The multidrug resistance pump ABCB1 is a substrate for the ubiquitin ligase NEDD4-1 (Q36835064)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26006083 AND SRC:MED&resulttype=core&format=json

15 February 2020

title

The multidrug resistance pump ABCB1 is a substrate for the ubiquitin ligase NEDD4-1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26006083 AND SRC:MED&resulttype=core&format=json

NEDD4 E3 ubiquitin protein ligase

15 February 2020

main subject

multiple drug resistance

1 reference

based on heuristic

inferred from title

1 reference

ATP binding cassette subfamily B member 1

GOA release 2020-03-11

1 reference

ubiquitin protein ligase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

James A. Sullivan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26006083 AND SRC:MED&resulttype=core&format=json

15 February 2020

author name string

Begum G Akkaya

1

1 reference

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15 February 2020

Joseph K Zolnerciks

2

1 reference

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15 February 2020

Tasha K Ritchie

3

1 reference

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15 February 2020

Bjoern Bauer

4

1 reference

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15 February 2020

Anika M S Hartz

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26006083 AND SRC:MED&resulttype=core&format=json

15 February 2020

Kenneth J Linton

7

1 reference

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15 February 2020

publication date

26 May 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26006083 AND SRC:MED&resulttype=core&format=json

Molecular Membrane Biology

15 February 2020

published in

1 reference

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15 February 2020

volume

32

1 reference

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15 February 2020

issue

2

1 reference

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15 February 2020

page(s)

39-45

1 reference

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FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin--proteasome pathway in cancer cells.

15 February 2020

cites work

1 reference

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Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease

29 September 2017

1 reference

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Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscs

29 September 2017

1 reference

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Physiological functions of the HECT family of ubiquitin ligases

29 September 2017

1 reference

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Suppression of amyloid deposition leads to long-term reductions in Alzheimer's pathologies in Tg2576 mice

29 September 2017

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Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

29 September 2017

1 reference

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The blood-brain barrier in health and chronic neurodegenerative disorders

29 September 2017

1 reference

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Evidence for a Sav1866-like architecture for the human multidrug transporter P-glycoprotein

29 September 2017

1 reference

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Actin disruption inhibits endosomal traffic of P-glycoprotein-EGFP and resistance to daunorubicin accumulation

29 September 2017

1 reference

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LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

29 September 2017

1 reference

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The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844833

Detailed characterization of cysteine-less P-glycoprotein reveals subtle pharmacological differences in function from wild-type protein

29 September 2017

1 reference

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NeW wrinkles for an old domain

29 September 2017

1 reference

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Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking

29 September 2017

1 reference

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Human ubiquitin-protein ligase Nedd4: expression, subcellular localization and selective interaction with ubiquitin-conjugating enzymes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844833

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

29 September 2017

1 reference

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Characterization of a novel protein-binding module--the WW domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844833

P-glycoprotein stability is affected by serum deprivation and high cell density in multidrug-resistant cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844833

The Q loops of the human multidrug resistance transporter ABCB1 are necessary to couple drug binding to the ATP catalytic cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4844833

Cd36, a class B scavenger receptor, functions as a monomer to bind acetylated and oxidized low-density lipoproteins

27 June 2018

1 reference

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Multiple interactions drive adaptor-mediated recruitment of the ubiquitin ligase rsp5 to membrane proteins in vivo and in vitro.

27 June 2018

1 reference

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P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model

27 June 2018

1 reference

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Stability and covalent modification of P-glycoprotein in multidrug-resistant KB cells

27 June 2018

1 reference

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Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents.

27 June 2018

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27 June 2018

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An investigation into the role of P-glycoprotein in Alzheimer's disease lesion pathogenesis

5 September 2018

1 reference

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MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier

5 September 2018

1 reference

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Regulation of the stability of P-glycoprotein by ubiquitination

5 September 2018

1 reference

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Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans

5 September 2018

1 reference

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Biosynthesis, processing and half-life of P-glycoprotein in a human multidrug-resistant KB cell

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26006083

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3109/09687688.2015.1023378

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26006083 AND SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26006083 AND SRC:MED&resulttype=core&format=json

15 February 2020

PubMed publication ID

26006083

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26006083 AND SRC:MED&resulttype=core&format=json