Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding (Q36818139)

16 August 2017

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title

Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding (English)

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16 August 2017

author name string

Diomedes E Logothetis

series ordinal

1

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16 August 2017

Dmitry Lupyan

series ordinal

2

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16 August 2017

Avia Rosenhouse-Dantsker

series ordinal

3

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16 August 2017

language of work or name

English

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publication date

10 May 2007

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16 August 2017

published in

Journal of Physiology

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16 August 2017

volume

582

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16 August 2017

issue

Pt 3

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16 August 2017

page(s)

953-965

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PIP2 and PIP as determinants for ATP inhibition of KATP channels

16 August 2017

cites work

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Mutations in the ROMK gene in antenatal Bartter syndrome are associated with impaired K channel function

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PIP2 binding residues of Kir2.1 are common targets of mutations causing Andersen syndrome

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Characteristic interactions with phosphatidylinositol 4,5-bisphosphate determine regulation of kir channels by diverse modulators

21 January 2018

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Heterologous multimeric assembly is essential for K channel activity of neuronal and cardiac G-protein-activated inward rectifiers.

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Kir2.1 inward rectifier K channels are regulated independently by protein kinases and ATP hydrolysis

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Anionic phospholipids activate ATP-sensitive potassium channels

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Identification of critical residues controlling G protein-gated inwardly rectifying K( ) channel activity through interactions with the beta gamma subunits of G proteins

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Identification of a potassium channel site that interacts with G protein betagamma subunits to mediate agonist-induced signaling

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Molecular diversity and regulation of renal potassium channels

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Regulation of cardiac Na ,Ca2 exchange and KATP potassium channels by PIP2.

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Molecular mechanism for sodium-dependent activation of G protein-gated K channels

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Molecular determinants for sodium-dependent activation of G protein-gated K channels

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Cloning and expression of an inwardly rectifying ATP-regulated potassium channel

21 January 2018

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Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gβγ

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Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K channels

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Evidence that direct binding of Gβγ to the GIRK1 G protein-gated inwardly rectifying K channel is important for channel activation

5 September 2018

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Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K channel

21 January 2018

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Mechanism of PLC-mediated Kir3 current inhibition

21 January 2018

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G-protein beta gamma-subunits activate the cardiac muscarinic K -channel via phospholipase A2

21 January 2018

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The G-protein-gated atrial K channel IKACh is a heteromultimer of two inwardly rectifying K( )-channel proteins

21 January 2018

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Primary structure and functional expression of a mouse inward rectifier potassium channel

21 January 2018

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Identification of domains conferring G protein regulation on inward rectifier potassium channels

21 January 2018

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Crystal structure of the potassium channel KirBac1.1 in the closed state

21 January 2018

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Arachidonic acid metabolites as intracellular modulators of the G protein-gated cardiac K channel

21 January 2018

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Phosphatidylinositol 4,5-bisphosphate and intracellular pH regulate the ROMK1 potassium channel via separate but interrelated mechanisms

21 January 2018

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Regulation of ROMK1 channel by protein kinase A via a phosphatidylinositol 4,5-bisphosphate-dependent mechanism

21 January 2018

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Phosphoinositide-mediated gating of inwardly rectifying K( ) channels

21 January 2018

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Gating of G protein-sensitive inwardly rectifying K channels through phosphatidylinositol 4,5-bisphosphate

21 January 2018

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The beta gamma subunits of GTP-binding proteins activate the muscarinic K channel in heart.

21 January 2018

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Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification

21 January 2018

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Alterations in conserved Kir channel-PIP2 interactions underlie channelopathies

21 January 2018

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Molecular basis for the inhibition of G protein-coupled inward rectifier K( ) channels by protein kinase C

21 January 2018

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G-protein mediated gating of inward-rectifier K channels

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Ohmic conductance through the inwardly rectifying K channel and blocking by internal Mg2 .

21 January 2018

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Heterologous facilitation of G protein-activated K( ) channels by beta-adrenergic stimulation via cAMP-dependent protein kinase

21 January 2018

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Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution

21 January 2018

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Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification

21 January 2018

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Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1

21 January 2018

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21 January 2018

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GTP-binding proteins couple cardiac muscarinic receptors to a K channel.

21 January 2018

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Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome

21 January 2018

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Gating of inward rectifier K channels by proton-mediated interactions of N- and C-terminal domains

21 January 2018

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Inwardly rectifying potassium channels.

21 January 2018

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Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits

21 January 2018

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TrkB activation by brain-derived neurotrophic factor inhibits the G protein-gated inward rectifier Kir3 by tyrosine phosphorylation of the channel

21 January 2018

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Eicosanoids inhibit the G-protein-gated inwardly rectifying potassium channel (Kir3) at the Na /PIP2 gating site

21 January 2018

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Specificity of activation by phosphoinositides determines lipid regulation of Kir channels

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Assaying phosphatidylinositol bisphosphate regulation of potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Molecular characteristics of phosphoinositide binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Intracellular regulation of inward rectifier K channels

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Functional consequences of ROMK mutants linked to antenatal Bartter's syndrome and implications for treatment

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Structural determinants of PIP(2) regulation of inward rectifier K(ATP) channels

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Membrane phospholipid control of nucleotide sensitivity of KATP channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

ATP modulation of ATP-sensitive potassium channel ATP sensitivity varies with the type of SUR subunit

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Regulation of ion channels by phosphatidylinositol 4,5-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Na activation of the muscarinic K channel by a G-protein-independent mechanism

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Activation of the atrial K ACh channel by the βγ subunits of G proteins or intracellular Na ions depends on the presence of phosphatidylinositol phosphates

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Regulation of cardiac inwardly rectifying potassium channels by membrane lipid metabolism

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Inward rectification of a potassium channel in cardiac ventricular cells depends on internal magnesium ions

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Biophysical and molecular mechanisms underlying the modulation of heteromeric Kir4.1-Kir5.1 channels by CO2 and pH.

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Protein kinase C inhibits ROMK1 channel activity via a phosphatidylinositol 4,5-bisphosphate-dependent mechanism

21 January 2018

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https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Structural diversity in the cytoplasmic region of G protein-gated inward rectifier K channels.

21 January 2018

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Protein kinase A modulates PLC-dependent regulation and PIP2-sensitivity of K channels

5 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075264

Activation of inwardly rectifying potassium (Kir) channels by phosphatidylinosital-4,5-bisphosphate (PIP2): interaction with other regulatory ligands

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075264

Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel

5 September 2018

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Constitutively active and G-protein coupled inward rectifier K channels: Kir2.0 and Kir3.0.

5 September 2018

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The complex and intriguing lives of PIP2 with ion channels and transporters

5 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075264

Activation of inwardly rectifying K channels by distinct PtdIns(4,5)P2 interactions

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075264

Channelopathies of inwardly rectifying potassium channels

5 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075264

G protein gated potassium channels

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075264

G protein regulation of potassium ion channels

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075264

Renal potassium transport: mechanisms and regulation

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075264

Acetylcholine activation of K channels in cell-free membrane of atrial cells

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075264

A Switch Mechanism for Gβγ Activation of IKACh

5 September 2018

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2007.133157

Genetic heterogeneity of Bartter's syndrome revealed by mutations in the K channel, ROMK

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17495041

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[Mechanism of membrane effect of acetylcholine on myocardial fibers]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17495041

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1113/JPHYSIOL.2007.133157

1 reference

16 August 2017

0 references

1 reference