The pilocarpine model of temporal lobe epilepsy (Q36841686)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550176 AND SRC:MED&resulttype=core&format=json

8 January 2020

review article

3 references

22 June 2022

26 October 2022

The pilocarpine model of temporal lobe epilepsy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550176 AND SRC:MED&resulttype=core&format=json

8 January 2020

main subject

temporal lobe epilepsy

1 reference

12 September 2019

1 reference

12 September 2019

1 reference

12 September 2019

1 reference

PubMed publication ID

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550176 AND SRC:MED&resulttype=core&format=json

8 January 2020

Giuseppe Biagini

series ordinal

3

1 reference

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8 January 2020

5

Massimo Avoli

1 reference

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8 January 2020

author name string

Daniela Longo

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550176 AND SRC:MED&resulttype=core&format=json

8 January 2020

Roland S G Jones

series ordinal

4

1 reference

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8 January 2020

language of work or name

1 reference

26 April 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550176 AND SRC:MED&resulttype=core&format=json

Journal of Neuroscience Methods

8 January 2020

30 July 2008

2 references

22 June 2022

26 October 2022

8 references

14 March 2019

19 March 2019

25 April 2019

24 June 2019

12 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550176 AND SRC:MED&resulttype=core&format=json

8 January 2020

22 June 2022

26 October 2022

172

1 reference

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8 January 2020

issue

2

1 reference

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8 January 2020

page(s)

143-157

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550176 AND SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

8 January 2020

copyright license

7 references

14 March 2019

19 March 2019

25 April 2019

24 June 2019

12 September 2019

22 June 2022

on focus list of Wikimedia project

26 October 2022

copyright status

copyrighted

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ScienceSource

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cites work

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Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy

29 September 2017

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When should temporal-lobe epilepsy be treated surgically?

29 September 2017

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New insights from the use of pilocarpine and kainate models.

29 September 2017

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Spontaneous recurrent seizures and neuropathology in the chronic phase of the pilocarpine and picrotoxin model epilepsy

29 September 2017

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Social regulation of the cortisol levels in early human development

29 September 2017

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Survival of dentate hilar mossy cells after pilocarpine-induced seizures and their synchronized burst discharges with area CA3 pyramidal cells

29 September 2017

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29 September 2017

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Relationship between neuronal loss and interictal glucose metabolism during the chronic phase of the lithium-pilocarpine model of epilepsy in the immature and adult rat.

29 September 2017

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29 September 2017

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Differential progression of Dark Neuron and Fluoro-Jade labelling in the rat hippocampus following pilocarpine-induced status epilepticus

29 September 2017

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Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice

29 September 2017

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NMDA receptor‐mediated pilocarpine‐induced seizures: characterization in freely moving rats by microdialysis

29 September 2017

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29 September 2017

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Quantitative evaluation of neuronal loss in the dorsal hippocampus in rats with long-term pilocarpine seizures

29 September 2017

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29 September 2017

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29 September 2017

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Ontogenic study of lithium-pilocarpine-induced status epilepticus in rats

29 September 2017

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Proepileptic influence of a focal vascular lesion affecting entorhinal cortex-CA3 connections after status epilepticus

29 September 2017

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Depression of glutamate and GABA release by presynaptic GABAB receptors in the entorhinal cortex in normal and chronically epileptic rats.

27 June 2018

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A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsy

27 June 2018

1 reference

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Brain-derived neurotrophic factor superinduction parallels anti-epileptic--neuroprotective treatment in the pilocarpine epilepsy model

27 June 2018

1 reference

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Hormonal and gestational parameters in female rats submitted to the pilocarpine model of epilepsy

27 June 2018

1 reference

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Lithium-pilocarpine status epilepticus in the immature rabbit

27 June 2018

1 reference

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Human fascia dentata anatomy and hippocampal neuron densities differ depending on the epileptic syndrome and age at first seizure

27 June 2018

1 reference

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Metyrapone, an inhibitor of glucocorticoid production, reduces brain injury induced by focal and global ischemia and seizures

27 June 2018

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The pilocarpine model of epilepsy in mice

27 June 2018

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Paradoxical facilitation of pilocarpine-induced seizures in the mouse by MK-801 and the nitric oxide synthesis inhibitor L-NAME.

27 June 2018

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Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats

27 June 2018

1 reference

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Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats

27 June 2018

1 reference

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Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study

27 June 2018

1 reference

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Seizures produced by pilocarpine in mice: a behavioral, electroencephalographic and morphological analysis

27 June 2018

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Systemic Cholinergic Agents Induce Seizures and Brain Damage in Lithium-Treated Rats

27 June 2018

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Cholinomimetics produce seizures and brain damage in rats

27 June 2018

1 reference

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Characterization of lithium potentiation of pilocarpine-induced status epilepticus in rats

27 June 2018

1 reference

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Effects of drugs on the initiation and maintenance of status epilepticus induced by administration of pilocarpine to lithium-pretreated rats

27 June 2018

1 reference

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The susceptibility of rats to pilocarpine-induced seizures is age-dependent

27 June 2018

1 reference

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The functional anatomy and pathology of lithium-pilocarpine and high-dose pilocarpine seizures

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Susceptibility to pilocarpine-induced seizures in rats increases with age.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

On the relevance of prolonged convulsive status epilepticus in animals to the etiology and neurobiology of human temporal lobe epilepsy

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Drug resistance and hippocampal damage after delayed treatment of pilocarpine-induced epilepsy in the rat.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Differential paired-pulse responses between the CA1 region and the dentate gyrus are related to altered CLC-2 immunoreactivity in the pilocarpine-induced rat epilepsy model

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Subiculum network excitability is increased in a rodent model of temporal lobe epilepsy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Gray matter atrophy associated with duration of temporal lobe epilepsy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Endogenous neurosteroids modulate epileptogenesis in a model of temporal lobe epilepsy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Hyperexcitability, interneurons, and loss of GABAergic synapses in entorhinal cortex in a model of temporal lobe epilepsy.

