IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity (Q36863144)

16 August 2017

IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity (English)

1 reference

16 August 2017

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Sathi Babu Chodisetti

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

Chetna Soni

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

Stephanie L Schell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

Melinda J Elias

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

Eric B Wong

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

Timothy K Cooper

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

Daisuke Kitamura

8

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3 June 2020

Ziaur S M Rahman

9

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3 June 2020

language of work or name

English

0 references

publication date

11 April 2016

1 reference

Journal of Experimental Medicine

16 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

volume

213

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

issue

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

715-732

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

Age-Associated B Cells: A T-bet-Dependent Effector with Roles in Protective and Pathogenic Immunity

3 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Blockade of interferon-γ normalizes interferon-regulated gene expression and serum CXCL10 levels in patients with systemic lupus erythematosus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

B cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Rationale for B cell targeting in SLE

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Interferon-γ and systemic autoimmunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

The unique features of follicular T cell subsets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Dual signaling by innate and adaptive immune receptors is required for TLR7-induced B-cell-mediated autoimmunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Impaired clearance of apoptotic cells in germinal centers: implications for loss of B cell tolerance and induction of autoimmunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Tolerogenic function of Blimp-1 in dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Germinal center B and follicular helper T cells: siblings, cousins or just good friends?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Development of self-reactive germinal center B cells and plasma cells in autoimmune Fc gammaRIIB-deficient mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Dysregulation of germinal centres in autoimmune disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody-forming cell and germinal center checkpoints

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

The evolution of human anti-double-stranded DNA autoantibodies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

T-bet regulates IgG class switching and pathogenic autoantibody production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Treatment of murine lupus with cDNA encoding IFN-gammaR/Fc

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

The role of somatic mutation in the pathogenic anti-DNA response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Rapid STAT phosphorylation via the B cell receptor. Modulatory role of CD19.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

IFN-gamma receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Critical role for Stat3 in T-dependent terminal differentiation of IgG B cells.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4 T cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Spontaneous formation of germinal centers in autoimmune mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Experimental therapy of systemic lupus erythematosus: the treatment of NZB/W mice with mouse soluble interferon-gamma receptor inhibits the onset of glomerulonephritis

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854731

Interferon-gamma gene polymorphisms associated with susceptibility to systemic lupus erythematosus

20 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084/JEM.20151722

Increased interferon-gamma (IFN-gamma), IL-10 and decreased IL-4 mRNA expression in peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE)

21 January 2018

1 reference

12 December 2020

Reciprocal regulation of polarized cytokine production by effector B and T cells

1 reference

12 December 2020

Activation of autoreactive B cells by CpG dsDNA

1 reference

12 December 2020

Inhibition of interferon regulatory factor-1 expression results in predominance of cell growth stimulatory effects of interferon-gamma due to phosphorylation of Stat1 and Stat3

1 reference

12 December 2020

IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice

1 reference

12 December 2020

Regulation of IFN-gamma production by B effector 1 cells: essential roles for T-bet and the IFN-gamma receptor

1 reference

12 December 2020

Stat1-dependent synergistic activation of T-bet for IgG2a production during early stage of B cell activation

1 reference

12 December 2020

FcgammaRIIB regulates autoreactive primary antibody-forming cell, but not germinal center B cell, activity

1 reference

12 December 2020

Activation of the STAT1 signalling pathway in lupus nephritis in MRL/lpr mice

1 reference

12 December 2020

STAT1 expression in dendritic cells, but not T cells, is required for immunity to Leishmania major

1 reference

12 December 2020

Excessive production of IFN-gamma in patients with systemic lupus erythematosus and its contribution to induction of B lymphocyte stimulator/B cell-activating factor/TNF ligand superfamily-13B

1 reference

12 December 2020

Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner

1 reference

12 December 2020

Interferon-γ excess leads to pathogenic accumulation of follicular helper T cells and germinal centers

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20151722

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27069112 AND SRC:MED&resulttype=core&format=json

3 June 2020

PubMed publication ID

27069112

1 reference