Manipulating the chemokine-chemokine receptor network to treat cancer (Q36822184)

16 August 2017

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title

Manipulating the chemokine-chemokine receptor network to treat cancer (English)

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16 August 2017

4

Kadri Altundag

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16 August 2017

Pier A Ruffini

1

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16 August 2017

Paolo Morandi

series ordinal

2

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16 August 2017

Neslihan Cabioglu

series ordinal

3

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16 August 2017

Massimo Cristofanilli

series ordinal

5

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16 August 2017

language of work or name

English

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publication date

1 June 2007

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16 August 2017

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16 August 2017

volume

109

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16 August 2017

issue

12

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16 August 2017

page(s)

2392-2404

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Intralesional injection of adenovirus encoding CC chemokine ligand 16 inhibits mammary tumor growth and prevents metastatic-induced death after surgical removal of the treated primary tumor

16 August 2017

cites work

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The CC chemokine CK beta-11/MIP-3 beta/ELC/Exodus 3 mediates tumor rejection of murine breast cancer cells through NK cells

21 January 2018

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Antitumor effects of the mouse chemokine 6Ckine/SLC through angiostatic and immunological mechanisms

21 January 2018

1 reference

Secondary lymphoid tissue chemokine mediates T cell-dependent antitumor responses in vivo

21 January 2018

1 reference

Intratumoral coinjection of two adenoviruses, one encoding the chemokine IFN-gamma-inducible protein-10 and another encoding IL-12, results in marked antitumoral synergy

21 January 2018

1 reference

MIP-3alpha transfection into a rodent tumor cell line increases intratumoral dendritic cell infiltration but enhances (facilitates) tumor growth and decreases immunogenicity

21 January 2018

1 reference

Cutaneous injection of human subjects with macrophage inflammatory protein-1 alpha induces significant recruitment of neutrophils and monocytes

21 January 2018

1 reference

Chemokines: a new classification system and their role in immunity

21 January 2018

1 reference

7 January 2021

Chemokines: multiple levels of leukocyte migration control.

1 reference

7 January 2021

The immune system. First of two parts

1 reference

7 January 2021

Chemokines: more than just road signs

1 reference

7 January 2021

Cancer and the chemokine network

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7 January 2021

Involvement of chemokine receptors in breast cancer metastasis

1 reference

7 January 2021

Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells

1 reference

7 January 2021

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.

1 reference

7 January 2021

Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis

1 reference

7 January 2021

CXCR4/CXCL12 expression and signalling in kidney cancer

1 reference

7 January 2021

Stromal cell-derived factor-1alpha promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities.

1 reference

7 January 2021

A possible role for CXCR4 and its ligand, the CXC chemokine stromal cell-derived factor-1, in the development of bone marrow metastases in neuroblastoma

1 reference

7 January 2021

CCR7 and CXCR4 as novel biomarkers predicting axillary lymph node metastasis in T1 breast cancer

1 reference

7 January 2021

Expression of chemokine receptors predicts the site of metastatic relapse in patients with axillary node positive primary breast cancer

1 reference

7 January 2021

The elevated level of CXCR4 is correlated with nodal metastasis of human breast cancer

1 reference

7 January 2021

Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma

1 reference

7 January 2021

Expression of CXCR4 is associated with axillary lymph node status in patients with early breast cancer

1 reference

7 January 2021

Possible role of stromal-cell-derived factor-1/CXCR4 signaling on lymph node metastasis of oral squamous cell carcinoma

1 reference

7 January 2021

Effect of chemokine receptors CXCR4 and CCR7 on the metastatic behavior of human colorectal cancer.

1 reference

7 January 2021

Tumor-cell homing to lymph nodes and bone marrow and CXCR4 expression in esophageal cancer

1 reference

7 January 2021

Chemokine receptor CXCR4 and early-stage non-small cell lung cancer: pattern of expression and correlation with outcome

1 reference

7 January 2021

Overexpression of CCR7 mRNA in nonsmall cell lung cancer: correlation with lymph node metastasis

1 reference

7 January 2021

The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases

1 reference

7 January 2021

Human melanoma metastases express functional CXCR4.

1 reference

7 January 2021

Messenger RNA expression levels of CXCR4 correlate with metastatic behavior and outcome in patients with osteosarcoma

1 reference

7 January 2021

Expression of chemokine CXCL12 and its receptor CXCR4 in human epithelial ovarian cancer: an independent prognostic factor for tumor progression

1 reference

7 January 2021

Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival.

1 reference

7 January 2021

The expression of functional chemokine receptor CXCR4 is associated with the metastatic potential of human nasopharyngeal carcinoma

1 reference

7 January 2021

Expression of CXCR4 Predicts Poor Prognosis in Patients with Malignant Melanoma

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7 January 2021

The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study.

1 reference

7 January 2021

Molecular characterization of the tumor microenvironment in breast cancer

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7 January 2021

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

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7 January 2021

Regulation of the chemokine receptor CXCR4 by hypoxia

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7 January 2021

Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

1 reference

7 January 2021

Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor

1 reference

7 January 2021

Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis

1 reference

7 January 2021

Roots and stems: stem cells in cancer.

