Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment. (Q36853502)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590911 AND SRC:MED&resulttype=core&format=json

1 March 2020

title

Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590911 AND SRC:MED&resulttype=core&format=json

1 March 2020

main subject

Alzheimer's disease

0 references

cognitive dysfunction

1 reference

1

1 reference

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1 March 2020

Willard M. Freeman

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590911 AND SRC:MED&resulttype=core&format=json

1 March 2020

William E. Sonntag

series ordinal

5

1 reference

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1 March 2020

3

Zoltan Ungvari

1 reference

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1 March 2020

author name string

Anna Csiszar

series ordinal

4

1 reference

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1 March 2020

language of work or name

English

0 references

publication date

20 November 2015

1 reference

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The Journals of Gerontology

1 March 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590911 AND SRC:MED&resulttype=core&format=json

1 March 2020

volume

71

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1 March 2020

issue

1

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1 March 2020

page(s)

13-20

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Phase 3 solanezumab trials: Secondary outcomes in mild Alzheimer's disease patients

1 March 2020

cites work

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Intranasal Insulin Improves Age-Related Cognitive Deficits and Reverses Electrophysiological Correlates of Brain Aging

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Higher rates of decline for women and apolipoprotein E epsilon4 carriers

29 September 2017

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29 September 2017

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29 September 2017

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Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells

29 September 2017

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A novel functional low-density lipoprotein receptor-related protein 6 gene alternative splice variant is associated with Alzheimer's disease.

29 September 2017

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Genome-wide methylation profiles reveal quantitative views of human aging rates

29 September 2017

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The role of DNA methylation in aging, rejuvenation, and age-related disease

29 September 2017

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29 September 2017

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29 September 2017

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The role of peripheral inflammatory markers in dementia and Alzheimer's disease: a meta-analysis

29 September 2017

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Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells.

29 September 2017

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A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.

29 September 2017

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29 September 2017

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Neurovascular defects and faulty amyloid-β vascular clearance in Alzheimer's disease

29 September 2017

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Memory enhancement and deep-brain stimulation of the entorhinal area.

29 September 2017

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Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging

29 September 2017

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Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial

29 September 2017

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The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

29 September 2017

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Neurovascular coupling is impaired in slow walkers: the MOBILIZE Boston Study.

29 September 2017

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Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

29 September 2017

1 reference

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Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease

29 September 2017

1 reference

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Anti-Aβ Therapeutics in Alzheimer's Disease: The Need for a Paradigm Shift

29 September 2017

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Activation and effective connectivity changes following explicit-memory training for face-name pairs in patients with mild cognitive impairment: a pilot study

29 September 2017

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Sex and age differences in atrophic rates: an ADNI study with n=1368 MRI scans

29 September 2017

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Mechanisms of vascular aging: new perspectives.

29 September 2017

1 reference

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Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions

29 September 2017

1 reference

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Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo

29 September 2017

1 reference

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Safety, tolerability, pharmacokinetics, and Abeta levels after short-term administration of R-flurbiprofen in healthy elderly individuals

29 September 2017

1 reference

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Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease

29 September 2017

1 reference

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Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain

29 September 2017

1 reference

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Imaging and CSF studies in the preclinical diagnosis of Alzheimer's disease.

29 September 2017

1 reference

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Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Microvascular plasticity in aging.

29 September 2017

1 reference

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The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Hypertension Induces Brain β-Amyloid Accumulation, Cognitive Impairment, and Memory Deterioration Through Activation of Receptor for Advanced Glycation End Products in Brain Vasculature

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Oxidative Stress Is a Central Target for Physical Exercise Neuroprotection Against Pathological Brain Aging

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Brain and cerebrovascular aging--new mechanisms and insights.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Aging, brain, and mobility: progresses and opportunities

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Blockage of GSK3β-mediated Drp1 phosphorylation provides neuroprotection in neuronal and mouse models of Alzheimer's disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Moderate-intensity physical activity, hippocampal volume, and memory in older adults with mild cognitive impairment

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Differentiating the Influences of Aging and Adiposity on Brain Weights, Levels of Serum and Brain Cytokines, Gastrointestinal Hormones, and Amyloid Precursor Protein

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Regional cerebral glucose metabolism and gait speed in healthy community-dwelling older women

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

The neural basis of age-related changes in motor imagery of gait: an fMRI study.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Regulatory innovation and drug development for early-stage Alzheimer's disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Occipital cortex activation studied with simultaneous recordings of functional transcranial Doppler ultrasound (fTCD) and visual evoked potential (VEP) in cognitively normal human subjects: effect of healthy aging

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in Alzheimer disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Lifetime risk of dementia and Alzheimer's disease. The impact of mortality on risk estimates in the Framingham Study

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4851715

Synapses and Alzheimer's disease

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093/GERONA/GLV206

Neurodegeneration and the neurovascular unit

21 January 2018

1 reference

12 December 2020

Effects of moderate caloric restriction on cortical microvascular density and local cerebral blood flow in aged rats

1 reference

12 December 2020

1 reference

12 December 2020

A mass spectrometric approach for characterization of amyloid-β aggregates and identification of their post-translational modifications

1 reference

12 December 2020

Identifiers

DOI

10.1093/GERONA/GLV206

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590911 AND SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590911 AND SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

26590911

1 reference