apoptosis: identification of a novel nuclear import sequence

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12 December 2020

Activation of protein kinase C triggers irreversible cell cycle withdrawal in human keratinocytes

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12 December 2020

Tight junctions in the skin

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12 December 2020

Protein kinase C-epsilon is implicated in neurite outgrowth in differentiating human neuroblastoma cells

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12 December 2020

Further identification of protein kinase C isozymes in mouse epidermis

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12 December 2020

Subnuclear Localization of Protein Kinase C δ in Beta Cells

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12 December 2020

Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta

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12 December 2020

Transglutaminase function in epidermis

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12 December 2020

Constitutive association of c-N-Ras with c-Raf-1 and protein kinase C epsilon in latent signaling modules

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12 December 2020

Inflammation in epithelial skin tumours: old stories and new ideas

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12 December 2020

Novel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38 delta mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha

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12 December 2020

NF-kappaB activation by protein kinase C isoforms and B-cell function

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12 December 2020

Loss of protein kinase Calpha expression may enhance the tumorigenic potential of Gli1 in basal cell carcinoma

1 reference

12 December 2020

Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide

1 reference

12 December 2020

Cholesterol sulfate, a novel activator for the eta isoform of protein kinase C.

1 reference

12 December 2020

The regulation of skin proliferation and differentiation in the IR null mouse: implications for skin complications of diabetes

1 reference

12 December 2020

In vitro induction of human skin ornithine decarboxylase by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate

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12 December 2020

Isolation and characterization of human repetin, a member of the fused gene family of the epidermal differentiation complex

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12 December 2020

PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic

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12 December 2020

Protein kinase C delta overexpressing transgenic mice are resistant to chemically but not to UV radiation-induced development of squamous cell carcinomas: a possible link to specific cytokines and cyclooxygenase-2.

1 reference

12 December 2020

Phospholipase Cgamma/diacylglycerol-dependent activation of beta2-chimaerin restricts EGF-induced Rac signaling

1 reference

12 December 2020

10.1007/S00432-007-0280-3

Identifiers

DOI

1 reference

16 August 2017

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