mTOR inhibitors are synergistic with methotrexate: an effective combination to treat acute lymphoblastic leukemia. (Q36843792)

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title

mTOR inhibitors are synergistic with methotrexate: an effective combination to treat acute lymphoblastic leukemia (English)

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1 reference

7

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Alix E Seif

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12

Stephan A Grupp

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author name string

David T Teachey

1

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Cecilia Sheen

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Junior Hall

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Theresa Ryan

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Valerie I Brown

5

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Jonathan Fish

6

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Robin Norris

9

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Yueh J Chang

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Martin Carroll

11

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language of work or name

English

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publication date

10 June 2008

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volume

112

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issue

5

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page(s)

2020-2023

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The molecular mechanism of resistance to methotrexate in mouse methotrexate-resistant cells by cancer drug resistance and metabolism SuperArray

8 January 2020

cites work

1 reference

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Mammalian target of rapamycin as a therapeutic target in leukemia

29 September 2017

1 reference

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The mTOR inhibitor CCI-779 induces apoptosis and inhibits growth in preclinical models of primary adult human ALL

29 September 2017

1 reference

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Prognosis in childhood and adult acute lymphoblastic leukaemia: a question of maturation?

29 September 2017

1 reference

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Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells

29 September 2017

1 reference

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Rapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling

29 September 2017

1 reference

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Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518903

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518903

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518903

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518903

10.1182/BLOOD-2008-02-137141

29 September 2017

Identifiers

DOI

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8 January 2020

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8 January 2020

PubMed publication ID

18544682

1 reference