Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer. (Q36870100)

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29 February 2020

title

Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer (English)

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29 February 2020

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1

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Monica Schiappacassi

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Sara Lovisa

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Marina Bagnoli

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Massimo Libra

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Sara D'Andrea

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Vincenzo Canzonieri

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Loredana Militello

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Marco Napoli

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29 February 2020

Giorgio Giorda

12

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29 February 2020

Delia Mezzanzanica

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Barbara Valeri

16

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Alfonso Colombatti

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29 February 2020

Barbara Belletti

19

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29 February 2020

Giannino Del Sal

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29 February 2020

Gustavo Baldassarre

21

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29 February 2020

Alessandra Dall'Acqua

4

object named as

Alessandra Dall'Acqua

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29 February 2020

author name string

Francesca Lovat

6

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29 February 2020

Barbara Pivetta

13

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29 February 2020

Mattia Barbareschi

15

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29 February 2020

Silvana Canevari

17

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publication date

22 April 2013

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29 February 2020

published in

EMBO Molecular Medicine

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volume

5

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29 February 2020

issue

5

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page(s)

707-722

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Stathmin is dispensable for tumor onset in mice

29 February 2020

cites work

1 reference

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The rebel angel: mutant p53 as the driving oncogene in breast cancer

29 September 2017

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Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations

29 September 2017

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Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop.

29 September 2017

1 reference

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Stathmin: a protein with many tasks. New biomarker and potential target in cancer

29 September 2017

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A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

29 September 2017

1 reference

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Integrated genomic analyses of ovarian carcinoma

29 September 2017

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Stathmin 1, a marker of PI3K pathway activation and regulator of microtubule dynamics, is expressed in early pelvic serous carcinomas.

29 September 2017

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Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm

29 September 2017

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Bub1 and BubR1: at the Interface between Chromosome Attachment and the Spindle Checkpoint

29 September 2017

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Centromeres: unique chromatin structures that drive chromosome segregation

29 September 2017

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29 September 2017

Global cancer statistics

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p53 and its mutants in tumor cell migration and invasion

29 September 2017

1 reference

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The role of mutant p53 in human cancer

29 September 2017

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A genomic and transcriptomic approach for a differential diagnosis between primary and secondary ovarian carcinomas in patients with a previous history of breast cancer

29 September 2017

1 reference

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Mutant p53 gain-of-function in cancer

29 September 2017

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Ovarian cancer pathogenesis: a model in evolution

29 September 2017

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Ovarian carcinoma pathology and genetics: recent advances

29 September 2017

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29 September 2017

Modes of p53 regulation

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A role of DNA-PK for the metabolic gene regulation in response to insulin

29 September 2017

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Activation of DNA-PK by ionizing radiation is mediated by protein phosphatase 6.

29 September 2017

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RCS1, a substrate of APC/C, controls the metaphase to anaphase transition

29 September 2017

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EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation.

29 September 2017

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Peptide aptamers targeting mutant p53 induce apoptosis in tumor cells

29 September 2017

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The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss

29 September 2017

1 reference

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Early events in the pathogenesis of epithelial ovarian cancer

29 September 2017

1 reference

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Protumorigenic overexpression of stathmin/Op18 by gain-of-function mutation in p53 in human hepatocarcinogenesis.

29 September 2017

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Reactivation of mutant p53: molecular mechanisms and therapeutic potential

29 September 2017

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Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1

29 September 2017

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Inhibition of hsp90 compromises the DNA damage response to radiation

29 September 2017

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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

29 September 2017

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p53: traffic cop at the crossroads of DNA repair and recombination

29 September 2017

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Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries

29 September 2017

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The role of stathmin in the regulation of the cell cycle

29 September 2017

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DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53.

29 September 2017

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The oncoprotein 18/stathmin family of microtubule destabilizers

29 September 2017

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Cell cycle-dependent expression and nucleolar localization of hCAP-H

29 September 2017

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A role for loss of p53 function in sensitivity of ovarian carcinoma cells to taxanes

29 September 2017

1 reference

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Regulation of p53 in response to DNA damage

29 September 2017

1 reference

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

29 September 2017

1 reference

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DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization

29 September 2017

1 reference

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An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control

29 September 2017

1 reference

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

29 September 2017

1 reference

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Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

29 September 2017

1 reference

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Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.

29 September 2017

1 reference

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p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3662314

p53 gene status and response to platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23610071

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phosphorylation of p53 serine 15 increases interaction with CBP

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23610071

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/EMMM.201201504

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23610071 AND SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23610071 AND SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

23610071

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23610071 AND SRC:MED&resulttype=core&format=json