Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury (Q36853743)

16 August 2017

Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury (English)

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16 August 2017

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8

Evan Y Snyder

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16 August 2017

Yang D Teng

1

1 reference

16 August 2017

Howard Choi

2

1 reference

16 August 2017

Renna C Onario

3

1 reference

16 August 2017

Shan Zhu

4

1 reference

16 August 2017

Federico C Desilets

5

1 reference

16 August 2017

Shoumin Lan

6

1 reference

16 August 2017

Eric J Woodard

7

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16 August 2017

Marc E Eichler

9

1 reference

16 August 2017

Robert M Friedlander

10

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16 August 2017

language of work or name

English

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publication date

23 February 2004

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Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

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16 August 2017

101

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16 August 2017

9

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16 August 2017

3071-3076

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Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Recent advances in pathophysiology and treatment of spinal cord injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Miracles and molecules--progress in spinal cord repair

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

The role of steroids in acute spinal cord injury: an evidence-based analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Strategies for spinal cord injury repair.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Review of current evidence for apoptosis after spinal cord injury.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

A review of the neuropathology of human spinal cord injury with emphasis on special features

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Genetic approaches to neurotrauma research: opportunities and potential pitfalls of murine models.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Apoptosis after traumatic human spinal cord injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Mitochondria and apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Neuronal and glial apoptosis after traumatic spinal cord injury.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

A sensitive and reliable locomotor rating scale for open field testing in rats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Clinical pharmacokinetics of doxycycline and minocycline

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Activity of minocycline against Toxoplasma gondii infection in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Chapter 14 Descending motor pathways and the spinal motor system: Limbic and non-limbic components

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Experimental models for spinal cord injury research: physical and physiological considerations.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Local blockade of sodium channels by tetrodotoxin ameliorates tissue loss and long-term functional deficits resulting from experimental spinal cord injury.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Spinal cord contusion in the rat: behavioral analysis of functional neurologic impairment.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Correlative analyses of lesion development and functional status after graded spinal cord contusive injuries in the rat.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na channels and Na( )-Ca2 exchanger

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

The risk of neurologic damage with fractures of the vertebrae

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Pathology of experimental spinal cord trauma. II. Ultrastructure of axons and myelin

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Pathology of experimental spinal cord trauma. I. The necrotic lesion as a function of vascular injury.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

TIGR is upregulated in the chronic glial scar in response to central nervous system injury and inhibits neurite outgrowth

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Effect of minocycline in experimental autoimmune encephalomyelitis

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Temporal and segmental distribution of constitutive and inducible nitric oxide synthases after traumatic spinal cord injury: effect of aminoguanidine treatment

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Astrocytes and oligodendrocytes reactions after a total section of the rat spinal cord

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365746

A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0306239101

Basic fibroblast growth factor increases long-term survival of spinal motor neurons and improves respiratory function after experimental spinal cord injury

21 January 2018

1 reference

12 December 2020

Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury

1 reference

12 December 2020

Objective clinical assessment of motor function after experimental spinal cord injury in the rat

1 reference

12 December 2020

Epidemiology of spinal cord injury

1 reference

12 December 2020

Ineffectiveness of enzyme therapy on regeneration in the transected spinal cord of the rat

1 reference

12 December 2020

1 reference

12 December 2020

Cellular morphology of chronic spinal cord injury in the cat: analysis of myelinated axons by line-sampling

1 reference

12 December 2020

Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys

1 reference

12 December 2020

Basic and acidic fibroblast growth factors protect spinal motor neurones in vivo after experimental spinal cord injury

1 reference

12 December 2020

Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0306239101

1 reference

16 August 2017

0 references

1 reference

16 August 2017

PubMed publication ID

14981254

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