1 reference

7 January 2021

CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells

1 reference

7 January 2021

Expression of CC chemokine receptor-7 and regional lymph node metastasis of B16 murine melanoma

1 reference

7 January 2021

Prediction of lymph node metastasis in colorectal carcinoma by expressionof chemokine receptor CCR7

1 reference

7 January 2021

CCL21 chemokine regulates chemokine receptor CCR7 bearing malignant melanoma cells.

1 reference

7 January 2021

Critical update and emerging trends in epidermal growth factor receptor targeting in cancer

1 reference

7 January 2021

Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.

1 reference

7 January 2021

CXCL-12/stromal cell-derived factor-1alpha transactivates HER2-neu in breast cancer cells by a novel pathway involving Src kinase activation

1 reference

7 January 2021

Nuclear factor-kappaB in cancer development and progression

1 reference

7 January 2021

Signaling pathways responsible for cancer cell invasion as targets for cancer therapy

1 reference

7 January 2021

HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

1 reference

7 January 2021

NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4

1 reference

7 January 2021

Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation

1 reference

7 January 2021

Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypox

1 reference

7 January 2021

The immunobiology of cancer immunosurveillance and immunoediting

1 reference

7 January 2021

Regulation of the trafficking of tumour-infiltrating dendritic cells by chemokines

1 reference

7 January 2021

Immunosuppressive networks in the tumour environment and their therapeutic relevance

1 reference

7 January 2021

The detection and localization of monocyte chemoattractant protein-1 (MCP-1) in human ovarian cancer

1 reference

7 January 2021

Tumour-educated macrophages promote tumour progression and metastasis

1 reference

7 January 2021

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

1 reference

7 January 2021

Regulatory T-cell compartmentalization and trafficking

1 reference

7 January 2021

CCR4 as a novel molecular target for immunotherapy of cancer

1 reference

7 January 2021

Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: the fragmin advanced malignancy outcome study (FAMOUS).

1 reference

7 January 2021

The monomer-dimer equilibrium of stromal cell-derived factor-1 (CXCL 12) is altered by pH, phosphate, sulfate, and heparin

1 reference

7 January 2021

New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and -independent effects

1 reference

7 January 2021

Oral bisphosphonates as adjuvant therapy for operable breast cancer

1 reference

7 January 2021

The bisphosphonate YM529 inhibits osteolytic and osteoblastic changes and CXCR-4-induced invasion in prostate cancer.

1 reference

7 January 2021

Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4.

1 reference

7 January 2021

Retention of CXCR4 in the endoplasmic reticulum blocks dissemination of a T cell hybridoma

1 reference

7 January 2021

CXCR4 knockdown by small interfering RNA abrogates breast tumor growth in vivo

1 reference

7 January 2021

CXCR4 regulates growth of both primary and metastatic breast cancer

1 reference

7 January 2021

CXCR4 and CXCL12 (SDF-1) in prostate cancer: inhibitory effects of human single chain Fv antibodies

1 reference

7 January 2021

Blockade of the Stromal Cell–Derived Factor-1/CXCR4 Axis AttenuatesIn vivoTumor Growth by Inhibiting Angiogenesis in a Vascular Endothelial Growth Factor–Independent Manner

1 reference

7 January 2021

The bicyclam AMD3100 story

1 reference

7 January 2021

Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist

1 reference

7 January 2021

T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer

1 reference

7 January 2021

A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists

1 reference

7 January 2021

Macrophage inflammatory protein 3alpha transgene attracts dendritic cells to established murine tumors and suppresses tumor growth

1 reference

7 January 2021

Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity

1 reference

7 January 2021

Lymphotactin expression by engineered myeloma cells drives tumor regression: mediation by CD4 and CD8 T cells and neutrophils expressing XCR1 receptor

1 reference

7 January 2021

Adenoviral vectors expressing lymphotactin and interleukin 2 or lymphotactin and interleukin 12 synergize to facilitate tumor regression in murine breast cancer models

1 reference

7 January 2021

Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

1 reference

7 January 2021

Combined chemokine and cytokine gene transfer enhances antitumor immunity

1 reference

7 January 2021

Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2

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7 January 2021

Chemokine receptor-mediated delivery directs self-tumor antigen efficiently into the class II processing pathway in vitro and induces protective immunity in vivo

1 reference

7 January 2021

Chemokine receptor targeting efficiently directs antigens to MHC class I pathways and elicits antigen-specific CD8 T-cell responses

1 reference

7 January 2021

Induction of tumor-specific protective immunity by in situ Langerhans cell vaccine

1 reference

7 January 2021

Genetic idiotypic and tumor cell-based vaccine strategies for indolent non Hodgkin's lymphoma

1 reference

7 January 2021

DNA vaccines encoding human immunodeficiency virus-1 glycoprotein 120 fusions with proinflammatory chemoattractants induce systemic and mucosal immune responses

1 reference

7 January 2021

Genetic fusions with viral chemokines target delivery of nonimmunogenic antigen to trigger antitumor immunity independent of chemotaxis

1 reference

7 January 2021

Identifiers

DOI

10.1002/CNCR.22706

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16 August 2017

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