5 September 2018

1 reference

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Impaired activation of CA3 pyramidal neurons in the epileptic hippocampus

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Effect of neonatal isolation on outcome following neonatal seizures in rats--the role of corticosterone

5 September 2018

1 reference

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Antiepileptic drug-resistant rats differ from drug-responsive rats in hippocampal neurodegeneration and GABA(A) receptor ligand binding in a model of temporal lobe epilepsy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Entorhinal cortex entrains epileptiform activity in CA1 in pilocarpine-treated rats.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Outcome of status epilepticus in immature rats varies according to the paraldehyde treatment.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Disruption of cortical development as a consequence of repetitive pilocarpine-induced status epilepticus in rats

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Entorhinal cortex involvement in human mesial temporal lobe epilepsy: an electrophysiologic and volumetric study

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Neocortical and hippocampal changes after multiple pilocarpine-induced status epilepticus in rats.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Cellular and network properties of the subiculum in the pilocarpine model of temporal lobe epilepsy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Expression analysis of metabotropic glutamate receptors I and III in mouse strains with different susceptibility to experimental temporal lobe epilepsy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

ILAE Commission Report. Mesial temporal lobe epilepsy with hippocampal sclerosis.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Absence-like seizures in adult rats following pilocarpine-induced status epilepticus early in life

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Perforant path activation of ectopic granule cells that are born after pilocarpine-induced seizures

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Reduced inhibition and increased output of layer II neurons in the medial entorhinal cortex in a model of temporal lobe epilepsy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Estradiol reduces seizure-induced hippocampal injury in ovariectomized female but not in male rats

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Hippocampal sclerosis is a progressive disorder: a longitudinal volumetric MRI study

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Reassessment of the effects of cycloheximide on mossy fiber sprouting and epileptogenesis in the pilocarpine model of temporal lobe epilepsy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Pilocarpine-induced epileptogenesis in the rat: impact of initial duration of status epilepticus on electrophysiological and neuropathological alterations

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Pilocarpine-induced seizure-like activity with increased BNDF and neuropeptide Y expression in organotypic hippocampal slice cultures

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Characterization of pharmacoresistance to benzodiazepines in the rat Li-pilocarpine model of status epilepticus

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Alterations of the neocortical GABAergic system in the pilocarpine model of temporal lobe epilepsy: neuronal damage and immunocytochemical changes in chronic epileptic rats

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Relations between brain pathology and temporal lobe epilepsy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Electrophysiologic abnormalities of the hippocampus in the pilocarpine/cycloheximide model of chronic spontaneous seizures

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Damage, reorganization, and abnormal neocortical hyperexcitability in the pilocarpine model of temporal lobe epilepsy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Short-term effects of pilocarpine on rat hippocampal neurons in culture

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Behavioral, morphologic, and electroencephalographic evaluation of seizures induced by intrahippocampal microinjection of pilocarpine

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Sex differences in models of temporal lobe epilepsy: role of testosterone

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Castration in female rats modifies the development of the pilocarpine model of epilepsy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Pilocarpine-induced status epilepticus results in mossy fiber sprouting and spontaneous seizures in C57BL/6 and CD-1 mice

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Fluorescent tracer in pilocarpine-treated rats shows widespread aberrant hippocampal neuronal connectivity.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Repeated low-dose treatment of rats with pilocarpine: low mortality but high proportion of rats developing epilepsy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Interstrain differences in cognitive functions in rats in relation to status epilepticus

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Newly formed excitatory pathways provide a substrate for hyperexcitability in experimental temporal lobe epilepsy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Lithium-pilocarpine-induced status epilepticus produces necrotic neurons with internucleosomal DNA fragmentation in adult rats

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Stress and the developing limbic-hypothalamic-pituitary-adrenal axis.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Cholinergic induction of network oscillations at 40 Hz in the hippocampus in vitro

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Status epilepticus induced by pilocarpine and picrotoxin

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Spontaneous seizures preferentially injure interneurons in the pilocarpine model of chronic spontaneous seizures

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Developmental aspects of the pilocarpine model of epilepsy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

The temporal evolution of neuronal damage from pilocarpine-induced status epilepticus

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

MK-801 sensitizes rats to pilocarpine induced limbic seizures and status epilepticus.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Long-term behavioral deficits following pilocarpine seizures in immature rats.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Progression in temporal lobe epilepsy: differential atrophy in mesial temporal structures

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Epileptiform activity induced by pilocarpine in the rat hippocampal-entorhinal slice preparation

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518220

Mossy fiber sprouting induced by repeated electroconvulsive shock seizures

20 October 2018

1 reference

12 December 2020

Carbachol induces fast oscillations in the medial but not in the lateral entorhinal cortex of the isolated guinea pig brain

1 reference

12 December 2020

Epileptogenesis in immature rats following recurrent status epilepticus

1 reference

12 December 2020

Temporal profile of neuronal injury following pilocarpine or kainic acid-induced status epilepticus

1 reference

12 December 2020

Blockade of pilocarpine- or kainate-induced mossy fiber sprouting by cycloheximide does not prevent subsequent epileptogenesis in rats

1 reference

12 December 2020

Preferential neuronal loss in layer III of the medial entorhinal cortex in rat models of temporal lobe epilepsy

1 reference

12 December 2020

The course of untreated seizures in the pilocarpine model of epilepsy

1 reference

12 December 2020

Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat

1 reference

12 December 2020

1 reference

12 December 2020

10.1016/J.JNEUMETH.2008.04.019

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550176 AND SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550176 AND SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

18550176

1 reference